Category: News
Nicotinamide Riboside Improves Muscle Energy in Trial
February 17, 2023
Scientists have shown that long-term treatment with a popular NAD+ precursor can raise NAD+ levels in blood and muscle and increase mitochondria content and function [1]. Twin-based design NAD+ is
Human Organoids for Brain Regeneration
February 16, 2023
Researchers publishing in Cell Stem Cell have used organoids derived from human cells to regrow the brain tissue of rats. The need to repair permanent damage While human beings do
Young Ovarian Tissue Rejuvenates Old Mice
February 15, 2023
In a paper published in Frontiers in Endocrinology, researchers have shown that transplanted young ovarian tissue improves the immune function of old recipient mice even if they are hormone-depleted [1].
Lithium Is Linked to Lower Mortality
February 14, 2023
In an epidemiological study published in Aging, scientists have shown that patients who take lithium have much lower all-cause mortality than patients on other psychotropic drugs [1]. Is lithium a
The Link Between NAD+ and Heart Failure
February 13, 2023
A paper published today in Nature Cardiovascular Research has explained a relationship between dilated cardiac myopathy (DCM), epigenetic dysregulation, NAD+, and the epigenetic regulatory molecule Kdm8. A gradual decline of
Meet hack-age, Winners of the January 2023 LongHack
February 10, 2023
On January 22nd, hack-age won the 2023 LongHack competition, which carried a grand prize of 5,500 VITA and 3,500 USD. lifespan.io caught up with the team behind the winning project
Extracellular Vesicles for Tendon Healing
February 9, 2023
Researchers publishing in Journal of Nanobiotechnology have found that extracellular vesicles derived from young cells are effective in treating a model of a common tendon disease. Tendinopathy and stem cells
Viral Exposure Might Increase the Risk of Neurodegeneration
February 8, 2023
In a paper published in Neuron, researchers have shown an association between exposure to various viruses and an increased risk of several neurodegenerative diseases, including Alzheimer’s and Parkinson’s diseases [1].
Retroviruses Contribute to the Spread of Cellular Senescence
February 7, 2023
Scientists have found that the remnants of the ancient retrovirus family HERVK, which reside in our genome, are transcribed more frequently in aged cells. This is caused by cellular senescence
Diagnosing Alzheimer’s in the Near Infrared
February 6, 2023
In Nature Biomedical Engineering, a team of researchers has published an innovative method of making tau tangles and amyloid beta visible in the near infrared, allowing doctors and researchers to
Is Increasing Human Lifespan Unnatural?
February 5, 2023
Whenever the topic of any possible increased healthy longevity through science is discussed, a common objection to developing the technology is that it is unnatural. This argument usually arises during
Senolytic Improves Metabolism in Mice
February 3, 2023
Scientists have shown that a popular senolytic combination of dasatinib and quercetin improves glucose tolerance and fasting blood glucose levels in aged mice [1]. The question of metabolism Cellular senescence
Photosensitive Drug Clears Senescent Cells
February 2, 2023
Research published in Nature Aging has shown that a photosensitive senolytic drug can be used to selectively remove senescent cells, slowing functional organ aging in mice. A problem of delivery
Ultrasound Rejuvenates Senescent Cells Through Autophagy
February 1, 2023
In a preprint paper, the researchers have shown that low-frequency ultrasound treatment decreases senescence and improves the physical performance of aged mice [1]. Mechanical approach Cellular senescence, the inability of
Rejuvenation Roundup January 2023
February 1, 2023
As 2023 continues, so does new research into rejuvenation, regeneration, and restoration. Let’s see what’s been done to reverse age-related diseases in January. lifespan.io News Team and activities New Year,
Nicotinamide Riboside Improves Muscle Energy in Trial
February 17, 2023
Scientists have shown that long-term treatment with a popular NAD+ precursor can raise NAD+ levels in blood and muscle and increase mitochondria content and function [1]. Twin-based design NAD+ is an important coenzyme that performs multiple functions, including mitochondrial energy production. NAD+ levels decrease with aging,
Human Organoids for Brain Regeneration
February 16, 2023
Researchers publishing in Cell Stem Cell have used organoids derived from human cells to regrow the brain tissue of rats. The need to repair permanent damage While human beings do generate new neurons (neurogenesis) [1], this ability is very limited, in both region and amount. Brain
Young Ovarian Tissue Rejuvenates Old Mice
February 15, 2023
