Category: Biology of Aging
Scientists Modify Lettuce to Make Orally Available Insulin
June 23, 2023
Researchers have genetically engineered lettuce to produce human insulin. The resulting plant-based drug, which can be taken orally, was successfully tested in mice [1]. An epidemic and a costly
Dr. Matthew Walker Tells Us Why We Sleep
June 20, 2023
“Why We Sleep: Unlocking the Power of Sleep and Dreams” by Matthew Walker, renowned sleep research scientist and psychiatry professor at Harvard, is a comprehensive exploration of sleep that offers
Bacteria May Be Fueling Cancer with Methionine
June 20, 2023
Scientists have found that the tumor microenvironment in lung adenocarcinoma favors methionine-producing bacteria, which, in turn, help the cancer survive nutrient scarcity [1]. Micro-friends or micro-foes? Our bodies host a
Clinical Trial: Collagen Peptides Reduce AGEs in Skin
June 19, 2023
A placebo-controlled, double-blinded human clinical trial published in Bioscience, Biotechnology, and Biochemistry has determined that collagen peptide ingestion reduces the amount of advanced glycation end-products (AGEs) in the skin. When
Shingles Vaccine May Protect Against Alzheimer’s
June 16, 2023
New research suggests that vaccination against shingles, a disease caused by the varicella zoster virus, can provide some protection against Alzheimer’s disease, mostly in women [1]. Viruses and aging With
How Cancer Hijacks the Nervous System
June 15, 2023
A review article published in Nature has outlined the current research into how the nervous system’s signals affect cancer growth. A surprising connection This review opens with a bold but
Rapamycin Users Report Positive Effects in Survey
June 14, 2023
A new study published in GeroScience addresses the efficacy and side effects of off-label rapamycin as a preventive therapy to maintain healthspan [1]. From a small island to a reportedly
Sirtuins May Help Against Inflammatory Spinal Degeneration
June 12, 2023
Researchers publishing in Aging have outlined a relationship between disc degeneration, macrophage polarization, inflammation, and sirtuins, demonstrating their effectiveness in a rat model of the disease. A crippling and painful
How Superior DNA Repair Gives Bowhead Whales Longevity
June 9, 2023
Scientists have found a possible explanation for bowhead whales’ exceptional lifespan, and it might be translatable to humans [1]. More cells, less cancer With some exceptions, body size is strongly
How Donated Stem Cells Become Functional Cells
June 8, 2023
Scientists have verified the effectiveness of stem cell transplants, researched a core reason behind it, and published their findings in Aging Cell. The niche controls what stem cells do Back
Castration Influences Growth and Median Lifespan in Mice
June 7, 2023
Research published in Aging Cell has discovered that castrated male mice show similarities to females in growth and lifespan [1]. It is widely known that women outlive men on average,
Michael Lustgarten Fights Back Against Microbes
June 6, 2023
Dr. Michael Lustgarten delivers a clear and enlightening exploration of the intricate relationship between microbial burden and aging in Microbial Burden: A Major Cause of Aging and Age-Related Disease and
Giving Old Stem Cells Lasting Youthful Powers
June 5, 2023
Researchers publishing in Cell Proliferation have described factors that appear to give old muscle stem cells the ability to effectively proliferate and differentiate for a very long time. When renewal
Benefits of Dasatinib and Quercetin Treatment in Monkeys
June 2, 2023
In one of the first studies of its kind, the popular senolytic combination, administered systematically for six months, produced several health benefits in these animals. Some effects were augmented by
Linking Bile Duct Blockage and Cellular Senescence
June 1, 2023
Research published in Aging has shed new light on the relationship between certain liver diseases and cellular senescence. Clogged bile ducts and senescence There are multiple documented causes of cellular
Scientists Modify Lettuce to Make Orally Available Insulin
June 23, 2023
Researchers have genetically engineered lettuce to produce human insulin. The resulting plant-based drug, which can be taken orally, was successfully tested in mice [1]. An epidemic and a costly drug Diabetes mellitus has reached epidemic proportions, affecting about half a billion people worldwide. This debilitating
Dr. Matthew Walker Tells Us Why We Sleep
June 20, 2023
“Why We Sleep: Unlocking the Power of Sleep and Dreams” by Matthew Walker, renowned sleep research scientist and psychiatry professor at Harvard, is a comprehensive exploration of sleep that offers a rich blend of science, research, and practical advice. The book is divided into four parts,
Bacteria May Be Fueling Cancer with Methionine
