Category: News
Carotid Bodies Play a Role in Glucose Regulation
March 2, 2022
An advance online preprint was recently released in Circulation Research examining carotid bodies’ role in hypertension and diabetes [1]. It will be published in the journal later this week. Drugs
Chloroquine Increases Maximum Lifespan in Rats by 13%
March 1, 2022
Scientists have shown that chloroquine, a well-known anti-malarial drug and the cousin of hydroxychloroquine, attenuates inflammation and fibrosis while significantly extending median and maximum lifespan in naturally aged rats [1].
Rejuvenation Roundup February 2022
March 1, 2022
February might be the shortest month, but it’s still full of exciting research on the path towards ending age-related diseases, including senolytics and new ways of looking at epigenetics. Let’s
Combining Epigenetic and Imaging Biomarkers
February 28, 2022
Cardiologists, epidemiologists, and other researchers publishing in Aging have discovered that epigenetic aging and brain scans can be combined to accurately predict cognitive decline. Two entirely different measurements The ongoing
Resveratrol Ameliorates Erectile Dysfunction in Old Rats
February 25, 2022
Scientists have shown that resveratrol rescues erectile function in aged rats, most probably by activating SIRT1, and that it can work in synergy with the existing erectile dysfunction treatment tadalafil
The Effects of Early Life Rapamycin Administration on Mice
February 24, 2022
A team of researchers, including Steve Horvath, Leonid Peshkin, and Vadim Gladyshev, has published a preprint on bioRxiv showing the effects of early administration of rapamycin over the lifespans of
Urolithin A Affects Muscle and Mitochondria in Older Adults
February 23, 2022
A study published in the Journal of the American Medical Association has examined the dosage and safety of a urolithin A supplement [1]. This study also examined urolithin A‘s effect
NAD+ Levels Are Correlated with Physical Activity in Humans
February 22, 2022
In a study published in Nature Aging, a group of scientists has shown that NAD+ levels are correlated not only with age but with physical activity, with elder athletes rivaling
Dr. Pankaj Kapahi: “AGEs are a Trillion-Dollar Industry”
February 22, 2022
Dr. Pankaj Kapahi is a veteran geroscientist. His laboratory at the famous Buck Institute for Research on Aging is among the few that study advanced glycation end products (AGEs) and
A New Understanding of Telomere Attrition
February 21, 2022
In Nature Cell Biology, a team of researchers has presented a current review of telomeres and how they relate to aging, reflecting modern research into a decades-old topic. Telomeres and
Life Noggin Joins the lifespan.io Family
February 21, 2022
Today, we are delighted to officially announce that the popular pop-sci Youtube channel, Life Noggin, has joined the Lifespan.io family. To celebrate the official launch, we are pleased to reveal
Caloric Restriction Promotes Rejuvenation in Human Trials
February 18, 2022
In a new paper, Yale scientists present encouraging data from an unprecedented human study of caloric restriction, a powerful anti-aging intervention [1]. Eat less, live more Despite all the might
A Fresh Examination of Epigenetic Clocks
February 17, 2022
In a preprint published in bioRxiv, Morgan Levine and colleagues have identified and grouped 5,717 epigenetic CpG sites into 12 different modules, conducting an in-depth examination into how epigenetic clocks
Muscular Oxidative Capacity Predicts Mobility Decline
February 16, 2022
Researchers publishing in Aging Cell have shown a relationship between mitochondrial dysfunction and mobility decline in older adults. A changing longitudinal study Since 1958, a team of researchers from the
New Treatment for Osteoarthritis Proposed
February 15, 2022
In a paper published in Nature Aging, a group of scientists outlines a previously unknown pathway that leads to osteoarthritis and describes a promising treatment [1]. Less than a killer,
Carotid Bodies Play a Role in Glucose Regulation
March 2, 2022
An advance online preprint was recently released in Circulation Research examining carotid bodies’ role in hypertension and diabetes [1]. It will be published in the journal later this week. Drugs that target the glucagon-like peptide 1 (GLP1) receptor are widely used to treat type 2 diabetes
Chloroquine Increases Maximum Lifespan in Rats by 13%
March 1, 2022
Scientists have shown that chloroquine, a well-known anti-malarial drug and the cousin of hydroxychloroquine, attenuates inflammation and fibrosis while significantly extending median and maximum lifespan in naturally aged rats [1]. Fighting malaria since 1934 Chloroquine (CQ) was developed back in 1934 as an anti-malarial treatment and as
Rejuvenation Roundup February 2022
