Category: Biology of Aging
Two Proteins Allow LDL Cholesterol into Our Cells
July 2, 2020
Researchers have found out how LDL cholesterol is able to enter our cells with the help of two proteins that form a doorway into the cell. The findings have ramifications
Pilot Study Results Suggest Epigenetic Age Reversal
June 30, 2020
Today, we want to highlight a press release from Ponce de Leon Health that talks about the results of a pilot consumer trial that the company has recently concluded. The
New Evidence of Common Genetic Causes in Age-Related Diseases
June 30, 2020
By using a large UK health databank and advanced methods of statistical analysis, scientists have discovered genetic ties between various age-related diseases and proposed several candidate drugs for upstream intervention.
Nanoparticles Deliver Twin Drug Payload for Atherosclerosis
June 26, 2020
Cyclodextrins have been of particular interest in the context of treating atherosclerosis, so today we want to highlight some interesting research that uses a novel delivery method to combat this
Reversing Atherosclerosis by Resetting Gut Bacteria
June 25, 2020
A new study has seen researchers alter the balance of harmful bacteria in the gut microbiome to reduce cholesterol and reverse atherosclerosis in mice fed a high-fat Western diet. What
A Strong Link Between Alzheimer’s and Senescence
June 24, 2020
In a recent study, researchers from the Buck Institute have shown that cellular senescence, one of the hallmarks of aging, is partially responsible for Alzheimer’s disease. Cellular senescence is unusual
Role of the Immune System in Removing Senescent Cells
June 23, 2020
Could the immune system itself be the best way to purge senescent cells, which accumulate as we age, from the body? A new review takes a look at the role
Deploying Immunotherapy Against Senescent Cells
June 22, 2020
Researchers are starting to test the use of immunotherapies, normally used for treating cancer, to target senescent cells, which accumulate in our bodies as we age and are implicated in
The Gene LMNA’s Effect on Aging
June 19, 2020
LMNA, a gene coding for lamins, whose mutations cause many developmental diseases, is linked to Hutchinson-Gilford Progeria (HGP) [1]. HGP is a disease that causes premature aging and is currently
Gut Bacteria Can Predict Your Biological Age
June 19, 2020
Can we use the bacteria in our gut to measure how biologically old we are? Some researchers certainly think we can and have developed a microbiome clock that examines the
Can Aging Research Prevent the Next Pandemic?
June 18, 2020
The world is reeling from the SARS-CoV-2 (COVID-19) pandemic, which has both had severe economic and humanitarian effects. As we continue to practice social distancing, we should ask ourselves: How
Hair Graying May Be Reversible
June 17, 2020
A team of researchers have discovered a novel way to study the process of hair graying, finding it potentially reversible and linked to psychological stress. The abundant anecdotal evidence of
Removing Some Senescent Cells May Have Consequences
June 15, 2020
Senescent cell accumulation is a likely reason we age, but removing some populations of specialized cells that have turned senescent may have negative consequences, according to a new study. What
NAD+ Restores Mitochondrial Function in Egg Cells
June 11, 2020
Researchers have discovered that a lack of NAD+ is responsible for mitochondrial dysfunction in egg cells (oocytes), leading to decreased fertility with age. Mitochondria in oocytes Given how much it
Niacin May Prove Useful Against Brain Cancer
June 10, 2020
A possible new role for niacin has been discovered in the fight against brain cancer. An old vitamin Niacin is a form of vitamin B3 and has been a popular
Two Proteins Allow LDL Cholesterol into Our Cells
July 2, 2020
Researchers have found out how LDL cholesterol is able to enter our cells with the help of two proteins that form a doorway into the cell. The findings have ramifications for treating heart disease, which is currently the world’s greatest killer. Revealing how LDL gets into
Pilot Study Results Suggest Epigenetic Age Reversal
June 30, 2020
Today, we want to highlight a press release from Ponce de Leon Health that talks about the results of a pilot consumer trial that the company has recently concluded. The company claims that it has been successful in reducing the epigenetic age of participants by an
New Evidence of Common Genetic Causes in Age-Related Diseases