June 20, 2023
Scientists have found that the tumor microenvironment in lung adenocarcinoma favors methionine-producing bacteria, which, in turn, help the cancer survive nutrient scarcity [1]. Micro-friends or micro-foes? Our bodies host a mind-bending number of microorganisms, but most effects of this cohabitation are not well understood. Scientists have
Clinical Trial: Collagen Peptides Reduce AGEs in Skin
June 19, 2023
A placebo-controlled, double-blinded human clinical trial published in Bioscience, Biotechnology, and Biochemistry has determined that collagen peptide ingestion reduces the amount of advanced glycation end-products (AGEs) in the skin. When the Maillard reaction is a problem AGEs have been known to be harmful for decades [1],
Shingles Vaccine May Protect Against Alzheimer’s
June 16, 2023
New research suggests that vaccination against shingles, a disease caused by the varicella zoster virus, can provide some protection against Alzheimer’s disease, mostly in women [1]. Viruses and aging With causes of many age-related diseases remaining unclear, in recent years, scientists have been looking into the
How Cancer Hijacks the Nervous System
June 15, 2023
A review article published in Nature has outlined the current research into how the nervous system’s signals affect cancer growth. A surprising connection This review opens with a bold but heavily documented claim: the central nervous system (CNS) affects various cancers through signaling mechanisms, even those
Rapamycin Users Report Positive Effects in Survey
June 14, 2023
A new study published in GeroScience addresses the efficacy and side effects of off-label rapamycin as a preventive therapy to maintain healthspan [1]. From a small island to a reportedly life-extending drug When it was discovered in 1972 on the island of Rapa Nui, rapamycin was
Sirtuins May Help Against Inflammatory Spinal Degeneration
June 12, 2023
Researchers publishing in Aging have outlined a relationship between disc degeneration, macrophage polarization, inflammation, and sirtuins, demonstrating their effectiveness in a rat model of the disease. A crippling and painful disease Intervertebral disc degeneration (IDD) is a major cause of pain and disability [1], as it
How Superior DNA Repair Gives Bowhead Whales Longevity
June 9, 2023
Scientists have found a possible explanation for bowhead whales’ exceptional lifespan, and it might be translatable to humans [1]. More cells, less cancer With some exceptions, body size is strongly correlated with longevity across species. While this can be explained evolutionarily (larger species have fewer extrinsic
How Donated Stem Cells Become Functional Cells
June 8, 2023
Scientists have verified the effectiveness of stem cell transplants, researched a core reason behind it, and published their findings in Aging Cell. The niche controls what stem cells do Back in 1978, Raymond Schofield proposed that hematopoietic stem cells (HSCs), which make blood cells, are governed
Castration Influences Growth and Median Lifespan in Mice
June 7, 2023
Research published in Aging Cell has discovered that castrated male mice show similarities to females in growth and lifespan [1]. It is widely known that women outlive men on average, but the biological reasons are still not fully understood. As it is challenging to experimentally test
Michael Lustgarten Fights Back Against Microbes
June 6, 2023
Dr. Michael Lustgarten delivers a clear and enlightening exploration of the intricate relationship between microbial burden and aging in Microbial Burden: A Major Cause of Aging and Age-Related Disease and What We Can Do to Fight Back! Through meticulous research and compelling analysis, the author sheds
Giving Old Stem Cells Lasting Youthful Powers
June 5, 2023
Researchers publishing in Cell Proliferation have described factors that appear to give old muscle stem cells the ability to effectively proliferate and differentiate for a very long time. When renewal runs out Many of the problems that elderly people face in daily life, such as frailty,
Benefits of Dasatinib and Quercetin Treatment in Monkeys
June 2, 2023
In one of the first studies of its kind, the popular senolytic combination, administered systematically for six months, produced several health benefits in these animals. Some effects were augmented by caloric restriction [1]. Coup de grâce for cells The combination of the drug dasatinib and the
Linking Bile Duct Blockage and Cellular Senescence
June 1, 2023
Research published in Aging has shed new light on the relationship between certain liver diseases and cellular senescence. Clogged bile ducts and senescence There are multiple documented causes of cellular senescence, such as radiation and chemical insults, which are frequently performed in experiments to test senescence