Category: Research
Stem Cell Signals Encourage Blood Vessel Formation in Mice
July 3, 2023
Researchers publishing in Aging have outlined how biochemical signals derived from created stem cells encourage blood vessels to form new branches in naturally aged mice. iPSCs, exosomes, and angiogenesis Exposure
A Potential Next Generation For Epigenetic Clocks
June 29, 2023
A study recently published in Aging Cell has discovered an entirely new method of looking at methylation and experimented with multiple ways of analyzing it. Not just a clock While
The Links Between Herpes and Dementia
June 29, 2023
One of the most common diseases in the world is herpes, as 50 to 80% of Americans have this illness. The herpes simplex virus, which causes cold sores, is
Activating A Single Gene Rejuvenates Mice
June 28, 2023
In a new study published in Aging Cell [1], researchers report that transient activation of the Yamanaka factor Oct4 allowed partial reprogramming of cells, which led to rejuvenation in these
Preserved Kidneys Rewarmed and Transplanted in Rats
June 27, 2023
For the first time in history, scientists have been able to freeze, preserve, rewarm, and transplant rat kidneys with a new method of organ cryopreservation [1]. The rewarming problem
Journal Club June 2023
June 24, 2023
For the Journal Club this month, at 12:00 Eastern time on Tuesday, June 27, we are taking a look at the recent paper that explores the reason why the bowhead
Scientists Modify Lettuce to Make Orally Available Insulin
June 23, 2023
Researchers have genetically engineered lettuce to produce human insulin. The resulting plant-based drug, which can be taken orally, was successfully tested in mice [1]. An epidemic and a costly
Dr. Matthew Walker Tells Us Why We Sleep
June 20, 2023
“Why We Sleep: Unlocking the Power of Sleep and Dreams” by Matthew Walker, renowned sleep research scientist and psychiatry professor at Harvard, is a comprehensive exploration of sleep that offers
Bacteria May Be Fueling Cancer with Methionine
June 20, 2023
Scientists have found that the tumor microenvironment in lung adenocarcinoma favors methionine-producing bacteria, which, in turn, help the cancer survive nutrient scarcity [1]. Micro-friends or micro-foes? Our bodies host a
Clinical Trial: Collagen Peptides Reduce AGEs in Skin
June 19, 2023
A placebo-controlled, double-blinded human clinical trial published in Bioscience, Biotechnology, and Biochemistry has determined that collagen peptide ingestion reduces the amount of advanced glycation end-products (AGEs) in the skin. When
Shingles Vaccine May Protect Against Alzheimer’s
June 16, 2023
New research suggests that vaccination against shingles, a disease caused by the varicella zoster virus, can provide some protection against Alzheimer’s disease, mostly in women [1]. Viruses and aging With
How Cancer Hijacks the Nervous System
June 15, 2023
A review article published in Nature has outlined the current research into how the nervous system’s signals affect cancer growth. A surprising connection This review opens with a bold but
Rapamycin Users Report Positive Effects in Survey
June 14, 2023
A new study published in GeroScience addresses the efficacy and side effects of off-label rapamycin as a preventive therapy to maintain healthspan [1]. From a small island to a reportedly
Sirtuins May Help Against Inflammatory Spinal Degeneration
June 12, 2023
Researchers publishing in Aging have outlined a relationship between disc degeneration, macrophage polarization, inflammation, and sirtuins, demonstrating their effectiveness in a rat model of the disease. A crippling and painful
How Superior DNA Repair Gives Bowhead Whales Longevity
June 9, 2023
Scientists have found a possible explanation for bowhead whales’ exceptional lifespan, and it might be translatable to humans [1]. More cells, less cancer With some exceptions, body size is strongly
Stem Cell Signals Encourage Blood Vessel Formation in Mice
July 3, 2023
Researchers publishing in Aging have outlined how biochemical signals derived from created stem cells encourage blood vessels to form new branches in naturally aged mice. iPSCs, exosomes, and angiogenesis Exposure to the Yamanaka factors can cause ordinary cells to teturn to early stemness, from which they
A Potential Next Generation For Epigenetic Clocks
June 29, 2023
A study recently published in Aging Cell has discovered an entirely new method of looking at methylation and experimented with multiple ways of analyzing it. Not just a clock While we have reported extensively on the use of epigenetic methylation clocks, the genes that become activated
The Links Between Herpes and Dementia
June 29, 2023
One of the most common diseases in the world is herpes, as 50 to 80% of Americans have this illness. The herpes simplex virus, which causes cold sores, is normally transmitted through person-to-person contact. This illness leaves the patient with blisters clustered around the mouth.
