Category: News

Egg cell

Spermidine May Improve Egg Health and Fertility

Reporters publishing in Nature Aging have identified a metabolite that appears to restore the age-related loss of quality of egg cells (oocytes) in mice. Spermidine is not just for sperm

Overcoming Age-Related Diseases

Help Us Solve Aging With Cryptocurrency

  If you want to contribute to Lifespan.io and use cryptocurrency, there is a great opportunity happening right now to support our work! Donate to help us solve aging We

Dublin Longevity Declaration

Dublin Longevity Declaration Off to a Good Start

The Dublin Longevity Declaration, an unprecedented initiative that aims to change humanity’s perception of aging, is scooping signatures at a record pace. The need for a paradigm shift Last August,

Centenarian Cake

Blood Biomarkers as Predictors of Longevity

A recent study’s authors investigated whether biomarkers measured earlier in life can predict if someone will live to their 100th birthday [1]. 35-year-long centenarian study Previous research has found that

Blood pressure

NMN Reduces Systolic Blood Pressure in Clinical Trial

Combining human clinical trial research, cellular analysis, and mouse studies, researchers publishing in the Nature journal Signal Transduction and Targeted Therapy have discovered a relationship between NAD+, hypertension, and the

Longevity Summit Dublin Logo

The Longevity World Meets in Dublin for a Second Time

Last year’s inaugural Longevity Summit Dublin conference was a good start. Its second iteration, held in August this year, was universally acclaimed for being even bigger and better. Just like the last time, this conference was marked by a considerable presence of longevity advocates alongside scientists

Egg cell

Spermidine May Improve Egg Health and Fertility

Reporters publishing in Nature Aging have identified a metabolite that appears to restore the age-related loss of quality of egg cells (oocytes) in mice. Spermidine is not just for sperm While it was originally found in semen, the metabolite spermidine has been found in many different

Cells and DNA

Study Suggests a New Mechanism of Cellular Senescence

Scientists have found that leakage of mitochondrial DNA in senescent cells is a major cause of their pro-inflammatory activity, and it can be targeted without clearing those cells out [1]. A new aspect of senescence Clearing senescent cells with drugs called senolytics is one of the

Animal husbandry

Why Long-Lived Animals Are Needed for Life Extension Studies

A team of researchers, including Matt Kaeberlein and Brian Kennedy, has published a preprint discussing the necessity of using long-lived animals in life extension research. The Interventions Testing Program (ITP) uncovers weaknesses The ITP is run by the National Institutes of Aging and described by these

Omega 3 Sources

Correlations Between Omega-3 Fatty Acids and Brain Function

The authors of a study published in Brain Sciences have investigated the relationship between omega-3 fatty acid levels, brain volume, and cognitive function [1]. Aging and changes in the brain With aging comes progressive changes in brain structure and ra eduction in cognitive abilities. The first changes

The Journal Club is a monthly livestream hosted by Dr. Oliver Medvedik which covers the latest aging research papers.

Journal Club October 2023 with Irina and Mike Conboy

The Journal Club returns on Friday October 27th at 11:30 am Eastern time on the Lifespan.io Facebook page.  We will be discussing the new paper from Conboy et al. which examines current DNA methylation clocks and their limitations in the context of aging. They also developed

Overcoming Age-Related Diseases

Help Us Solve Aging With Cryptocurrency

  If you want to contribute to Lifespan.io and use cryptocurrency, there is a great opportunity happening right now to support our work! Donate to help us solve aging We promote the advancement of medical technologies that will increase healthy human longevity. By sponsoring, democratizing, and

Long-tailed Macaque

SIRT2 Works Against Cardiac Aging in Mice and Monkeys

Working with non-human primates, scientists have discovered that the protein SIRT2, a member of the sirtuin family, might play an important role in slowing cardiac aging [1]. The heart of the matter The heart is arguably the hardest worker among the organs, constantly pumping enormous amounts

Mouse in Maze

A Mutation Rejuvenates Memory in Worms and Mice

A study published in Cell Reports has shown how the activation of a common protein in neurons improves memory in both worms and mammals. Common between animals This paper begins with a striking fact: C.elegans worms, mice, and people all lose memory with age [1] and

Dublin Longevity Declaration

Dublin Longevity Declaration Off to a Good Start

The Dublin Longevity Declaration, an unprecedented initiative that aims to change humanity’s perception of aging, is scooping signatures at a record pace. The need for a paradigm shift Last August, hundreds of longevity enthusiasts, from certified geroscience stars to graduate students, gathered in Dublin for the

Stem Cells for the Knee

Improving Quality and Length of Life with Stem Cells

A review article published in Stem Cell Research & Therapy has described the ways in which mesenchymal stromal cells (MSCs) are being developed to treat diseases, including age-related diseases. A lack of clinical treatments The reviewers begin their paper by discussing the most common age-related diseases.

Lifespan io Editorial

Decentralized Science is Key to Funding Aging Research

Autumn is upon those of us in the Northern Hemisphere. A lot has happened, and as usual, we have been busy supporting human longevity research to end age-related diseases. The first talks from EARD2023 are available The Ending Age-Related Diseases 2023 (EARD2023) conference is over, and

Centenarian Cake

Blood Biomarkers as Predictors of Longevity

A recent study’s authors investigated whether biomarkers measured earlier in life can predict if someone will live to their 100th birthday [1]. 35-year-long centenarian study Previous research has found that people who become centenarians have fewer disabilities, comorbidities, and hospitalizations earlier in life. They are also

Kariko Weissmann

Nobel Prize in Medicine Goes to Two mRNA Vaccine Researchers

Katalin Karikó and Drew Weissman received this year’s Nobel Prize in Physiology or Medicine for a groundbreaking discovery that facilitated the development of mRNA vaccines and can be relevant to future anti-aging therapies. A crucial discovery The COVID-19 pandemic was one of the biggest health challenges

Blood pressure

NMN Reduces Systolic Blood Pressure in Clinical Trial

Combining human clinical trial research, cellular analysis, and mouse studies, researchers publishing in the Nature journal Signal Transduction and Targeted Therapy have discovered a relationship between NAD+, hypertension, and the immune signal CD38. A vital component in metabolic function This research begins with a discussion of