Category: Supplements
NMN Human Trial Results Published
June 2, 2022
The data from a multicenter NMN clinical trial have been published with some very modest but still interesting results [1]. What is NMN? NMN is short for nicotinamide mononucleotide, a
Vitamin D Dosing Safety in a Randomized, Controlled Trial
March 9, 2022
New data has been released from the Vitamin D Type 2 Diabetes (D2d) study [1]. This study is a randomized, controlled trial that includes overweight and obese people studied at
Urolithin A Affects Muscle and Mitochondria in Older Adults
February 23, 2022
A study published in the Journal of the American Medical Association has examined the dosage and safety of a urolithin A supplement [1]. This study also examined urolithin A‘s effect
Puerarin Shows Promise in Fighting COPD in Cells
February 14, 2022
Publishing in Aging, a team of researchers has discovered how puerarin, an extract of kudzu, ameliorates chronic obstructive pulmonary disorder (COPD) signs in cellular cultures by limiting mitophagy: the consumption
Supplement Combo Boosts Working Memory in Older People
January 5, 2022
An open-access human study published in Clinical Nutrition has found that a combination of supplements is beneficial for working memory. Identifying the dietary compounds Specific types of eating patterns have
What Is Quercetin? A Summary of Quercetin
December 20, 2021
Found in many fruits and vegetables, quercetin may have some potential in the context of aging. Here, we take a look at this natural antioxidant and popular dietary supplement. What
What is Metformin? A Summary of N,N-dimethylbiguanide
November 17, 2021
We take a look at this diabetic drug that some researchers think may slow down aging. What is metformin? Metformin is a prescription drug and is available as a tablet
What is Rapamycin? A Summary of Rapamycin
October 8, 2021
We take a look at rapamycin and why some researchers think it could be useful in combating aging. What is rapamycin? Rapamycin is a macrolide, a class of antibiotic that
What is Nicotinamide Riboside? A Summary of NR
September 27, 2021
Nicotinamide riboside (NR) is part of the B3 vitamin family. Like other forms of vitamin B3, nicotinamide riboside gets converted into nicotinamide adenine dinucleotide (NAD+), a coenzyme essential for life.
What is Resveratrol? A Summary of Resveratrol
August 26, 2021
Probably best known for its presence in grapes and wine, this popular dietary supplement may have a few tricks up its sleeve. What is resveratrol? Resveratrol is a stilbenoid, a
What is Spermidine? A Summary of Spermidine
August 6, 2021
Found in grapefruit, spermidine is one of the more interesting polyamines. Some research suggests that spermidine may slow down aging and promote healthy longevity. What is spermidine? Spermidine is a
What is Berberine? A Summary of Berberine Alkaloid
August 5, 2021
We take a look at berberine, a popular supplement in the life extension community that is often touted as being similar to metformin. What is berberine? Berberine is an ammonium
What is Magnesium? A Summary of Magnesium
July 31, 2021
Magnesium is a common element and is found in a variety of foods, but not everyone gets enough of this essential element, which is vital for cellular processes. What is
What is Alpha-lipoic Acid? A Summary of ALA
July 24, 2021
Alpha-lipoic acid (also known as ALA) is a common supplement, and we take a look at it in the context of aging. What is alpha-lipoic acid? Alpha-lipoic acid is an
What is Arginine? A Summary of L-Arginine
July 23, 2021
Arginine is a popular sports supplement, but could it also be useful in the context of healthy longevity? What is arginine? Arginine, also known as L-arginine, is an amino acid,
NMN Human Trial Results Published
June 2, 2022
The data from a multicenter NMN clinical trial have been published with some very modest but still interesting results [1]. What is NMN? NMN is short for nicotinamide mononucleotide, a naturally occurring molecule present in all species. It is a precursor of nicotinamide adenine dinucleotide (NAD+),
Vitamin D Dosing Safety in a Randomized, Controlled Trial
March 9, 2022
New data has been released from the Vitamin D Type 2 Diabetes (D2d) study [1]. This study is a randomized, controlled trial that includes overweight and obese people studied at 22 academic medical centers in the United States. This data was collected between October 2013 and
Urolithin A Affects Muscle and Mitochondria in Older Adults
February 23, 2022
