Category: News
Gene Therapy for Heart Regeneration in Living Animals
January 30, 2023
Research published in Cell Stem Cell has described how previously unmodified animals have been given regenerative abilities akin to those of zebrafish, restoring their heart muscle after injury. A TREE
New Way to Help Aging Cells Produce Collagen
January 27, 2023
Scientists have demonstrated that extracellular vesicles loaded with mRNA coding for collagen production can be easily produced and delivered into aging fibroblasts in vitro and in vivo, boosting collagen levels
Brain Aging on a Small, Physical Level
January 26, 2023
A new publication in Nature Aging has explained a great deal about aging of the neurovascular system, showing where and how the brain’s blood supply changes with aging in a
Eric Verdin on the Buck, Nutrition, and Ketosis
January 26, 2023
Six years ago, Dr. Eric Verdin, already a highly acclaimed veteran geroscientist, was catapulted to the forefront of the field when he agreed to lead the Buck Institute for Research
New Year, Same Goal to End Age-Related Diseases
January 26, 2023
The new year is well underway, and we have been our usual busy selves. Join us for the first editorial of the year, and find out about the awesome things
Caloric Restriction Does Not Extend Lifespan in Every Model
January 25, 2023
In a preprint paper, researchers have evaluated the effect of caloric restriction on two long-lived planarian species in various environments that mimic the stochasticity of the real world [1]. Does
Partial Reprogramming Extends Lifespan in Old Mice
January 25, 2023
The journal club returns on Tuesday 31st January at 12:00 Eastern on our Facebook page with host Dr. Oliver Medvedik. We are looking at a preprint this time where partial
Journal Club January 2023
January 25, 2023
The journal club returns on Tuesday 31st January at 12:00 Eastern on our Facebook page with host Dr. Oliver Medvedik. We are looking at a preprint this time where partial
NMN Reduces Metastasis in Difficult Breast Cancer Model
January 24, 2023
In a new paper published in Nature, scientists have found that raising NAD+ levels via supplementation with nicotinamide mononucleotide (NMN) activates SIRT1 to dampen metastasis in mouse TNBC models [1].
Allogeneic CAR-T Cells Complete Phase 1 Trial
January 23, 2023
The results of a Phase 1 clinical trial of allogeneic CAR T cell therapy against multiple myeloma have been published today in Nature Medicine, and they appear to be promising.
Senescent Cells Leave Fragments Attached to Other Cells
January 20, 2023
In a preprint paper, scientists have reported that senescent cells transiently adhere to neighboring cells, and, upon departure, leave in place large membrane-enclosed fragments of themselves [1]. Mysterious fragments Cellular
Exploring the Biological Aging Advice in “Younger You”
January 20, 2023
Dr. Kara Fitzgerald’s new book provides an evidence-based approach to diet and lifestyle that aims to reduce your biological age. Beginning with epigenetics Younger You offers a pragmatic and easily
Introducing A Longevity Hackathon for Accelerating Research
January 20, 2023
The latest hackathon event, LongHack, hosted by the VitaDAO team beginning today and continuing over the weekend, will focus on discovering new approaches to longevity science and inspiring new initiatives
The APOE4 Gene Is Associated With Worse Stroke Outcomes
January 19, 2023
Researchers publishing in Aging have found that there is a correlation between the APOE4 gene and poor outcomes after ischemic stroke. An allele with a long and sordid history Other
Selfish, Reckless, Satanic: Life Extension in Movies
January 19, 2023
In the much-awaited sequel to the movie Avatar, there is a passing, peculiar mention of life extension. This mention, as can be expected, is negative. In the movie, the greedy,
Gene Therapy for Heart Regeneration in Living Animals
January 30, 2023
Research published in Cell Stem Cell has described how previously unmodified animals have been given regenerative abilities akin to those of zebrafish, restoring their heart muscle after injury. A TREE of life This study is introduced with a discussion of gene therapy as a field, noting
New Way to Help Aging Cells Produce Collagen
January 27, 2023
Scientists have demonstrated that extracellular vesicles loaded with mRNA coding for collagen production can be easily produced and delivered into aging fibroblasts in vitro and in vivo, boosting collagen levels and eliminating signs of skin aging in mice [1]. Superior delivery method Finding a good way
