Category: News
Review of Juvenescence: Investing in the Age of Longevity
September 27, 2017
Only two years ago, when I launched my advocacy website Rejuvenaction, I didn’t think I would read a book like Juvenescence so soon; yet, the topic of rejuvenation biotechnologies has
Forget ‘live fast, die young’ – do the opposite instead
September 26, 2017
So far, the only intervention that is known to consistently increase lifespan across multiple species is caloric restriction (CR). Caloric restriction is known to increase lifespan in the majority of
Open Consultation of the WHO on Research Priorities for Healthy Aging
September 23, 2017
Very recently, the World Health Organization, which is essentially the United Nations’ agency for coordinating international health-related efforts, has launched The Global Online Consultation on Research Priority Setting for Healthy
Investing in the Age of Longevity
September 18, 2017
Today, we are pleased to announce the imminent arrival of Jim Mellon and Al Chalabi’s new book Juvenescence, which covers the field of rejuvenation biotechnology. The book focuses on technologies
Reviewing Stem Cell Therapies for Osteoporosis
September 4, 2017
Osteoporosis is a crippling condition provoked by an imbalance between the creation of new bone tissue and the destruction of the old, which becomes worse as we age. What causes
Fighting Aging and Hurricane Harvey: AgeMeter Campaign Extension and Matching Funds Announced
September 1, 2017
Aging remains the number one killer, taking the lives of 100,000 people per day due to a number of severe age-related diseases like cancer, heart disease, and Alzheimer’s. Still, this
MitoSENS Update August 2017
August 25, 2017
The following is an update from MitoSENS scientist Dr. Matthew “Oki” O’Connor: Hi, everyone! Long time, no update – my fault! As you all saw, our manuscript that was supported
False Positives in Senescent Cell Detection
August 19, 2017
Macrophages with markers of cellular senescence may not be senescent Researchers commonly determine the presence of senescent cells through the use of the p16ink4a (p16) and β-galactosidase biomarkers. Senescent cells
How Misfolded Proteins Cause Age-related Diseases
August 11, 2017
Coming from a fusion of the words ‘protein’ (a molecule that a cell uses as a machine or scaffolding) and ‘stasis’ (meaning to keep the same), the term ‘proteostasis’ can
Restoring Youthful Plasticity in the Brains of Old Mice
August 9, 2017
As we age, our brains lose their flexibility; this, in turn, affects our ability to learn, to remember things and to adapt to new situations. The classic example is of
Senolytics as a Potential Treatment for Lung Fibrosis
August 8, 2017
Today, we have a new study in which researchers focus on pulmonary fibrosis and the role of cellular senescence. What is pulmonary fibrosis? Pulmonary fibrosis causes scarring of lung tissue,
George Church – Turn Back Time to End Age-related Diseases
August 1, 2017
Many of you will likely already know who Professor George Church is, and that he is an important and senior member of the research community engaged in treating the aging
New Study Suggests Previous Concerns about CRISPR Safety are Questionable
July 26, 2017
Gene editing aims to make precise changes to the target DNA whilst avoiding altering other parts of the DNA. The objective of this is to remove undesirable genetic traits and
The real cost of life extension advocacy
July 20, 2017
There is a persistent view that life extension advocacy is something that does not require any investment and can be done in your spare time. Fundraising for overhead expenses is
Reprogramming Cells to Seek and Destroy Brain Cancer
July 6, 2017
A new type of cell that can seek and destroy brain cancer and then dispose of themselves has just been successfully tested in mice. The cells are able to home
Review of Juvenescence: Investing in the Age of Longevity
September 27, 2017
Only two years ago, when I launched my advocacy website Rejuvenaction, I didn’t think I would read a book like Juvenescence so soon; yet, the topic of rejuvenation biotechnologies has already become mainstream enough to lead investors of the calibre of Jim Mellon and Al Chalabi
Forget ‘live fast, die young’ – do the opposite instead
September 26, 2017
So far, the only intervention that is known to consistently increase lifespan across multiple species is caloric restriction (CR). Caloric restriction is known to increase lifespan in the majority of mouse strains tested [1] and many other species. The effects of CR have even been shown