A study published in the Journal of the American Medical Association has examined the dosage and safety of a urolithin A supplement [1]. This study also examined urolithin A‘s effect on muscle endurance and specific health biomarkers. A randomized, controlled clinical trial This study is a
Puerarin Shows Promise in Fighting COPD in Cells
February 14, 2022
Publishing in Aging, a team of researchers has discovered how puerarin, an extract of kudzu, ameliorates chronic obstructive pulmonary disorder (COPD) signs in cellular cultures by limiting mitophagy: the consumption of mitochondria by cells. When autophagy isn’t a good thing Mitophagy is a subset of autophagy,
Supplement Combo Boosts Working Memory in Older People
January 5, 2022
An open-access human study published in Clinical Nutrition has found that a combination of supplements is beneficial for working memory. Identifying the dietary compounds Specific types of eating patterns have been associated with improved memory and cognition. The authors highlight some of the specific dietary components
What Is Quercetin? A Summary of Quercetin
December 20, 2021
Found in many fruits and vegetables, quercetin may have some potential in the context of aging. Here, we take a look at this natural antioxidant and popular dietary supplement. What is quercetin? Quercetin is a natural flavonoid, which makes it part of a large family of
What is Metformin? A Summary of N,N-dimethylbiguanide
November 17, 2021
We take a look at this diabetic drug that some researchers think may slow down aging. What is metformin? Metformin is a prescription drug and is available as a tablet or an oral solution. It is a commonly used first-line medication for the treatment of type
What is Rapamycin? A Summary of Rapamycin
October 8, 2021
We take a look at rapamycin and why some researchers think it could be useful in combating aging. What is rapamycin? Rapamycin is a macrolide, a class of antibiotic that includes erythromycin, roxithromycin, azithromycin, and clarithromycin. Rapamycin exhibits potent antitumor and immunosuppressive activity. Where is rapamycin
What is Nicotinamide Riboside? A Summary of NR
September 27, 2021
Nicotinamide riboside (NR) is part of the B3 vitamin family. Like other forms of vitamin B3, nicotinamide riboside gets converted into nicotinamide adenine dinucleotide (NAD+), a coenzyme essential for life. For this reason, it is often called a NAD+ precursor because it is part of the
What is Resveratrol? A Summary of Resveratrol
August 26, 2021
Probably best known for its presence in grapes and wine, this popular dietary supplement may have a few tricks up its sleeve. What is resveratrol? Resveratrol is a stilbenoid, a type of natural phenol. It is a phytoalexin, a growth-inhibiting substance created by plant tissues in
What is Spermidine? A Summary of Spermidine
August 6, 2021
Found in grapefruit, spermidine is one of the more interesting polyamines. Some research suggests that spermidine may slow down aging and promote healthy longevity. What is spermidine? Spermidine is a polyamine, meaning it has two or more primary amino groups. It is naturally occurring and is widely
What is Berberine? A Summary of Berberine Alkaloid
August 5, 2021
We take a look at berberine, a popular supplement in the life extension community that is often touted as being similar to metformin. What is berberine? Berberine is an ammonium salt from the protoberberine group of benzylisoquinoline alkaloids. It is part of a group of naturally
What is Magnesium? A Summary of Magnesium
July 31, 2021
Magnesium is a common element and is found in a variety of foods, but not everyone gets enough of this essential element, which is vital for cellular processes. What is magnesium? Magnesium is an important mineral which plays a key role in hundreds of enzyme reactions
What is Alpha-lipoic Acid? A Summary of ALA
July 24, 2021
Alpha-lipoic acid (also known as ALA) is a common supplement, and we take a look at it in the context of aging. What is alpha-lipoic acid? Alpha-lipoic acid is an organosulfur (an organic compound that contains sulfur) derived from caprylic acid (also known as octanoic acid).
What is Arginine? A Summary of L-Arginine
July 23, 2021
Arginine is a popular sports supplement, but could it also be useful in the context of healthy longevity? What is arginine? Arginine, also known as L-arginine, is an amino acid, a building block used to make proteins, that plays an important role in regulating blood flow.