Category: News
Hard Science and Long-Shot Ideas Meet in Vitalia
March 12, 2024
Vitalia, the longevity pop-up city that came into being earlier this year on the island of Roatan off the coast of Honduras, was a first-of-its-kind event that we will more
Reprogramming Cells to Research Aging
March 11, 2024
Instead of using cellular reprogramming to directly treat age-related diseases, a perspective published in Nature Communications focuses on the opposite: using reprogrammed cells to form aged tissues and organoids on
High Protein Consumption May Drive Atherosclerosis
March 8, 2024
A new study suggests that increased protein intake, specifically of the amino acid leucine, can exacerbate atherosclerosis by inhibiting autophagy in macrophages [1]. Protein: friend or foe? The protein we
Lowering the Bar to Invest in Longevity
March 7, 2024
Maximon, Marcuard Heritage, and GenTwo have announced the launch of a new longevity-related investment opportunity. Their proposal allows professional investors to get access to Maximon’s portfolio of longevity companies via
Looking for Safety in Epigenetic Rejuvenation
March 7, 2024
In Nature Communications, Ali Yücel and Vadim Gladyshev have published a review of the current state of the art in partial cellular reprogramming, detailing what this technology does and how
Intermittent Rapamycin Lessens Negative Effects in Mice
March 6, 2024
A recent Molecular Metabolism paper dives into the differences between intermittent and chronic rapamycin treatment and its differential impact on male and female mice [1]. The dark side of rapamycin
Decreasing Autophagy Might Reverse Ovarian Aging
March 5, 2024
Experimenting in vitro and in mice, scientists have found that ovarian aging is linked to increased autophagy and apoptosis in granulosa cells and that it can be reversed by an
Using Ultrasound to Assist Gene Therapy
March 4, 2024
A new publication in iScience has described a novel way in which heart tissue can be encouraged to accept a gene therapy by using ultrasound to create cavitation bubbles. A
Longevity and DeSci Recap – February 2024
March 4, 2024
Last month has been a hive of activity in the longevity finance sphere, with a number of significant fundings taking place that are set to generate new lifespan solutions for
Ultra-Processed Food Linked to Numerous Health Risks
March 1, 2024
A new massive umbrella review of epidemiological meta-analyses reinforces the idea that ultra-processed food is bad for most aspects of human health [1]. Is it even food? Many words have
Rejuvenation Roundup February 2024
March 1, 2024
The leap year is here, so we’ve had an extra day to showcase interviews and report on all-new ways to combat cancer. Here’s everything that we’ve published in February. LEAF
Niacin (Vitamin B3) Linked to Cardiovascular Risk
February 29, 2024
A new study shows that niacin, a popular food fortifier, supplement, and NAD precursor, might increase the risk of major adverse cardiovascular events by as much as twofold [1]. The
Higher Abdominal Fat Associated with Cognitive Decline
February 28, 2024
A group of Japanese researchers has published a paper reporting an association between higher abdominal fat levels and cognitive decline [1]. Abdominal fat and brain connection Aging is often linked
Physically Fit Older People Have Better Visual Processing
February 27, 2024
Publishing a study in GeroScience featuring people over 80 years old, researchers have described a link between physical fitness and maintenance of specific brain functions. Executive functions This paper begins
Epigenetic Clocks Help Predict Health Outcomes
February 26, 2024
Researchers publishing in PNAS have found that well-known epigenetic clocks are valuable in predicting health outcomes, including mortality, in human beings. The usefulness of clocks This paper begins with a
Hard Science and Long-Shot Ideas Meet in Vitalia
March 12, 2024
Vitalia, the longevity pop-up city that came into being earlier this year on the island of Roatan off the coast of Honduras, was a first-of-its-kind event that we will more extensively cover later. Today, we are happy to present a roundup of the talks from the
Reprogramming Cells to Research Aging
March 11, 2024
Instead of using cellular reprogramming to directly treat age-related diseases, a perspective published in Nature Communications focuses on the opposite: using reprogrammed cells to form aged tissues and organoids on which to conduct experiments. Why not just use donors? Obviously, there is no shortage of age-related
High Protein Consumption May Drive Atherosclerosis
March 8, 2024