Open Consultation of the WHO on Research Priorities for Healthy Aging
September 23, 2017
Very recently, the World Health Organization, which is essentially the United Nations’ agency for coordinating international health-related efforts, has launched The Global Online Consultation on Research Priority Setting for Healthy Aging. A corresponding survey is available on the WHO website and can be filled until September
Investing in the Age of Longevity
September 18, 2017
Today, we are pleased to announce the imminent arrival of Jim Mellon and Al Chalabi’s new book Juvenescence, which covers the field of rejuvenation biotechnology. The book focuses on technologies that will soon arrive, therapies that may increase healthy lifespan, and guidance for investors. The book
Reviewing Stem Cell Therapies for Osteoporosis
September 4, 2017
Osteoporosis is a crippling condition provoked by an imbalance between the creation of new bone tissue and the destruction of the old, which becomes worse as we age. What causes osteoporosis to develop and progress? Osteoporosis is the failure of tissue maintenance in the bones, causing
Fighting Aging and Hurricane Harvey: AgeMeter Campaign Extension and Matching Funds Announced
September 1, 2017
Aging remains the number one killer, taking the lives of 100,000 people per day due to a number of severe age-related diseases like cancer, heart disease, and Alzheimer’s. Still, this is not the only danger we have to protect ourselves from: the recent developments in the
MitoSENS Update August 2017
August 25, 2017
The following is an update from MitoSENS scientist Dr. Matthew “Oki” O’Connor: Hi, everyone! Long time, no update – my fault! As you all saw, our manuscript that was supported by lifespan.io donors was published last fall. Dr. Boominathan and I have been presenting our results
False Positives in Senescent Cell Detection
August 19, 2017
Macrophages with markers of cellular senescence may not be senescent Researchers commonly determine the presence of senescent cells through the use of the p16ink4a (p16) and β-galactosidase biomarkers. Senescent cells are known to exhibit both of these biomarkers, but it seems that they are not the
How Misfolded Proteins Cause Age-related Diseases
August 11, 2017
Coming from a fusion of the words ‘protein’ (a molecule that a cell uses as a machine or scaffolding) and ‘stasis’ (meaning to keep the same), the term ‘proteostasis’ can essentially be simplified into “Each function reliant on proteins is running as it should. There are
Restoring Youthful Plasticity in the Brains of Old Mice
August 9, 2017
As we age, our brains lose their flexibility; this, in turn, affects our ability to learn, to remember things and to adapt to new situations. The classic example is of older people who are stuck in a rut and unable to change how they think. Some
Senolytics as a Potential Treatment for Lung Fibrosis
August 8, 2017
Today, we have a new study in which researchers focus on pulmonary fibrosis and the role of cellular senescence. What is pulmonary fibrosis? Pulmonary fibrosis causes scarring of lung tissue, which results in the progressive loss of lung function over time. When the disease’s origin is
George Church – Turn Back Time to End Age-related Diseases
August 1, 2017
Many of you will likely already know who Professor George Church is, and that he is an important and senior member of the research community engaged in treating the aging processes to prevent or reverse age-related diseases, not to mention all kinds of other applications for
New Study Suggests Previous Concerns about CRISPR Safety are Questionable
July 26, 2017
Gene editing aims to make precise changes to the target DNA whilst avoiding altering other parts of the DNA. The objective of this is to remove undesirable genetic traits and introduce desirable changes in both plants and animals. For example, it could be used to make
The real cost of life extension advocacy
July 20, 2017
There is a persistent view that life extension advocacy is something that does not require any investment and can be done in your spare time. Fundraising for overhead expenses is like the proverbial elephant in the room: it is hard not to notice it is there,
Reprogramming Cells to Seek and Destroy Brain Cancer
July 6, 2017
A new type of cell that can seek and destroy brain cancer and then dispose of themselves has just been successfully tested in mice. The cells are able to home in on brain tumors and reduce them to between 2 to 5% of their original size[1].