In a paper published in Frontiers in Endocrinology, researchers have shown that transplanted young ovarian tissue improves the immune function of old recipient mice even if they are hormone-depleted [1]. Not just a reproductive matter Although women generally live longer than men, women spend almost half
Lithium Is Linked to Lower Mortality
February 14, 2023
In an epidemiological study published in Aging, scientists have shown that patients who take lithium have much lower all-cause mortality than patients on other psychotropic drugs [1]. Is lithium a longevity drug? Lithium has long been prescribed for certain psychiatric conditions, mainly bipolar disorder. With time,
The Link Between NAD+ and Heart Failure
February 13, 2023
A paper published today in Nature Cardiovascular Research has explained a relationship between dilated cardiac myopathy (DCM), epigenetic dysregulation, NAD+, and the epigenetic regulatory molecule Kdm8. A gradual decline of ability DCM occurs when the left ventricle of the heart becomes enlarged and loses its ability
Meet hack-age, Winners of the January 2023 LongHack
February 10, 2023
On January 22nd, hack-age won the 2023 LongHack competition, which carried a grand prize of 5,500 VITA and 3,500 USD. lifespan.io caught up with the team behind the winning project to learn more about their idea and their experience competing in the hackathon. What is LongHack?
Extracellular Vesicles for Tendon Healing
February 9, 2023
Researchers publishing in Journal of Nanobiotechnology have found that extracellular vesicles derived from young cells are effective in treating a model of a common tendon disease. Tendinopathy and stem cells Swelling, weakness, tenderness, and tendon pain during activities are the characteristic symptoms of chronic tendinopathy [1],
Viral Exposure Might Increase the Risk of Neurodegeneration
February 8, 2023
In a paper published in Neuron, researchers have shown an association between exposure to various viruses and an increased risk of several neurodegenerative diseases, including Alzheimer’s and Parkinson’s diseases [1]. Roots of neurodegeneration There are many causes underlying neurodegeneration, such as genetic predisposition, toxin exposure, poor
Retroviruses Contribute to the Spread of Cellular Senescence
February 7, 2023
Scientists have found that the remnants of the ancient retrovirus family HERVK, which reside in our genome, are transcribed more frequently in aged cells. This is caused by cellular senescence and accelerates it, including in the neighboring cells, when those are infected by retroviral particles [1].
Diagnosing Alzheimer’s in the Near Infrared
February 6, 2023
In Nature Biomedical Engineering, a team of researchers has published an innovative method of making tau tangles and amyloid beta visible in the near infrared, allowing doctors and researchers to see through bone with relatively simple equipment. Current methods are difficult There are three main approaches
Is Increasing Human Lifespan Unnatural?
February 5, 2023
Whenever the topic of any possible increased healthy longevity through science is discussed, a common objection to developing the technology is that it is unnatural. This argument usually arises during discussions of therapies that directly address the various processes of aging, and it is important to understand their basis
Senolytic Improves Metabolism in Mice
February 3, 2023
Scientists have shown that a popular senolytic combination of dasatinib and quercetin improves glucose tolerance and fasting blood glucose levels in aged mice [1]. The question of metabolism Cellular senescence is one of the hallmarks of aging, and senolytics, drugs that clear away senescent cells, have
Photosensitive Drug Clears Senescent Cells
February 2, 2023
Research published in Nature Aging has shown that a photosensitive senolytic drug can be used to selectively remove senescent cells, slowing functional organ aging in mice. A problem of delivery The researchers name three problems with senolytic drugs: specificity to senescent cells (accuracy), controllability of administration
Ultrasound Rejuvenates Senescent Cells Through Autophagy
February 1, 2023
In a preprint paper, the researchers have shown that low-frequency ultrasound treatment decreases senescence and improves the physical performance of aged mice [1]. Mechanical approach Cellular senescence, the inability of aged cells to divide while still being metabolically active, is one of the hallmarks of aging.
Rejuvenation Roundup January 2023
February 1, 2023
As 2023 continues, so does new research into rejuvenation, regeneration, and restoration. Let’s see what’s been done to reverse age-related diseases in January. lifespan.io News Team and activities New Year, Same Goal to End Age-Related Diseases: The new year is well underway, and we have been