A new study suggests that increased protein intake, specifically of the amino acid leucine, can exacerbate atherosclerosis by inhibiting autophagy in macrophages [1]. Protein: friend or foe? The protein we get from food is indispensable, as it allows us to produce our own proteins, but the
Lowering the Bar to Invest in Longevity
March 7, 2024
Maximon, Marcuard Heritage, and GenTwo have announced the launch of a new longevity-related investment opportunity. Their proposal allows professional investors to get access to Maximon’s portfolio of longevity companies via an actively managed certificate (AMC). According to Maximon, there have been many requests to launch an
Looking for Safety in Epigenetic Rejuvenation
March 7, 2024
In Nature Communications, Ali Yücel and Vadim Gladyshev have published a review of the current state of the art in partial cellular reprogramming, detailing what this technology does and how it might be used safely. Affecting methylation directly This paper begins by treading familiar ground on
Intermittent Rapamycin Lessens Negative Effects in Mice
March 6, 2024
A recent Molecular Metabolism paper dives into the differences between intermittent and chronic rapamycin treatment and its differential impact on male and female mice [1]. The dark side of rapamycin Rapamycin doesn’t need much introduction in the lifespan extension community. This mTOR inhibitor has been shown
Decreasing Autophagy Might Reverse Ovarian Aging
March 5, 2024
Experimenting in vitro and in mice, scientists have found that ovarian aging is linked to increased autophagy and apoptosis in granulosa cells and that it can be reversed by an estrogen receptor inhibitor [1]. When ovaries get tired Female reproductive aging is an intriguing phenomenon that
Using Ultrasound to Assist Gene Therapy
March 4, 2024
A new publication in iScience has described a novel way in which heart tissue can be encouraged to accept a gene therapy by using ultrasound to create cavitation bubbles. A little-known target and a new delivery vector This paper begins with a discussion of S-adenosylhomocysteine (SAH),
Longevity and DeSci Recap – February 2024
March 4, 2024
Last month has been a hive of activity in the longevity finance sphere, with a number of significant fundings taking place that are set to generate new lifespan solutions for the future. Highlights include Yuva Biosciences’ $7.5 million for anti-hair loss tech, Tagomics’ £6.7 million for
Ultra-Processed Food Linked to Numerous Health Risks
March 1, 2024
A new massive umbrella review of epidemiological meta-analyses reinforces the idea that ultra-processed food is bad for most aspects of human health [1]. Is it even food? Many words have been uttered about the dangers of ultra-processed food, so can another study add anything new? The
Rejuvenation Roundup February 2024
March 1, 2024
The leap year is here, so we’ve had an extra day to showcase interviews and report on all-new ways to combat cancer. Here’s everything that we’ve published in February. LEAF News Interviews Patrick Linden’s Case Against Death: People come to the longevity field from all walks
Niacin (Vitamin B3) Linked to Cardiovascular Risk
February 29, 2024
A new study shows that niacin, a popular food fortifier, supplement, and NAD precursor, might increase the risk of major adverse cardiovascular events by as much as twofold [1]. The dark side of niacin? Vitamins are good for you, but caveats apply. Too much of some
Higher Abdominal Fat Associated with Cognitive Decline
February 28, 2024
A group of Japanese researchers has published a paper reporting an association between higher abdominal fat levels and cognitive decline [1]. Abdominal fat and brain connection Aging is often linked to many comorbidities, one of which is dementia, and developing drugs to treat this condition is
Physically Fit Older People Have Better Visual Processing
February 27, 2024
Publishing a study in GeroScience featuring people over 80 years old, researchers have described a link between physical fitness and maintenance of specific brain functions. Executive functions This paper begins with a description of executive functions, the basic abilities involved in performing the fundamental goal-oriented behaviors
Epigenetic Clocks Help Predict Health Outcomes
February 26, 2024
Researchers publishing in PNAS have found that well-known epigenetic clocks are valuable in predicting health outcomes, including mortality, in human beings. The usefulness of clocks This paper begins with a discussion of epigenetic clocks, most notably the later-generation clocks, such as PhenoAge, DunedinPACE, and the strong