Category: News
Nobel Prize in Medicine Goes to Two mRNA Vaccine Researchers
October 3, 2023
Katalin Karikó and Drew Weissman received this year’s Nobel Prize in Physiology or Medicine for a groundbreaking discovery that facilitated the development of mRNA vaccines and can be relevant to
NMN Reduces Systolic Blood Pressure in Clinical Trial
October 2, 2023
Combining human clinical trial research, cellular analysis, and mouse studies, researchers publishing in the Nature journal Signal Transduction and Targeted Therapy have discovered a relationship between NAD+, hypertension, and the
Rejuvenation Roundup September 2023
October 2, 2023
On some corners of the Internet, “Spooktober”, effectively a month-long Halloween, has just begun. Here at Lifespan.io, though, we talk about something scary all year long. Here’s what’s been done
Longevity and DeSci Recap – September 2023
October 2, 2023
Welcome back to the latest edition of the Longevity and DeSci Recap. Here, you’ll discover the latest interviews, insights, and research in the longevity tech sphere over the past month
Study: Waist-to-Hip Ratio Predicts Mortality Better Than BMI
September 29, 2023
A new study suggests that waist-to-hip ratio (WHR) has a more linear correlation with all-cause mortality than either body mass index (BMI) or fat mass index (FMI) and might replace
Restoring Heart Regeneration With a Metabolic Switch
September 28, 2023
In a recent article in Nature, researchers have restored cardiac regeneration to adult mice by disabling fatty acid oxidation, discovering a potential pathway for human treatments. A question of metabolism
Human Clinical Trials of NMN for Safety and Effectiveness
September 27, 2023
In a recent paper, researchers reviewed the literature for human clinical trials that address NMN’s safety and anti-aging effects [1]. The roles of NAD+ and NMN in aging NAD+ (nicotinamide
ARDD 2023: The Mother of All Longevity Conferences
September 26, 2023
Once a year, Copenhagen becomes a Mecca for the longevity community. Hundreds of people flock to the picturesque Danish capital to attend the Aging Research and Drug Discovery Meeting (ARDD)
An Unexplored Link Between Inflammation and Alzheimer’s
September 25, 2023
An article in GeroScience describes a previously unexplored relationship between FABP7, an inflammatory molecule that binds to fatty acids, and Alzheimer’s disease. Not just a transporter Originally, as the authors
Developing a Treatment for Arthritis from Stem Cell Signals
September 22, 2023
Resarchers publishing in Aging have found that extracellular vesicles (EVs) derived from human umbilical cord mesenchymal stem cells (MSCs) reduce inflammatory markers in chondrocytes, which are responsible for building and
Creating a Noise Clock to Measure Biological Age
September 21, 2023
Publishing in Aging, the Conboy research lab has outlined the problems with existing machine learning-based clocks and created a new clock based on epigenetic noise. The problem with linear regression
Senolytics as a Potential Back Pain Treatment
September 20, 2023
In a recent paper, researchers from McGill University in Canada have investigated how a combination of two senolytics, RG-7112 and o-Vanillin, influences the intervertebral disc cells of back pain patients
Exercise Mimetic Improves Memory In Old Mice
September 19, 2023
Researchers have identified a platelet-derived factor that improves cognition in mice and published their findings in Nature Communications. Finding the right molecules This paper begins with the same refrain common
Is There a Single Essence of Aging?
September 18, 2023
In the Proceedings of the National Academy of Science, Dr. Jesse Poganik and Prof. Vadim Gladyshev of Harvard Medical School have presented an opinion proposing a consensus understanding of aging.