Activating A Single Gene Rejuvenates Mice
June 28, 2023
In a new study published in Aging Cell [1], researchers report that transient activation of the Yamanaka factor Oct4 allowed partial reprogramming of cells, which led to rejuvenation in these cells and in a mouse model of premature aging. This research used a mouse model of
Preserved Kidneys Rewarmed and Transplanted in Rats
June 27, 2023
For the first time in history, scientists have been able to freeze, preserve, rewarm, and transplant rat kidneys with a new method of organ cryopreservation [1]. The rewarming problem Today, organ transplantation is severely limited by the fact that organs can only be preserved for
Journal Club June 2023
June 24, 2023
For the Journal Club this month, at 12:00 Eastern time on Tuesday, June 27, we are taking a look at the recent paper that explores the reason why the bowhead whale is so long lived. If you want to get up to speed, check out the
Scientists Modify Lettuce to Make Orally Available Insulin
June 23, 2023
Researchers have genetically engineered lettuce to produce human insulin. The resulting plant-based drug, which can be taken orally, was successfully tested in mice [1]. An epidemic and a costly drug Diabetes mellitus has reached epidemic proportions, affecting about half a billion people worldwide. This debilitating
Dr. Matthew Walker Tells Us Why We Sleep
June 20, 2023
“Why We Sleep: Unlocking the Power of Sleep and Dreams” by Matthew Walker, renowned sleep research scientist and psychiatry professor at Harvard, is a comprehensive exploration of sleep that offers a rich blend of science, research, and practical advice. The book is divided into four parts,
Bacteria May Be Fueling Cancer with Methionine
June 20, 2023
Scientists have found that the tumor microenvironment in lung adenocarcinoma favors methionine-producing bacteria, which, in turn, help the cancer survive nutrient scarcity [1]. Micro-friends or micro-foes? Our bodies host a mind-bending number of microorganisms, but most effects of this cohabitation are not well understood. Scientists have
Clinical Trial: Collagen Peptides Reduce AGEs in Skin
June 19, 2023
A placebo-controlled, double-blinded human clinical trial published in Bioscience, Biotechnology, and Biochemistry has determined that collagen peptide ingestion reduces the amount of advanced glycation end-products (AGEs) in the skin. When the Maillard reaction is a problem AGEs have been known to be harmful for decades [1],
Shingles Vaccine May Protect Against Alzheimer’s
June 16, 2023
New research suggests that vaccination against shingles, a disease caused by the varicella zoster virus, can provide some protection against Alzheimer’s disease, mostly in women [1]. Viruses and aging With causes of many age-related diseases remaining unclear, in recent years, scientists have been looking into the
How Cancer Hijacks the Nervous System
June 15, 2023
A review article published in Nature has outlined the current research into how the nervous system’s signals affect cancer growth. A surprising connection This review opens with a bold but heavily documented claim: the central nervous system (CNS) affects various cancers through signaling mechanisms, even those
Rapamycin Users Report Positive Effects in Survey
June 14, 2023
A new study published in GeroScience addresses the efficacy and side effects of off-label rapamycin as a preventive therapy to maintain healthspan [1]. From a small island to a reportedly life-extending drug When it was discovered in 1972 on the island of Rapa Nui, rapamycin was
Sirtuins May Help Against Inflammatory Spinal Degeneration
June 12, 2023
Researchers publishing in Aging have outlined a relationship between disc degeneration, macrophage polarization, inflammation, and sirtuins, demonstrating their effectiveness in a rat model of the disease. A crippling and painful disease Intervertebral disc degeneration (IDD) is a major cause of pain and disability [1], as it
How Superior DNA Repair Gives Bowhead Whales Longevity
June 9, 2023
Scientists have found a possible explanation for bowhead whales’ exceptional lifespan, and it might be translatable to humans [1]. More cells, less cancer With some exceptions, body size is strongly correlated with longevity across species. While this can be explained evolutionarily (larger species have fewer extrinsic