Brain Aging on a Small, Physical Level
January 26, 2023
A new publication in Nature Aging has explained a great deal about aging of the neurovascular system, showing where and how the brain’s blood supply changes with aging in a mouse model. A branching network of blood vessels In the neurovascular system, arteries lead to arterioles,
Eric Verdin on the Buck, Nutrition, and Ketosis
January 26, 2023
Six years ago, Dr. Eric Verdin, already a highly acclaimed veteran geroscientist, was catapulted to the forefront of the field when he agreed to lead the Buck Institute for Research on Aging (or simply “the Buck”), a renowned research institution based in Novato, CA. We talked
New Year, Same Goal to End Age-Related Diseases
January 26, 2023
The new year is well underway, and we have been our usual busy selves. Join us for the first editorial of the year, and find out about the awesome things we have been doing for longer, healthier lives. Decentralized science could support aging research progress Lifespan.io
Caloric Restriction Does Not Extend Lifespan in Every Model
January 25, 2023
In a preprint paper, researchers have evaluated the effect of caloric restriction on two long-lived planarian species in various environments that mimic the stochasticity of the real world [1]. Does the theory hold? According to a theory that is largely based on plentiful data from model
Partial Reprogramming Extends Lifespan in Old Mice
January 25, 2023
The journal club returns on Tuesday 31st January at 12:00 Eastern on our Facebook page with host Dr. Oliver Medvedik. We are looking at a preprint this time where partial reprogramming factors were used to reverse some aspects of aging in old mice. The paper is
Journal Club January 2023
January 25, 2023
The journal club returns on Tuesday 31st January at 12:00 Eastern on our Facebook page with host Dr. Oliver Medvedik. We are looking at a preprint this time where partial reprogramming factors were used to reverse some aspects of aging in old mice. The paper is
NMN Reduces Metastasis in Difficult Breast Cancer Model
January 24, 2023
In a new paper published in Nature, scientists have found that raising NAD+ levels via supplementation with nicotinamide mononucleotide (NMN) activates SIRT1 to dampen metastasis in mouse TNBC models [1]. A double-edged sword NAD+ is a ubiquitous co-enzyme that facilitates numerous processes in our body, from
Allogeneic CAR-T Cells Complete Phase 1 Trial
January 23, 2023
The results of a Phase 1 clinical trial of allogeneic CAR T cell therapy against multiple myeloma have been published today in Nature Medicine, and they appear to be promising. B cells, engineered T cells, and lymphodepletion Multiple myeloma is a cancer of the plasma B
Senescent Cells Leave Fragments Attached to Other Cells
January 20, 2023
In a preprint paper, scientists have reported that senescent cells transiently adhere to neighboring cells, and, upon departure, leave in place large membrane-enclosed fragments of themselves [1]. Mysterious fragments Cellular senescence is central to aging, but there are still a lot of unknowns around this complex
Exploring the Biological Aging Advice in “Younger You”
January 20, 2023
Dr. Kara Fitzgerald’s new book provides an evidence-based approach to diet and lifestyle that aims to reduce your biological age. Beginning with epigenetics Younger You offers a pragmatic and easily understood primer on the role of epigenetics and aging along with an exquisitely detailed plan for
Introducing A Longevity Hackathon for Accelerating Research
January 20, 2023
The latest hackathon event, LongHack, hosted by the VitaDAO team beginning today and continuing over the weekend, will focus on discovering new approaches to longevity science and inspiring new initiatives in the field. What is LongHack? LongHack is a longevity-focused hackathon that is hosted by VitaDAO
The APOE4 Gene Is Associated With Worse Stroke Outcomes
January 19, 2023
Researchers publishing in Aging have found that there is a correlation between the APOE4 gene and poor outcomes after ischemic stroke. An allele with a long and sordid history Other than its well-known association with Alzheimer’s disease, the APOE4 allele, which codes for the ApoE4 apolipoprotein
Selfish, Reckless, Satanic: Life Extension in Movies
January 19, 2023
In the much-awaited sequel to the movie Avatar, there is a passing, peculiar mention of life extension. This mention, as can be expected, is negative. In the movie, the greedy, nature-destroying humans hunt a local whale-like species for several ounces of precious liquid secreted by the