About james-kirkland, Ph.D. James L. Kirkland, M.D., Ph.D., is Director of the Robert and Arlene Kogod Center on Aging at
Mayo Clinic and Noaber Foundation Professor of Aging Research. Dr. Kirkland’s research is on
cellular senescence, age-related adipose tissue and metabolic dysfunction, and development of
agents and strategies for targeting fundamental aging mechanisms to treat age-related chronic
diseases and disabilities. He published the first article about agents that clear senescent cells –
senolytic drugs. He is a scientific advisory board member for multiple companies, academic
organizations, and governments. He is President-Elect of the American Federation for Aging
Research, a past member of the National Advisory Council on Aging of the National Institutes
of Health, and past chair of the Biological Sciences Section of the Gerontological Society of
America. He holds honorary appointments at Boston University and the University of
Groningen in the Netherlands. He is a board-certified specialist in internal medicine, geriatrics,
and endocrinology and metabolism.
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October 28, 2021
A team of researchers, including Dr. James Kirkland of Mayo Clinic, has published a review of the ongoing efforts of researchers to clear senescent cells through senolytics. Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are part;...
