Category: Artificial Intelligence
Senolytics Restore Regeneration in Killifish
July 13, 2023
Researchers publishing in npj regenerative medicine have found that destroying senescent cells through a well-known senolytic combination gives older killifish back some of their regenerative abilities. Regeneration, for a while
Editing Mitochondrial DNA
July 12, 2023
The Journal Club returns on 25th July at 12:00 Eastern time to the lifespan.io Facebook channel. Editing mitochondrial DNA (mtDNA) has long been a challenge and systems such as CRISPR,
Using Proteins and RNA to Determine How Old You Are
July 10, 2023
A paper published in Aging goes into detail about the proteins and RNA pieces that increase and decrease with aging, suggesting a multiple-clock approach to biomarkers. Blood proteins change with
The Longevity Factor Klotho Improves Memory in Monkeys
July 9, 2023
Researchers have explained in Nature Aging how klotho, a factor associated with longevity, improves the cognitive abilities of rhesus macaques. Moving on from mice This paper begins with a discussion
Cellular Senescence Drives Regeneration in Cnidarians
July 7, 2023
Scientists have demonstrated that full-body regeneration in cnidarians, a group of animals that includes the jellyfish and hydra, can be driven by signals from senescent cells [1]. This might be
Microbial Composition May Affect Lifespan
July 5, 2023
New research published in Scientific Reports suggests that microbes in the human gut and mouth can impact how long people live [1]. Bacteria and other microbes are often associated with
Stem Cell Signals Encourage Blood Vessel Formation in Mice
July 3, 2023
Researchers publishing in Aging have outlined how biochemical signals derived from created stem cells encourage blood vessels to form new branches in naturally aged mice. iPSCs, exosomes, and angiogenesis Exposure
Vitalik Buterin Exclusive Interview: Longevity, AI and More
May 30, 2023
Vitalik Buterin holding Zuzu, the puppy rescued by people of Zuzalu. Photo: Michelle Lai Don’t try finding Zuzalu on a map; it doesn’t exist anymore. It was a “pop-up city”
Using AI to Discover New Rapamycin-Like Molecules
May 24, 2023
In a recent paper published in International Journal of Medical Sciences, researchers have described how they used artificial intelligence and machine learning tools to find mTOR-inhibiting molecules [1]. mTOR is
Using Machine Learning to Find Senolytics
May 4, 2023
Research published today in Nature Aging has described a machine learning algorithm that finds senescent cell-removing drugs (senolytics) and compared the algorithm’s discoveries to existing compounds. A quest for effective
AI Better Than Humans At Healthcare Questions
May 3, 2023
Scientists have compared doctor-written and chatbot-generated responses to healthcare-related questions, and the results don’t look good for Team Human [1]. Ask your doctor? Access to healthcare has been linked to
What AI Technology Is Doing for Longevity Now
April 26, 2023
In March 2023, MIT Technology Review revealed that Sam Altman, the CEO of OpenAI (ChatGPT), was the mystery investor behind the $180 million investment into stealth startup Retro Biosciences, a
Using Artificial Intelligence to Rapidly Identify Brain Tumors
October 6, 2017
The use of artificial intelligence and, in particular, machine learning is becoming increasingly popular in research. These systems excel at high-speed data analysis, interpretation, and laborious research tasks, such as
Senolytics Restore Regeneration in Killifish
July 13, 2023
Researchers publishing in npj regenerative medicine have found that destroying senescent cells through a well-known senolytic combination gives older killifish back some of their regenerative abilities. Regeneration, for a while Killifish, like starfish and salamanders, are some of the most well-known regenerators of the animal kingdom,
Editing Mitochondrial DNA
July 12, 2023
The Journal Club returns on 25th July at 12:00 Eastern time to the lifespan.io Facebook channel. Editing mitochondrial DNA (mtDNA) has long been a challenge and systems such as CRISPR, which make editing regular DNA faster and easier, are very difficult to use when it comes
Using Proteins and RNA to Determine How Old You Are
July 10, 2023
A paper published in Aging goes into detail about the proteins and RNA pieces that increase and decrease with aging, suggesting a multiple-clock approach to biomarkers. Blood proteins change with age The researchers start out by discussing existing clocks based on such measurements as imaging [1]
The Longevity Factor Klotho Improves Memory in Monkeys
July 9, 2023
Researchers have explained in Nature Aging how klotho, a factor associated with longevity, improves the cognitive abilities of rhesus macaques. Moving on from mice This paper begins with a discussion of klotho and how it relates to aging. In mice, klotho has been found to improve
Cellular Senescence Drives Regeneration in Cnidarians
July 7, 2023
Scientists have demonstrated that full-body regeneration in cnidarians, a group of animals that includes the jellyfish and hydra, can be driven by signals from senescent cells [1]. This might be the original purpose of cellular senescence. Why can’t we regrow our arms? There are many examples
Microbial Composition May Affect Lifespan
July 5, 2023
New research published in Scientific Reports suggests that microbes in the human gut and mouth can impact how long people live [1]. Bacteria and other microbes are often associated with diseases, but disease-causing microbes are only a minority. The majority of microbes are harmless or beneficial
Stem Cell Signals Encourage Blood Vessel Formation in Mice
July 3, 2023
Researchers publishing in Aging have outlined how biochemical signals derived from created stem cells encourage blood vessels to form new branches in naturally aged mice. iPSCs, exosomes, and angiogenesis Exposure to the Yamanaka factors can cause ordinary cells to teturn to early stemness, from which they
Vitalik Buterin Exclusive Interview: Longevity, AI and More
May 30, 2023
Vitalik Buterin holding Zuzu, the puppy rescued by people of Zuzalu. Photo: Michelle Lai Don’t try finding Zuzalu on a map; it doesn’t exist anymore. It was a “pop-up city” conceived by the tech entrepreneur Vitalik Buterin, creator of Ethereum, and a group of like-minded people
Using AI to Discover New Rapamycin-Like Molecules
May 24, 2023
In a recent paper published in International Journal of Medical Sciences, researchers have described how they used artificial intelligence and machine learning tools to find mTOR-inhibiting molecules [1]. mTOR is a common target for lifespan extension interventions The mechanistic target of rapamycin (mTOR) is a well-known
Using Machine Learning to Find Senolytics
May 4, 2023
Research published today in Nature Aging has described a machine learning algorithm that finds senescent cell-removing drugs (senolytics) and compared the algorithm’s discoveries to existing compounds. A quest for effective therapeutics After covering familiar territory regarding senescent cells, this paper begins with a discussion of existing
AI Better Than Humans At Healthcare Questions
May 3, 2023
Scientists have compared doctor-written and chatbot-generated responses to healthcare-related questions, and the results don’t look good for Team Human [1]. Ask your doctor? Access to healthcare has been linked to longer lifespan, and good healthcare often starts with a good initial consultation. A group of researchers,
What AI Technology Is Doing for Longevity Now
April 26, 2023
In March 2023, MIT Technology Review revealed that Sam Altman, the CEO of OpenAI (ChatGPT), was the mystery investor behind the $180 million investment into stealth startup Retro Biosciences, a biotech company with the ambition of “adding 10 years to the human lifespan.” This investment marks
Using Artificial Intelligence to Rapidly Identify Brain Tumors
October 6, 2017
The use of artificial intelligence and, in particular, machine learning is becoming increasingly popular in research. These systems excel at high-speed data analysis, interpretation, and laborious research tasks, such as image assessment. One of the areas in which machine learning has been enjoying success is image