Category: Biology of Aging
ChromaDex $25 Million Sale of Common Stock
February 24, 2021
ChromaDex has recently announced that it has agreed a securities purchase agreement for the sale of $25 million of its common stock in a private placement. The private placement was
Longevity Pharmacology has Come of Age
February 24, 2021
A bold feature article published in Drug Discovery Today illustrates the coming of age of longevity pharmacology. Dr. João Pedro de Magalhães, one of the biggest names in longevity research,
SIRT3 Replenishment Reverses Lung Fibrosis in Mice
February 23, 2021
Scientists have successfully reversed persistent lung fibrosis in mice by overexpressing the SIRT3 protein in lung macrophages [1]. Fibrosis: not knowing when to stop Fibrosis may be the true apex
Humacyte in Deal to Develop Prosthetic Vasculature
February 22, 2021
Tissue engineering company Humacyte is about to make a special purpose acquisition company (SPAC) deal in order to go public. The company is developing bioengineered Human Acellular Vessels (HAVs), which
Atrophy of the Neuronal Circadian Clock Is a Disease of Aging
February 19, 2021
Today, researcher Victor Bjoerk talks us through his latest published paper, in which he describes a neurodegenerative disease that affects the circadian clock. A circadian clock disease With aging, the
The NIA Is Funding Clinical Trials Against Aging
February 18, 2021
The National Institutes of Aging in the United States, a component of the National Institutes of Health, is funding clinical trials for interventions that directly affect the root causes of
Replacing Aging With Jean Hébert
February 17, 2021
Replacing Aging by Jean Hébert is the latest longevity book published for public consumption. While books such as these seem to be coming out more regularly, readers who have already
Lessons from Longevity Therapeutics 2021 – Part 4
February 16, 2021
This is the final installment in our coverage of Longevity Therapeutics 2021, a conference that brought together some of the biggest names in longevity research. Read the previous parts here,
Developing Our Ethics Code of Longevity Journalism
February 16, 2021
When lifespan.io was started in 2014 as a crowdfunding platform, we didn’t really know that we would become a news outlet covering longevity research. We didn’t plan to be one.
Proposing Gerobiotics as a New Gut Microbiome Research Field
February 15, 2021
The aging of the microbiome, the collective bacteria, fungi, protozoa and viruses that live on and inside our bodies, has become a popular research topic in recent years. The microbiome
The Intertwined Nature of NAD+, CD38, and Senescence
February 12, 2021
Aging is a multifactorial and complex process; indeed, it is probably the most complex disorder known. It is made up of a combination of dozens of malfunctions locked together in
Male and Female Gut Microbiomes Converge With Age
February 11, 2021
While the gut microbiomes of young men and women are distinct, that difference disappears in older people, according to a new study. These findings add to the growing pool of
Senescent Cells in the Aging Retina
February 8, 2021
A review published in the Journal of Neuroinflammation explores the potential application of senotherapies, particularly in the context of treating age-related macular degeneration [1]. Introducing cellular senescence One of the
Increasing NAD+ Reduces Amyloids and Benefits Mitochondria
February 5, 2021
Aging is accompanied by the loss of proteostasis, the accumulation of misfolded proteins and their amyloid aggregates, and mitochondrial dysfunction, which is partially characterized by the loss of mitochondrial homeostasis,
lifespan.io Announces Promotions and Expansion
February 5, 2021
2020 was a year of tremendous growth for lifespan.io. As many of you have likely noticed, our news outlet team has hired two more excellent science journalists, Arkadi Mazin and
ChromaDex $25 Million Sale of Common Stock
February 24, 2021
ChromaDex has recently announced that it has agreed a securities purchase agreement for the sale of $25 million of its common stock in a private placement. The private placement was led by an international investor, with ChromaDex agreeing to sell 3,846,153 shares of its common stock
Longevity Pharmacology has Come of Age
February 24, 2021
A bold feature article published in Drug Discovery Today illustrates the coming of age of longevity pharmacology. Dr. João Pedro de Magalhães, one of the biggest names in longevity research, outlined some of the great strides taken in the last two decades, as various discoveries have
SIRT3 Replenishment Reverses Lung Fibrosis in Mice
February 23, 2021