Stem Cell Signals Improve Cardiac Health in Old Rats
September 18, 2023
The Journal Club returns with Dr. Oliver Medvedik on September 29th at 12:00 Eastern time on our Facebook page. We take a look at a recent study published in Nature,
Nobel Prize in Medicine Goes to Two mRNA Vaccine Researchers
October 3, 2023
Katalin Karikó and Drew Weissman received this year’s Nobel Prize in Physiology or Medicine for a groundbreaking discovery that facilitated the development of mRNA vaccines and can be relevant to future anti-aging therapies. A crucial discovery The COVID-19 pandemic was one of the biggest health challenges
NMN Reduces Systolic Blood Pressure in Clinical Trial
October 2, 2023
Combining human clinical trial research, cellular analysis, and mouse studies, researchers publishing in the Nature journal Signal Transduction and Targeted Therapy have discovered a relationship between NAD+, hypertension, and the immune signal CD38. A vital component in metabolic function This research begins with a discussion of
Rejuvenation Roundup September 2023
October 2, 2023
On some corners of the Internet, “Spooktober”, effectively a month-long Halloween, has just begun. Here at Lifespan.io, though, we talk about something scary all year long. Here’s what’s been done to fight aging last month. LEAF News EARD2023 Ending Age-Related Diseases 2023: Longevity/DeSci Success: The Ending
Longevity and DeSci Recap – September 2023
October 2, 2023
Welcome back to the latest edition of the Longevity and DeSci Recap. Here, you’ll discover the latest interviews, insights, and research in the longevity tech sphere over the past month and learn more about topics including blockchain, DAOs, cryptocurrency, DeSci, and related events. This September marked
Study: Waist-to-Hip Ratio Predicts Mortality Better Than BMI
September 29, 2023
A new study suggests that waist-to-hip ratio (WHR) has a more linear correlation with all-cause mortality than either body mass index (BMI) or fat mass index (FMI) and might replace BMI as a metric of choice [1]. Is BMI good enough? Comparing total mass to height,
Restoring Heart Regeneration With a Metabolic Switch
September 28, 2023
In a recent article in Nature, researchers have restored cardiac regeneration to adult mice by disabling fatty acid oxidation, discovering a potential pathway for human treatments. A question of metabolism As heart muscle cells (myocytes) mature, they make a metabolic switch from glycolysis to the oxidation
Human Clinical Trials of NMN for Safety and Effectiveness
September 27, 2023
In a recent paper, researchers reviewed the literature for human clinical trials that address NMN’s safety and anti-aging effects [1]. The roles of NAD+ and NMN in aging NAD+ (nicotinamide adenine dinucleotide) is a molecule essential in such processes as metabolism, cell death, aging, DNA repair,
ARDD 2023: The Mother of All Longevity Conferences
September 26, 2023
Once a year, Copenhagen becomes a Mecca for the longevity community. Hundreds of people flock to the picturesque Danish capital to attend the Aging Research and Drug Discovery Meeting (ARDD) for five full days of talks by geroscientists and biotech leaders, mingling and networking with like-minded
An Unexplored Link Between Inflammation and Alzheimer’s
September 25, 2023
An article in GeroScience describes a previously unexplored relationship between FABP7, an inflammatory molecule that binds to fatty acids, and Alzheimer’s disease. Not just a transporter Originally, as the authors explain, fatty acid binding proteins (FABPs) were considered to be simple biological chaperones that did not
Developing a Treatment for Arthritis from Stem Cell Signals
September 22, 2023
Resarchers publishing in Aging have found that extracellular vesicles (EVs) derived from human umbilical cord mesenchymal stem cells (MSCs) reduce inflammatory markers in chondrocytes, which are responsible for building and maintaining human cartilage. An established approach This is far from the first attempt at treating osteoarthritis
Creating a Noise Clock to Measure Biological Age
September 21, 2023
Publishing in Aging, the Conboy research lab has outlined the problems with existing machine learning-based clocks and created a new clock based on epigenetic noise. The problem with linear regression This paper begins with a description of the elastic net, an artificial intelligence algorithm that powers
Senolytics as a Potential Back Pain Treatment
September 20, 2023
In a recent paper, researchers from McGill University in Canada have investigated how a combination of two senolytics, RG-7112 and o-Vanillin, influences the intervertebral disc cells of back pain patients [1]. Back pain is a widespread issue An overwhelming majority of people, a full 80%, have
Exercise Mimetic Improves Memory In Old Mice
September 19, 2023
Researchers have identified a platelet-derived factor that improves cognition in mice and published their findings in Nature Communications. Finding the right molecules This paper begins with the same refrain common in discussions about the biological effects of exercise: the inability of some older people to conduct
Is There a Single Essence of Aging?
September 18, 2023
In the Proceedings of the National Academy of Science, Dr. Jesse Poganik and Prof. Vadim Gladyshev of Harvard Medical School have presented an opinion proposing a consensus understanding of aging. A problem of focus and funding The authors lament a lack of focus and funding in
Stem Cell Signals Improve Cardiac Health in Old Rats
September 18, 2023
The Journal Club returns with Dr. Oliver Medvedik on September 29th at 12:00 Eastern time on our Facebook page. We take a look at a recent study published in Nature, in which extracellular vesicles derived from neonatal cardiac progenitors produced significant rejuvenation in old rats and