Category: Interviews
Steve Horvath on the Present and Future of Epigenetic Clocks
August 8, 2022
Dr. Steve Horvath hardly needs an introduction, so we will be brief: he is the inventor of the epigenetic clock and, currently, principal investigator at Altos Labs. We talked about
Vadim Gladyshev on the Fundamentals of Aging
July 8, 2022
Vadim Gladyshev is a Professor of Medicine at Brigham and Women’s Hospital and Harvard Medical School, and he is one of the most prominent figures in geroscience today. We discussed
Extracellular Matrix in Aging with Professor Collin Ewald
July 4, 2022
Dr. Collin Ewald is a molecular biologist and a professor at the Swiss Federal Institute of Technology in Zürich (ETH). At ETH, Collin leads the Laboratory of Extracellular Matrix (ECM)
H+ DAO and Transhumanism with Dr. Natasha Vita-More
June 30, 2022
“Transhumanism is a philosophy, worldview, and a movement,” Dr. Natasha Vita-More states in the book “Transhumanism: What is it?” Essentially, it’s the idea of being able to move beyond being
Reprogramming Cells with Vittorio Sebastiano of Turn.bio
May 19, 2022
Vittorio Sebastiano is an Associate Professor (Research) of Obstetrics and Gynecology at Stanford University and one of the most prominent scientists in the emerging field of cellular reprogramming. He is
Discussing Crowd Funded Cures with Savva Kerdemelidis
May 17, 2022
We have written extensively about VitaDAO, a collective dedicated to community-governed, decentralized drug development. Probably the fastest and cheapest way to get geroprotective drugs to the market is by repurposing
João Pedro de Magalhães on Reprogramming and Aging Theories
May 13, 2022
Professor João Pedro de Magalhães leads the Genomics of Ageing and Rejuvenation Lab at the Institute of Inflammation and Ageing in the University of Birmingham. He is also CSO of
Prof. Richard Miller on the Interventions Testing Program
May 5, 2022
Richard A. Miller is a Professor of Pathology at the University of Michigan and the Director of Michigan’s Paul F. Glenn Center for Biology of Aging Research. He is also
Yuri Deigin on Cellular Reprogramming in Humans
May 4, 2022
In a recent press release, YouthBio Therapeutics announced that it has left stealth mode. YouthBio is a self-proclaimed longevity biotech company with a focus on developing gene therapies that reverse
Discussing Low-Dose Naltrexone with Sajad Zalzala
April 20, 2022
Dr. Sajad Zalzala, co-founder of AgelessRx, prescribes naltrexone for a variety of conditions and is currently enrolling patients in clinical trials for its effectiveness against the lingering effects of COVID-19
Dr. Steven Austad on Aging in Wild and Lab Animals
April 12, 2022
Dr. Steven Austad of the University of Alabama at Birmingham is not a typical geroscientist, or at least, he did not become one in a typical way. After obtaining his undergraduate
Raiany Romanni on the Ethical Aspects of Life Extension
April 1, 2022
Raiany Romanni is a Harvard Kennedy Fellow in Effective Altruism, an A360 Scholar, a Stanford Existential Risk Fellow, and a bioethicist. She is currently working on a non-fiction book aimed
Dr. Simon Melov on Single Cell Genomics
March 8, 2022
Dr. Simon Melov is a professor at the Buck Institute for Research on Aging. His lab is working on identifying the molecular hallmarks of aging, specifically in the context of
Dr. Pankaj Kapahi: “AGEs are a Trillion-Dollar Industry”
February 22, 2022
Dr. Pankaj Kapahi is a veteran geroscientist. His laboratory at the famous Buck Institute for Research on Aging is among the few that study advanced glycation end products (AGEs) and
Sonia Arrison: “Aging Is One of the Last Unifying Issues”
January 31, 2022
Sonia Arrison is an entrepreneur, investor, and best-selling author. Her book “100 Plus: How the Coming Age of Longevity Will Change Everything”, published in 2011, was one of the first
Steve Horvath on the Present and Future of Epigenetic Clocks
August 8, 2022
Dr. Steve Horvath hardly needs an introduction, so we will be brief: he is the inventor of the epigenetic clock and, currently, principal investigator at Altos Labs. We talked about the recent developments in this immensely important field, including pan-mammalian clocks, two-species clocks, and single-cell clocks,
Vadim Gladyshev on the Fundamentals of Aging
July 8, 2022
Vadim Gladyshev is a Professor of Medicine at Brigham and Women’s Hospital and Harvard Medical School, and he is one of the most prominent figures in geroscience today. We discussed various competing hypotheses on the nature of aging, the lack of the unified theory of aging
Extracellular Matrix in Aging with Professor Collin Ewald
