Category: Research

Longeveron

Longeveron Takes Aim at Aging with Cell Therapy

Longeveron has just announced the first data from its Phase 2b clinical trial that targets frailty with Lomecel-B, an MSC-based cell therapy. A longevity strategy built in More and more,

DNA Blood Cells

Stem Cell Helper Heat Shock Protein Identified

Researchers publishing in Cell Stem Cell have identified a protein that helps hematopoietic stem cells (HSCs) both in ex vivo cultures and in aging tissues. The problem with culturing cells

Storm

Senescent Cells and the Cytokine Storm

Research recently published in Aging shows how senescent cells overreact to inflammatory stimuli, causing them to excessively excrete compounds that promote inflammation. The researchers hypothesize that this is one cause

Clock

A New Clock Tracks Inflammatory Aging

Epigenetic clocks have become a mainstay of longevity research over the past few years, with new clocks regularly being established for different species and tissues as well as promising research

Sleeping Mouse

The Links Between Sleep Deprivation and Aging

Publishing in the journal Aging, a team of Russian researchers has shown what happens to the cognitive capabilities and brain structures of young and old sleep-deprived mice. Sleep-deprived mice act

Oocyte

Gene Found to Restore Egg Cell Function in Mice

A study conducted at the Institute of Reproductive Medicine in South Korea has shown that the protein expressed by growth-associated gene 6 (GAS6) ameliorates age-related decline in egg cells (oocytes).

Stressful stimuli

Stress, Sensory Gating, and Cognitive Decline With Age

Researchers publishing in Aging have found that stresses, both biological and in daily life, harm one of our fundamental abilities to correctly process what’s going on around us. What is sensory gating? Sensory gating is the brain’s ability to filter out irrelevant stimuli after the first

Longeveron

Longeveron Takes Aim at Aging with Cell Therapy

Longeveron has just announced the first data from its Phase 2b clinical trial that targets frailty with Lomecel-B, an MSC-based cell therapy. A longevity strategy built in More and more, biotech start-ups are applying longevity strategies to their therapeutic pipelines. Among them, Longeveron stands out as

Mouse Brain Internal

The Hedgehog Protein Reduces Microglial Inflammation in Mice

Researchers, publishing in the journal Aging, have discovered that a protein called hedgehog alleviates the tissue-specific, age-related inflammation of the microglia, the maintenance cells of the brain. The aging differences between tissue types To begin this research, the team first performed a gene expression analysis on

DNA Blood Cells

Stem Cell Helper Heat Shock Protein Identified

Researchers publishing in Cell Stem Cell have identified a protein that helps hematopoietic stem cells (HSCs) both in ex vivo cultures and in aging tissues. The problem with culturing cells As the researchers explain, HSCs give rise to both red and white blood cells, making their

Storm

Senescent Cells and the Cytokine Storm

Research recently published in Aging shows how senescent cells overreact to inflammatory stimuli, causing them to excessively excrete compounds that promote inflammation. The researchers hypothesize that this is one cause of the cytokine storm, an immune overreaction that is more common in the elderly and is

Clock

A New Clock Tracks Inflammatory Aging

Epigenetic clocks have become a mainstay of longevity research over the past few years, with new clocks regularly being established for different species and tissues as well as promising research that uses and builds on these clocks. An international research team has recently created a different

Old and young collagen

Young ECM Expression in Predicting Longevity Drug Discovery

A recent study published in Aging Cell has turned up potential new therapeutics to target the aging extracellular matrix (ECM). Longevity drug discovery  The discovery of new targets injects fresh lifeblood into the race to develop anti-aging compounds. The strategies used to identify these targets have

Stroke Recovery

Computer Modeling Rapamycin Derivatives for Treating Stroke

In a study published in Aging, Chinese researchers have described how they used computer modeling in order to create a new rapalog that is designed to reduce the long-term impact of stroke. Reperfusion injury, autophagy, and mTORC1 Stroke and other ischemic events, such as heart attack,

Exercising with data

Humanity Launches an App to Help You Slow Down Aging

Humanity has launched a longevity app in the UK that could help you stay healthier for longer and potentially achieve longevity. The HUMANITY app has been launched on the iPhone, and it is due to get an Android version in the near future. This longevity app

Gut Brain Connection

The Aging Microbiome Impacts Immune Function in the Brain

Aging causes changes to the diversity and numbers of bacteria that live in our guts, and it has become a growing area of interest for researchers in recent years. The gut microbiome The gut microbiome is a constantly changing environment populated by vast numbers and types

Old Fact Check

The Facts and Fiction of the Movie Old

I started to like sci-fi movies as a child, and I am still a fan. However the more I learn about science and technology, the harder it is to ignore inconsistencies and fantasy the producers present as facts in order to excite the viewer. One can

Older people playing chess

Cognition Has Improved in Older Adults Between 2004 and 2013

New research in humans published in PLoS ONE shows society-wide improvements in cognition for older adults, but it also highlights a need to specifically target age-related cognitive decline. Humans have gotten much smarter over time Cognition is a broad term used to refer to many different

Sleeping Mouse

The Links Between Sleep Deprivation and Aging

Publishing in the journal Aging, a team of Russian researchers has shown what happens to the cognitive capabilities and brain structures of young and old sleep-deprived mice. Sleep-deprived mice act somewhat like sleep-deprived people This experiment used three groups of mice, each of which had two

Oocyte

Gene Found to Restore Egg Cell Function in Mice

A study conducted at the Institute of Reproductive Medicine in South Korea has shown that the protein expressed by growth-associated gene 6 (GAS6) ameliorates age-related decline in egg cells (oocytes). A protein with many functions Like many other proteins, the GAS6 protein serves multiple functions. It

UCSD Blood Flow Monitor

New Patch Uses Ultrasound Array to Monitor Blood Flow

Researchers from the University of California San Diego have developed a new non-invasive way to measure blood flow using an ultrasound patch [1]. Realtime blood flow monitoring just got easier This new flexible polymer patch sticks to the skin and can monitor the flow of blood