Lifespan Research Institute

Category: News

Editorial

Springtime for the Longevity Industry

If you are in the Northern Hemisphere, then spring is well underway and the weather is warming up. This is the season of renewal and growth. With that in mind,

Neurons

New Insights Into How Neural Stem Cells Age

Researchers publishing in Aging Cell have used single-cell transcriptomics to discover new insights into how neural stem cells (NSCs) change with aging. Adults do generate neurons The adult brain does

Rejuvenation Roundup May 2025

Rejuvenation Roundup May 2025

May was a substantial month in the rejuvenation biotechnology world, including nanomedical advancements, T cells to fight senescence, a transcription factor with multiple potential uses, and the Hallmarks of Aging

Blood plasma tubes

How Plasma Exchange Affects Aging in a Human Trial

A placebo-controlled clinical trial, with results published in Aging Cell, has determined that plasma replacement has beneficial effects when combined with immunoglobulin, according to multiple epigenetic clocks and -omics biomarkers.

Bowhead whales

Why Some Mammals Live Much Longer Than Others

A recent study investigated differences in maximum lifespan potential among different mammalian species. The researchers found associations between gene family size expansion, maximum lifespan potential, and relative brain size. They

Sunlight

Vitamin D Rescues Telomere Attrition in Leukocytes

A sub-study, which was part of the large-scale VITAL trial, determined that vitamin D supplementation slows telomere attrition in leukocytes almost to a halt. This could have real-life clinical implications

Boyang Wang Interview

Boyang Wang on Targeting Underfunded Longevity Projects

In this interview, Boyang Wang of Immortal Dragons discusses the kinds of projects he wants to fund, ways in which the industry can be encouraged to develop, relationships between the East and West in longevity research and development, and what got him involved in longevity. Hello,

Assisting elderly

Younger Cohorts Show Less Dementia at the Same Age

While the overall prevalence of dementia might be rising due to population aging, a study has found that today’s older people seem to be less prone to dementia than in the past [1]. Are we having more dementia or less? While the robust rise in average

Editorial

Springtime for the Longevity Industry

If you are in the Northern Hemisphere, then spring is well underway and the weather is warming up. This is the season of renewal and growth. With that in mind, let’s take a look at what the Lifespan and LRI team has been up to. Top

Neurons

New Insights Into How Neural Stem Cells Age

Researchers publishing in Aging Cell have used single-cell transcriptomics to discover new insights into how neural stem cells (NSCs) change with aging. Adults do generate neurons The adult brain does generate new neurons [1], particularly in the hippocampus, the part of the brain responsible for memory

Rejuve.ai Interview

Rejuve.AI: Just Another App or a Longevity Research Network?

On its website, Rejuve.AI, a company co-founded by its dynamic CEO, Jasmine Smith, and a renowned AI researcher, Ben Goertzel, promises a lot of things: to “democratize longevity, globally,” to enable you to “take control of your data, and harness its earning potential,” and to “unite

Staying up late

Educated ‘Night Owls’ Might Have More Cognitive Decline Risk

A recent analysis of over 20,000 middle-aged and older adults showed an association between a later chronotype (‘night owls’) and cognitive decline among highly educated people [1]. Early birds and night owls One risk factor linked to dementia is a disrupted circadian rhythm, the natural 24-hour

Disappearing brain

Blunting an Inflammatory Pathway Slows Alzheimer’s in Mice

Scientists have demonstrated that knocking out part of the cGAS-STING DNA-sensing pathway slows disease progression in a mouse model of Alzheimer’s, calming down microglia and protecting neurons [1]. STING operation Inflammation is central to the pathogenesis of Alzheimer’s disease [2], which is accompanied by the accumulation

Rejuvenation Roundup May 2025

Rejuvenation Roundup May 2025

May was a substantial month in the rejuvenation biotechnology world, including nanomedical advancements, T cells to fight senescence, a transcription factor with multiple potential uses, and the Hallmarks of Aging lab discussing two more hallmarks. LEAF News Longevity Investor Network 2024 End of Year Update: Developing

Curious lab mouse

A Drug Combo Increases Lifespan in Mice by Over 30%

Combining rapamycin with the anti-cancer drug trametinib produced a synergistic effect and robust life extension in a new study [1]. A multi-node approach Rapamycin, which was first widely used as an immunosuppressant for transplant patients and is also used in oncology, is considered one of the

Blood plasma tubes

How Plasma Exchange Affects Aging in a Human Trial

A placebo-controlled clinical trial, with results published in Aging Cell, has determined that plasma replacement has beneficial effects when combined with immunoglobulin, according to multiple epigenetic clocks and -omics biomarkers. Looking for a signal Therapeutic plasma exchange (TPE), the practice of extracting and replacing a person’s

Bowhead whales

Why Some Mammals Live Much Longer Than Others

A recent study investigated differences in maximum lifespan potential among different mammalian species. The researchers found associations between gene family size expansion, maximum lifespan potential, and relative brain size. They also studied genomic features linked to lifespan evolution [1]. Maximum lifespan potential Maximum lifespan potential can

Bone marrow production

DNA Methylation Patterns Trace Blood Aging Dynamics

Scientists have created a new, highly effective method of tracing blood cells’ lineage. This can improve our understanding of clonal hematopoiesis and its impact on an aging organism [1]. Hostile takeover In the human body, a relatively small pool of hematopoietic stem cells (HSCs) sustains a

Rhesus macaques

Caloric Restriction Slows Ovarian Aging in Monkeys

In Aging, researchers have published their discovery that three years of caloric restriction in rhesus macaques that are beginning to enter menopause slows their ovarian aging. Closer to people than mice The ovary is one of the first human organs to be seriously affected by aging,

Sunlight

Vitamin D Rescues Telomere Attrition in Leukocytes

A sub-study, which was part of the large-scale VITAL trial, determined that vitamin D supplementation slows telomere attrition in leukocytes almost to a halt. This could have real-life clinical implications [1]. The chromosome guardians Attrition of telomeres, repetitive sequences that cap chromosomes, is one of the

Outdoor mouse

Common Laboratory Mice Age Faster in a Natural Environment

In Aging Cell, researchers have found that exposing ordinary Black 6 mice to a more natural environment accelerates rather than slows the aging of their livers. When natural doesn’t mean better It is a well-known fact that laboratory animals live in controlled conditions beyond that of