Category: Research
Fatty Tissue Generated on a Chip
October 14, 2020
Recent research published in the scientific journal Lab on a Chip sheds light on the behavior of adipocytes, the primary cells of our fat tissue.
T Cell Progenitors Boost Stem Cell Therapy Effectiveness
October 13, 2020
In a review paper, a group of scientists highlight a new strategy that addresses the shortcomings of stem cell therapy by adding T cell progenitors to the graft [1]. HSCT
A New Senolytic Enters Human Trials
October 13, 2020
Unity Biotechnology has recently announced the launch of its Phase 1 study of UBX1325 for patients with diabetic macular edema. The drug is designed to remove problematic senescent cells from
Regenerating Skin With a Single Protein
October 12, 2020
Researchers have identified a factor present in the skin of baby mice that controls the formation of hair follicles during their early development. The factor is turned off in adult
Creating Anti-Glucosepane Antibodies
October 9, 2020
New research takes us a step close to finding ways to remove the advanced glycation end-product known as glucosepane, a likely reason why our arteries stiffen as we age. A
Senescent Cells Have Less SIRT1 as a Result of Autophagy
October 8, 2020
Genes in the sirtuin family are conserved across a wide range of species and are involved in cellular metabolism, immune response, and aging. SIRT1 is known to decline during aging,
A New Atlas of Dental Cells
October 7, 2020
A recent study published in Nature Communications has outlined an atlas for the various differentiated and stem cell populations found in our teeth.
Medin Aggregates Cause Cerebrovascular Dysfunction in Mice
October 2, 2020
A new study conducted by researchers from Germany and the UK has shown that accumulation of medin, an amyloid of the protein MFG-E8, leads to cerebrovascular (brain blood vessel) disease
Spheroids Promote Vascularization in Tissue Regeneration
September 30, 2020
New results published in the journal Biofabrication may help researchers on their quest to regenerate vascularized tissues.
Nanoparticles with Self-Replicating RNA Stop Cancer in Mice
September 29, 2020
A group of researchers have devised an effective anti-cancer therapy by loading cytokine-coding RNA fragments into lipid nanoparticles and injecting them directly into the tumor [1]. Anti-cancer immunotherapy is a
Plant Flavonoid Naringenin Is a Senotherapeutic
September 28, 2020
Researchers have published a new animal study showing that the plant flavonoid naringenin may be useful in targeting problematic senescent cells in the brain. Ribes meyeri (also known as Ribes
Mitochondrial Mutations Associated with Fertility Decline
September 24, 2020
According to new research, mutations accumulate in the mitochondrial DNA of egg cells, leading to changes in cellular metabolism, which result in reduced fertility. The study also showed that Nicotinamide
A New Microporous Membrane for Skin Regeneration
September 23, 2020
A new study published in Archives of Dermatological Research has shown that a novel microporous membrane can promote the regeneration of healthy human skin. Skin regeneration Skin regeneration has been
Microtubule Stabilization Ameliorates Alzheimer’s Symptoms
September 22, 2020
A group of researchers has been able to ameliorate Alzheimer-like pathologies in mice by using a microtubule-stabilizing compound [1]. Cellular highways Microtubules (MTs) are tiny pipe-like structures that are made
A Link Between the Microbiome, Heat, and Osteoporosis
September 21, 2020
Researchers from the University of Geneva have shown that a warm environment improves bone strength and highlights a related link with gut microbiome composition. These findings also pave the way
Fatty Tissue Generated on a Chip
October 14, 2020
Recent research published in the scientific journal Lab on a Chip sheds light on the behavior of adipocytes, the primary cells of our fat tissue.