July 4, 2022
Dr. Collin Ewald is a molecular biologist and a professor at the Swiss Federal Institute of Technology in Zürich (ETH). At ETH, Collin leads the Laboratory of Extracellular Matrix (ECM) Regeneration. Here, his research focuses on age-related ECM remodeling and related longevity interventions. We caught up
H+ DAO and Transhumanism with Dr. Natasha Vita-More
June 30, 2022
“Transhumanism is a philosophy, worldview, and a movement,” Dr. Natasha Vita-More states in the book “Transhumanism: What is it?” Essentially, it’s the idea of being able to move beyond being human, and finding solutions to living longer, healthier lives. Natasha is an Executive Director of Humanity+,
Reprogramming Cells with Vittorio Sebastiano of Turn.bio
May 19, 2022
Vittorio Sebastiano is an Associate Professor (Research) of Obstetrics and Gynecology at Stanford University and one of the most prominent scientists in the emerging field of cellular reprogramming. He is also co-founder and Scientific Advisory Board Chairman of Turn Biotechnologies, a cellular rejuvenation company based on
Discussing Crowd Funded Cures with Savva Kerdemelidis
May 17, 2022
We have written extensively about VitaDAO, a collective dedicated to community-governed, decentralized drug development. Probably the fastest and cheapest way to get geroprotective drugs to the market is by repurposing existing drugs, such as rapamycin, metformin, and acarbose. These drugs cost next to nothing, have a
João Pedro de Magalhães on Reprogramming and Aging Theories
May 13, 2022
Professor João Pedro de Magalhães leads the Genomics of Ageing and Rejuvenation Lab at the Institute of Inflammation and Ageing in the University of Birmingham. He is also CSO of YouthBio Therapeutics, a US-based biotech company that develops rejuvenation gene therapies based on partial reprogramming by
Prof. Richard Miller on the Interventions Testing Program
May 5, 2022
Richard A. Miller is a Professor of Pathology at the University of Michigan and the Director of Michigan’s Paul F. Glenn Center for Biology of Aging Research. He is also a driving force behind the ITP, the Interventions Testing Program, created in the early 2000s to
Yuri Deigin on Cellular Reprogramming in Humans
May 4, 2022
In a recent press release, YouthBio Therapeutics announced that it has left stealth mode. YouthBio is a self-proclaimed longevity biotech company with a focus on developing gene therapies that reverse the epigenetic alterations that cause us to age. The company is hoping to reverse cellular aging
Discussing Low-Dose Naltrexone with Sajad Zalzala
April 20, 2022
Dr. Sajad Zalzala, co-founder of AgelessRx, prescribes naltrexone for a variety of conditions and is currently enrolling patients in clinical trials for its effectiveness against the lingering effects of COVID-19 as well as for longevity. We caught up with him to discuss the progress in this
Dr. Steven Austad on Aging in Wild and Lab Animals
April 12, 2022
Dr. Steven Austad of the University of Alabama at Birmingham is not a typical geroscientist, or at least, he did not become one in a typical way. After obtaining his undergraduate degree in English literature, Steven spent several years on jobs such as a wild animal trainer
Raiany Romanni on the Ethical Aspects of Life Extension
April 1, 2022
Raiany Romanni is a Harvard Kennedy Fellow in Effective Altruism, an A360 Scholar, a Stanford Existential Risk Fellow, and a bioethicist. She is currently working on a non-fiction book aimed at catalyzing the ethics of longevity research, while suggesting that aging is the costliest of all
Dr. Simon Melov on Single Cell Genomics
March 8, 2022
Dr. Simon Melov is a professor at the Buck Institute for Research on Aging. His lab is working on identifying the molecular hallmarks of aging, specifically in the context of cellular senescence. Recently, the lab published a paper in which it announced a discovery of a
Dr. Pankaj Kapahi: “AGEs are a Trillion-Dollar Industry”
February 22, 2022
Dr. Pankaj Kapahi is a veteran geroscientist. His laboratory at the famous Buck Institute for Research on Aging is among the few that study advanced glycation end products (AGEs) and the many ways in which they affect aging. Dr. Kapahi’s company, Juvify, produces GLYLO, a supplement
Sonia Arrison: “Aging Is One of the Last Unifying Issues”
January 31, 2022
Sonia Arrison is an entrepreneur, investor, and best-selling author. Her book “100 Plus: How the Coming Age of Longevity Will Change Everything”, published in 2011, was one of the first to bring the topic of longevity to the general public’s attention. Sonia is also founder of