June 30, 2020
By using a large UK health databank and advanced methods of statistical analysis, scientists have discovered genetic ties between various age-related diseases and proposed several candidate drugs for upstream intervention. Building age-of-onset profiles of diseases The very fact that multitudes of age-related diseases (ARDs) exist alludes
Nanoparticles Deliver Twin Drug Payload for Atherosclerosis
June 26, 2020
Cyclodextrins have been of particular interest in the context of treating atherosclerosis, so today we want to highlight some interesting research that uses a novel delivery method to combat this disease. Nanoparticles improve drug delivery Cyclodextrins describe a group of cyclic oligosaccharides, which have a varied
Reversing Atherosclerosis by Resetting Gut Bacteria
June 25, 2020
A new study has seen researchers alter the balance of harmful bacteria in the gut microbiome to reduce cholesterol and reverse atherosclerosis in mice fed a high-fat Western diet. What is the gut microbiome? The gut microbiome describes the varied community of bacteria, archaea, eukarya, and
A Strong Link Between Alzheimer’s and Senescence
June 24, 2020
In a recent study, researchers from the Buck Institute have shown that cellular senescence, one of the hallmarks of aging, is partially responsible for Alzheimer’s disease. Cellular senescence is unusual in the brain. As the researchers explain, the normal method for determining whether or not a
Role of the Immune System in Removing Senescent Cells
June 23, 2020
Could the immune system itself be the best way to purge senescent cells, which accumulate as we age, from the body? A new review takes a look at the role of the immune system in removing these problematic cells. What are senescent cells? As you age,
Deploying Immunotherapy Against Senescent Cells
June 22, 2020
Researchers are starting to test the use of immunotherapies, normally used for treating cancer, to target senescent cells, which accumulate in our bodies as we age and are implicated in many age-related conditions. What are senescent cells? As you age, increasing numbers of your cells enter
The Gene LMNA’s Effect on Aging
June 19, 2020
LMNA, a gene coding for lamins, whose mutations cause many developmental diseases, is linked to Hutchinson-Gilford Progeria (HGP) [1]. HGP is a disease that causes premature aging and is currently affecting around 390 children. Their average life expectancy is around 13 years, but some affected individuals
Gut Bacteria Can Predict Your Biological Age
June 19, 2020
Can we use the bacteria in our gut to measure how biologically old we are? Some researchers certainly think we can and have developed a microbiome clock that examines the bacteria living in our guts to predict our age. The microbiome The gut microbiome is a
Can Aging Research Prevent the Next Pandemic?
June 18, 2020
The world is reeling from the SARS-CoV-2 (COVID-19) pandemic, which has both had severe economic and humanitarian effects. As we continue to practice social distancing, we should ask ourselves: How can we avoid similar pandemics in the future? Aging and infectious disease are linked As we
Hair Graying May Be Reversible
June 17, 2020
A team of researchers have discovered a novel way to study the process of hair graying, finding it potentially reversible and linked to psychological stress. The abundant anecdotal evidence of hair graying overnight (or, as Shakespeare put it in Henry IV: “Thy father’s beard is turned
Removing Some Senescent Cells May Have Consequences
June 15, 2020
Senescent cell accumulation is a likely reason we age, but removing some populations of specialized cells that have turned senescent may have negative consequences, according to a new study. What are senescent cells? As you get older, more and more of your cells enter into a
NAD+ Restores Mitochondrial Function in Egg Cells
June 11, 2020
Researchers have discovered that a lack of NAD+ is responsible for mitochondrial dysfunction in egg cells (oocytes), leading to decreased fertility with age. Mitochondria in oocytes Given how much it must divide to create a human being, the oocyte is the largest cell in the human
Niacin May Prove Useful Against Brain Cancer
June 10, 2020
A possible new role for niacin has been discovered in the fight against brain cancer. An old vitamin Niacin is a form of vitamin B3 and has been a popular supplement since its discovery in 1937 by the researcher Conrad Elvehjem. Niacin is actually nicotinic acid,