T Cell Progenitors Boost Stem Cell Therapy Effectiveness
October 13, 2020
In a review paper, a group of scientists highlight a new strategy that addresses the shortcomings of stem cell therapy by adding T cell progenitors to the graft [1]. HSCT has a problem Today, one of the few ways to alleviate immune system damage from chemotherapy
A New Senolytic Enters Human Trials
October 13, 2020
Unity Biotechnology has recently announced the launch of its Phase 1 study of UBX1325 for patients with diabetic macular edema. The drug is designed to remove problematic senescent cells from the body which accumulate as we get older and are a reason we age. UBX1325 is
Regenerating Skin With a Single Protein
October 12, 2020
Researchers have identified a factor present in the skin of baby mice that controls the formation of hair follicles during their early development. The factor is turned off in adult mice, but when it is turned back on, it allows them to regenerate their skin following
Creating Anti-Glucosepane Antibodies
October 9, 2020
New research takes us a step close to finding ways to remove the advanced glycation end-product known as glucosepane, a likely reason why our arteries stiffen as we age. A possible solution to the problem Some years ago, Aubrey de Grey from the SENS Research Foundation
Senescent Cells Have Less SIRT1 as a Result of Autophagy
October 8, 2020
Genes in the sirtuin family are conserved across a wide range of species and are involved in cellular metabolism, immune response, and aging. SIRT1 is known to decline during aging, but the mechanisms involved in this process were not known. Now, an international team has clarified
A New Atlas of Dental Cells
October 7, 2020
A recent study published in Nature Communications has outlined an atlas for the various differentiated and stem cell populations found in our teeth.
Medin Aggregates Cause Cerebrovascular Dysfunction in Mice
October 2, 2020
A new study conducted by researchers from Germany and the UK has shown that accumulation of medin, an amyloid of the protein MFG-E8, leads to cerebrovascular (brain blood vessel) disease in wild-type mice [1]. More than just amyloid beta While amyloidosis is most associated with brain
Spheroids Promote Vascularization in Tissue Regeneration
September 30, 2020
New results published in the journal Biofabrication may help researchers on their quest to regenerate vascularized tissues.
Nanoparticles with Self-Replicating RNA Stop Cancer in Mice
September 29, 2020
A group of researchers have devised an effective anti-cancer therapy by loading cytokine-coding RNA fragments into lipid nanoparticles and injecting them directly into the tumor [1]. Anti-cancer immunotherapy is a powerful novel strategy that has given hope to millions of cancer patients. The immune system has
Plant Flavonoid Naringenin Is a Senotherapeutic
September 28, 2020
Researchers have published a new animal study showing that the plant flavonoid naringenin may be useful in targeting problematic senescent cells in the brain. Ribes meyeri (also known as Ribes meyeri maxim) is a native plant to central Asia, Mongolia and Northeast Afghanistan and is part
Mitochondrial Mutations Associated with Fertility Decline
September 24, 2020
According to new research, mutations accumulate in the mitochondrial DNA of egg cells, leading to changes in cellular metabolism, which result in reduced fertility. The study also showed that Nicotinamide mononucleotide (NMN) treatment can restore the metabolic balance in aging mouse oocytes, rescuing fertility. Defective eggs
A New Microporous Membrane for Skin Regeneration
September 23, 2020
A new study published in Archives of Dermatological Research has shown that a novel microporous membrane can promote the regeneration of healthy human skin. Skin regeneration Skin regeneration has been a major goal for tissue engineering and regenerative medicine. However, natural skin is difficult to recapitulate
Microtubule Stabilization Ameliorates Alzheimer’s Symptoms
September 22, 2020
A group of researchers has been able to ameliorate Alzheimer-like pathologies in mice by using a microtubule-stabilizing compound [1]. Cellular highways Microtubules (MTs) are tiny pipe-like structures that are made mostly of the polymerized protein tubulin. They constitute an important part of the cytoskeleton, a network
A Link Between the Microbiome, Heat, and Osteoporosis
September 21, 2020
Researchers from the University of Geneva have shown that a warm environment improves bone strength and highlights a related link with gut microbiome composition. These findings also pave the way for novel therapies for the treatment of osteoporosis. Turning up the heat Osteoporosis is an age-related