March 1, 2022
February might be the shortest month, but it’s still full of exciting research on the path towards ending age-related diseases, including senolytics and new ways of looking at epigenetics. Let’s see what’s happened in these four weeks. LEAF News Life Noggin Joins the Lifespan.io Family: Today,
Combining Epigenetic and Imaging Biomarkers
February 28, 2022
Cardiologists, epidemiologists, and other researchers publishing in Aging have discovered that epigenetic aging and brain scans can be combined to accurately predict cognitive decline. Two entirely different measurements The ongoing CARDIA study was started in 1985 to monitor coronary artery risk development in young adults (who
Resveratrol Ameliorates Erectile Dysfunction in Old Rats
February 25, 2022
Scientists have shown that resveratrol rescues erectile function in aged rats, most probably by activating SIRT1, and that it can work in synergy with the existing erectile dysfunction treatment tadalafil [1]. A molecule of discord Resveratrol, a plant-derived chemical of the polyphenol family, was once considered
The Effects of Early Life Rapamycin Administration on Mice
February 24, 2022
A team of researchers, including Steve Horvath, Leonid Peshkin, and Vadim Gladyshev, has published a preprint on bioRxiv showing the effects of early administration of rapamycin over the lifespans of mice. Rapamycin before and after weaning In this placebo-controlled experiment, the researchers selected the UMHET3 strain
Urolithin A Affects Muscle and Mitochondria in Older Adults
February 23, 2022
A study published in the Journal of the American Medical Association has examined the dosage and safety of a urolithin A supplement [1]. This study also examined urolithin A‘s effect on muscle endurance and specific health biomarkers. A randomized, controlled clinical trial This study is a
NAD+ Levels Are Correlated with Physical Activity in Humans
February 22, 2022
In a study published in Nature Aging, a group of scientists has shown that NAD+ levels are correlated not only with age but with physical activity, with elder athletes rivaling normal young adults [1]. NAD: small, crucial, age-related Nicotinamide adenine dinucleotide (NAD) is as important as
Dr. Pankaj Kapahi: “AGEs are a Trillion-Dollar Industry”
February 22, 2022
Dr. Pankaj Kapahi is a veteran geroscientist. His laboratory at the famous Buck Institute for Research on Aging is among the few that study advanced glycation end products (AGEs) and the many ways in which they affect aging. Dr. Kapahi’s company, Juvify, produces GLYLO, a supplement
A New Understanding of Telomere Attrition
February 21, 2022
In Nature Cell Biology, a team of researchers has presented a current review of telomeres and how they relate to aging, reflecting modern research into a decades-old topic. Telomeres and cellular senescence This paper touches upon senescent cells and the senescence-associated secretory phenotype (SASP) that they
Life Noggin Joins the lifespan.io Family
February 21, 2022
Today, we are delighted to officially announce that the popular pop-sci Youtube channel, Life Noggin, has joined the Lifespan.io family. To celebrate the official launch, we are pleased to reveal a new episode of Life Noggin that focuses on some unexpected sources of life extension that
Caloric Restriction Promotes Rejuvenation in Human Trials
February 18, 2022
In a new paper, Yale scientists present encouraging data from an unprecedented human study of caloric restriction, a powerful anti-aging intervention [1]. Eat less, live more Despite all the might of today’s science, simple lifestyle choices are still the clearest option for living longer and healthier.
A Fresh Examination of Epigenetic Clocks
February 17, 2022
In a preprint published in bioRxiv, Morgan Levine and colleagues have identified and grouped 5,717 epigenetic CpG sites into 12 different modules, conducting an in-depth examination into how epigenetic clocks work. What is a CpG site? Methylation cannot occur everywhere in the genome. The researchers explain
Muscular Oxidative Capacity Predicts Mobility Decline
February 16, 2022
Researchers publishing in Aging Cell have shown a relationship between mitochondrial dysfunction and mobility decline in older adults. A changing longitudinal study Since 1958, a team of researchers from the National Institute on Aging Intramural Research program has been conducting the Baltimore Longitudinal Study of Aging
New Treatment for Osteoarthritis Proposed
February 15, 2022
In a paper published in Nature Aging, a group of scientists outlines a previously unknown pathway that leads to osteoarthritis and describes a promising treatment [1]. Less than a killer, more than a nuisance There are plenty of deadly age-related diseases, and then there are others