Scientists have successfully reversed persistent lung fibrosis in mice by overexpressing the SIRT3 protein in lung macrophages [1]. Fibrosis: not knowing when to stop Fibrosis may be the true apex predator of humanity. According to one study, fibrotic diseases that cause organ failure are responsible for
Humacyte in Deal to Develop Prosthetic Vasculature
February 22, 2021
Tissue engineering company Humacyte is about to make a special purpose acquisition company (SPAC) deal in order to go public. The company is developing bioengineered Human Acellular Vessels (HAVs), which provide prosthetic vasculature to support the repair, reconstruction, and replacement of blood vessels damaged by injury
Atrophy of the Neuronal Circadian Clock Is a Disease of Aging
February 19, 2021
Today, researcher Victor Bjoerk talks us through his latest published paper, in which he describes a neurodegenerative disease that affects the circadian clock. A circadian clock disease With aging, the brain runs into multiple issues; however, some are more serious than others and cause disease symptoms
The NIA Is Funding Clinical Trials Against Aging
February 18, 2021
The National Institutes of Aging in the United States, a component of the National Institutes of Health, is funding clinical trials for interventions that directly affect the root causes of age-related diseases. Direct funding for trials against aging Probably the most important and interesting part of
Replacing Aging With Jean Hébert
February 17, 2021
Replacing Aging by Jean Hébert is the latest longevity book published for public consumption. While books such as these seem to be coming out more regularly, readers who have already tackled David Sinclair’s Lifespan, Nir Barzilai’s Age Later, or Aubrey De Grey’s Ending Aging shouldn’t simply
Lessons from Longevity Therapeutics 2021 – Part 4
February 16, 2021
This is the final installment in our coverage of Longevity Therapeutics 2021, a conference that brought together some of the biggest names in longevity research. Read the previous parts here, here, and here. Dr. Andrei Gudkov – Chief Scientific Officer, Genome Protection Andrei Gudkov gave a
Developing Our Ethics Code of Longevity Journalism
February 16, 2021
When lifespan.io was started in 2014 as a crowdfunding platform, we didn’t really know that we would become a news outlet covering longevity research. We didn’t plan to be one. However, after running our first crowdfunding campaign, we realized that public awareness of aging research is
Proposing Gerobiotics as a New Gut Microbiome Research Field
February 15, 2021
The aging of the microbiome, the collective bacteria, fungi, protozoa and viruses that live on and inside our bodies, has become a popular research topic in recent years. The microbiome appears to influence aging There has been increasing interest in the influence of this microbial community,
The Intertwined Nature of NAD+, CD38, and Senescence
February 12, 2021
Aging is a multifactorial and complex process; indeed, it is probably the most complex disorder known. It is made up of a combination of dozens of malfunctions locked together in an accelerating spiral of decline. Despite this undeniable complexity, which is captured to some extent by
Male and Female Gut Microbiomes Converge With Age
February 11, 2021
While the gut microbiomes of young men and women are distinct, that difference disappears in older people, according to a new study. These findings add to the growing pool of data that links the gut microbiome and aging, although the nature of the links and the
Senescent Cells in the Aging Retina
February 8, 2021
A review published in the Journal of Neuroinflammation explores the potential application of senotherapies, particularly in the context of treating age-related macular degeneration [1]. Introducing cellular senescence One of the most advanced approaches to treating aging and age-related diseases is that of addressing the presence of
Increasing NAD+ Reduces Amyloids and Benefits Mitochondria
February 5, 2021
Aging is accompanied by the loss of proteostasis, the accumulation of misfolded proteins and their amyloid aggregates, and mitochondrial dysfunction, which is partially characterized by the loss of mitochondrial homeostasis, the delicate balance that mitochondria need in order to produce energy without polluting the body with
lifespan.io Announces Promotions and Expansion
February 5, 2021
2020 was a year of tremendous growth for lifespan.io. As many of you have likely noticed, our news outlet team has hired two more excellent science journalists, Arkadi Mazin and Greg Gillipsie. Nicola Bagala, who produces LifeXtenShow, was assigned in the summer of 2020 to supervise