Category: News
Inflammation May Drive Fat Distribution in Older People
August 15, 2024
A new study published in Aging Cell has detailed what happens to individual fat cells in white adipose tissue (WAT) as they age. When fat is more than just fat
A Botanical Extract Extends Lifespan and Healthspan in Mice
August 14, 2024
According to a new study, a polyphenol-rich natural extract positively impacts lifespan, healthspan, and cellular senescence. These results were observed in both cell culture and a mouse model [1]. From
NMN Increases Lifespan in Female Mice
August 13, 2024
A new preprint from David Sinclair’s lab has discovered that NMN supplementation started in midlife increases median and maximal lifespan in female mice and boosts healthspan in males [1]. NAD
A Ketosis-Related Compound Alleviates Arthritis in Rats
August 12, 2024
In Aging Cell, researchers have published details on the pathway by which a compound commonly found in ketone bodies ameliorates osteoarthritis in a rat model. Chondrocytes are crucial in arthritis
Michael Antonov: from Oculus to Longevity Biotech
August 9, 2024
After Oculus was sold to Facebook for two billion dollars a decade ago, Michael Antonov, one of the founders, could have become a major tech investor, a popular podcaster with
Immune Peptide Might Keep White Blood Cells Contained
August 8, 2024
In npj Aging, researchers have described how immune cell infiltration in inflammaging can be reduced with an immune-related peptide in a mouse model. Immune cell infiltration In a previous paper,
Fecal Microbiota Transplants Reduce Vascular Aging in Mice
August 7, 2024
Fecal microbiota transplantation from young mice to older mice improved multiple metabolic parameters and some hallmarks of aging, such as inflammation and telomere shortening [1]. Bringing back the balance Dysbiosis,
Hyperbaric Oxygen Therapy Increases Fitness in Elderly
August 6, 2024
In a new study, a 12-week protocol of hyperbaric oxygen therapy (HBOT) resulted in marked increases in aerobic capacity and cardiac blood flow [1]. Building pressure HBOT involves placing patients
New Epigenetic Clock Built on Lurking DNA Fragments
August 5, 2024
In Aging Cell, a team of researchers has announced Retroelement-Age, a novel clock that focuses on the expression of buried pieces of DNA that are normally suppressed. Corrupted but unexpressed
Longevity and DeSci Recap – July 2024
August 5, 2024
The Longevity and DeSci Recap is back, and our latest edition covers high-profile events including the Longevity Investors Conference in Gstaad, new innovations in AFib monitoring, and even some celebrity-related
Vegan Diet Lowers Biological Age in a New Study
August 2, 2024
In a study that involved pairs of identical twins, Stanford scientists have shown that a healthy vegan diet leads to a decrease in biological age and possibly to other health
Rapamycin + Trametinib Increase Mouse Lifespan by up to 35%
August 1, 2024
Combining rapamycin and trametinib seemed to have a cumulative effect in both sexes but mostly in females [1]. These results are probably due to a reduction in both cancer and
Rejuvenation Roundup July 2024
August 1, 2024
Entirely new approaches with surprisingly good results have been recently discovered and published in July’s papers. Here’s what the research world has revealed this month. LEAF News Interviews Longevity Biotech
Very Old People Have Healthy Gut Bacteria
July 31, 2024
The authors of a recent review investigated what is known about gut microbiota in centenarians and how gut microbes can help people achieve extreme longevity [1]. What makes centenarians special?
A Key Pathway for Sarcopenia Reversal
July 30, 2024
In Aging Cell, researchers have published a paper on a cellular energy source that appears to be a key signaling molecule in sarcopenia. A little-explored molecule Sarcopenia, a condition that
Inflammation May Drive Fat Distribution in Older People
August 15, 2024
A new study published in Aging Cell has detailed what happens to individual fat cells in white adipose tissue (WAT) as they age. When fat is more than just fat Previous research has described WAT as an organ in its own right, functioning not only as
A Botanical Extract Extends Lifespan and Healthspan in Mice
August 14, 2024
According to a new study, a polyphenol-rich natural extract positively impacts lifespan, healthspan, and cellular senescence. These results were observed in both cell culture and a mouse model [1]. From folk medicine to modern science Traditional and folk medicines offer many botanical extracts that can be
NMN Increases Lifespan in Female Mice
August 13, 2024
A new preprint from David Sinclair’s lab has discovered that NMN supplementation started in midlife increases median and maximal lifespan in female mice and boosts healthspan in males [1]. NAD and aging Nicotinamide adenine dinucleotide (NAD) is a ubiquitous metabolite that performs several crucial roles. NAD’s
A Ketosis-Related Compound Alleviates Arthritis in Rats
August 12, 2024
In Aging Cell, researchers have published details on the pathway by which a compound commonly found in ketone bodies ameliorates osteoarthritis in a rat model. Chondrocytes are crucial in arthritis The cartilage holding joints together is built and maintained by chondrocytes, which synthesize such necessary proteins
Michael Antonov: from Oculus to Longevity Biotech
August 9, 2024
After Oculus was sold to Facebook for two billion dollars a decade ago, Michael Antonov, one of the founders, could have become a major tech investor, a popular podcaster with his own mega-theory of everything, a hedonist, or all of the above. Instead, he gravitated towards
Immune Peptide Might Keep White Blood Cells Contained
August 8, 2024
In npj Aging, researchers have described how immune cell infiltration in inflammaging can be reduced with an immune-related peptide in a mouse model. Immune cell infiltration In a previous paper, these researchers have reported that aging affects the movement of white blood cells (leukocytes) in a
Fecal Microbiota Transplants Reduce Vascular Aging in Mice
August 7, 2024
Fecal microbiota transplantation from young mice to older mice improved multiple metabolic parameters and some hallmarks of aging, such as inflammation and telomere shortening [1]. Bringing back the balance Dysbiosis, an imbalance in the gut microbiome, is a newly recognized hallmark of aging [2]. Dysbiosis elevates
Hyperbaric Oxygen Therapy Increases Fitness in Elderly
August 6, 2024
In a new study, a 12-week protocol of hyperbaric oxygen therapy (HBOT) resulted in marked increases in aerobic capacity and cardiac blood flow [1]. Building pressure HBOT involves placing patients in a tightly sealed chamber where they breathe pure oxygen under higher-than-normal atmospheric pressure. This treatment
New Epigenetic Clock Built on Lurking DNA Fragments
August 5, 2024
In Aging Cell, a team of researchers has announced Retroelement-Age, a novel clock that focuses on the expression of buried pieces of DNA that are normally suppressed. Corrupted but unexpressed The natural human genome has a large number of artifacts left over from ancient viral infections
Longevity and DeSci Recap – July 2024
August 5, 2024
The Longevity and DeSci Recap is back, and our latest edition covers high-profile events including the Longevity Investors Conference in Gstaad, new innovations in AFib monitoring, and even some celebrity-related news. This month, we’ll continue to explore the latest events, current research, and investment news to
Vegan Diet Lowers Biological Age in a New Study
August 2, 2024
In a study that involved pairs of identical twins, Stanford scientists have shown that a healthy vegan diet leads to a decrease in biological age and possibly to other health benefits [1]. Do you really live longer if you eat well? A good diet can do
Rapamycin + Trametinib Increase Mouse Lifespan by up to 35%
August 1, 2024
Combining rapamycin and trametinib seemed to have a cumulative effect in both sexes but mostly in females [1]. These results are probably due to a reduction in both cancer and inflammation. A winning combo The idea that combination treatments are the future of life extension is
Rejuvenation Roundup July 2024
August 1, 2024
Entirely new approaches with surprisingly good results have been recently discovered and published in July’s papers. Here’s what the research world has revealed this month. LEAF News Interviews Longevity Biotech Fellowship: Road To A Post-Aging Society: The Longevity Biotech Fellowship is one of the most interesting
Very Old People Have Healthy Gut Bacteria
July 31, 2024
The authors of a recent review investigated what is known about gut microbiota in centenarians and how gut microbes can help people achieve extreme longevity [1]. What makes centenarians special? One way of investigating what gives people longevity and health in older ages is to study
A Key Pathway for Sarcopenia Reversal
July 30, 2024
In Aging Cell, researchers have published a paper on a cellular energy source that appears to be a key signaling molecule in sarcopenia. A little-explored molecule Sarcopenia, a condition that increases with aging, reduces muscle mass in older people, and leads to a decreased quality of