Category: News
Senolytics Alleviate Age‐Related Cognitive Decline
January 22, 2021
A new study by a team of researchers, including Dr. Kirkland of Mayo Clinic, shows the effect of whole-body senolytic treatment on the health and function of the brain. This
Partial Reprogramming Rejuvenates Human Cells by 30 Years
January 21, 2021
Researchers from the Reik lab at the Babraham Institute have used the four Yamanaka reprogramming factors (OSKM) in order to epigenetically rejuvenate cells by 30 years, according to one epigenetic
Investigating the Link Between COVID-19 and Telomeres
January 20, 2021
New research published in Aging has analyzed the telomeres of patients hospitalized due to COVID-19. As the COVID-19 pandemic has spread rapidly across the globe, many researchers have pivoted their
AI Identifies Senescent Cells and Tests New Drugs
January 19, 2021
A group of scientists has created a neural network that identifies senescent cells by their morphology and can be used for senolytic drug screening [1]. Image recognition is a showcase
Alpha-Ketoglutarate Delays Age‐Related Fertility Decline
January 18, 2021
Alpha-ketoglutarate (AKG) is a popular dietary and sports supplement frequently used in the bodybuilding world, but interest in this molecule has more recently reached the aging research field for its
Looking Forward to a Productive 2021 in Aging Research
January 15, 2021
The world of rejuvenation biotechnology is a rapidly changing and ever developing place. As with any disruptive technology, the challenges are significant and include not only the technical aspects of
A Genetic Pathway for Preventing Hearing Loss
January 14, 2021
Activation of a genetic pathway controlled by the NRF2 gene reduces age-related hearing loss, according to a new study [1]. In the long run, drugs or treatments that target this
NOVOS Explains Its New Nutraceutical
January 13, 2021
NOVOS is a nutraceutical company focused on developing science-based nutraceuticals to slow down aging and will offer tests to track people’s aging processes to get a better picture of their
Senescent Cells Recruit Sympathetic Nerves
January 13, 2021
Researchers publishing in Frontiers of Aging Neuroscience Journal have discovered a new way in which senescent cells contribute to aging and chronic disease. The sympathetic nervous system in age-related diseases
Exercise Found to Have Anti-Senescence Effect
January 12, 2021
A new review paper delivers evidence that exercise, a powerful anti-aging tool, may be a natural senolytic [1]. Progress in the field of senolytics has been mixed. After the initial
Arterial Stiffening Correlates With Cognitive Decline
January 11, 2021
Today, we want to highlight the results of a recent long-term study, which collected data over a four-year period to investigate the link between aortic stiffening and cognitive decline, including
Senolytics Reduce Gut Inflammation in Mice
January 8, 2021
A few years ago, a team at Mayo Clinic led by Dr. James Kirkland treated mice with the cancer drug dasatinib and the popular dietary supplement quercetin, with results suggesting
Groundbreaking New Therapy for Progeria
January 7, 2021
A gene editing technique published in Nature has proven to be effective in a mouse model of Hutchinson–Gilford progeria syndrome (HGPS). A single error causes tremendous damage HGPS is a
A Cause of Genomic Instability Discovered
January 6, 2021
Research further illuminating the mechanisms of impaired DNA damage repair associated with aging has recently been published in the journal Aging. DNA damage repair is reduced as we age While
Tina Woods: A Social Entrepreneur in the Longevity Field
January 5, 2021
Tina Woods is a UK-based founder of several social enterprises in healthcare and longevity and the author of the book Live Longer with AI, which we recently reviewed. In this
Senolytics Alleviate Age‐Related Cognitive Decline
January 22, 2021
A new study by a team of researchers, including Dr. Kirkland of Mayo Clinic, shows the effect of whole-body senolytic treatment on the health and function of the brain. This follows up on previous Mayo Clinic research led by Dr. James Kirkland. That experiment treated mice
Partial Reprogramming Rejuvenates Human Cells by 30 Years
January 21, 2021
Researchers from the Reik lab at the Babraham Institute have used the four Yamanaka reprogramming factors (OSKM) in order to epigenetically rejuvenate cells by 30 years, according to one epigenetic clock. Reprogramming just beyond the threshold Previous experiments have shown that while exposing cells to the
Investigating the Link Between COVID-19 and Telomeres
January 20, 2021
New research published in Aging has analyzed the telomeres of patients hospitalized due to COVID-19. As the COVID-19 pandemic has spread rapidly across the globe, many researchers have pivoted their existing research to help characterize and fight the disease. Longevity researchers have been particularly interested in
AI Identifies Senescent Cells and Tests New Drugs
January 19, 2021
A group of scientists has created a neural network that identifies senescent cells by their morphology and can be used for senolytic drug screening [1]. Image recognition is a showcase triumph of artificial intelligence. While this problem was considered extremely hard to crack in previous decades,
Alpha-Ketoglutarate Delays Age‐Related Fertility Decline
January 18, 2021
Alpha-ketoglutarate (AKG) is a popular dietary and sports supplement frequently used in the bodybuilding world, but interest in this molecule has more recently reached the aging research field for its potential to slow down aging. AKG is a naturally occurring endogenous intermediary metabolite, which means that
Looking Forward to a Productive 2021 in Aging Research
January 15, 2021
The world of rejuvenation biotechnology is a rapidly changing and ever developing place. As with any disruptive technology, the challenges are significant and include not only the technical aspects of developing these technologies but also the hurdles of societal acceptance of the desirability of longer, healthier
A Genetic Pathway for Preventing Hearing Loss
January 14, 2021
Activation of a genetic pathway controlled by the NRF2 gene reduces age-related hearing loss, according to a new study [1]. In the long run, drugs or treatments that target this pathway could help us keep our hearing sharp as we get older. It’s getting harder and
NOVOS Explains Its New Nutraceutical
January 13, 2021
NOVOS is a nutraceutical company focused on developing science-based nutraceuticals to slow down aging and will offer tests to track people’s aging processes to get a better picture of their health. The company offers two nutraceutical products, NOVOS Core and NOVOS Boost. Core contains 12 ingredients
Senescent Cells Recruit Sympathetic Nerves
January 13, 2021
Researchers publishing in Frontiers of Aging Neuroscience Journal have discovered a new way in which senescent cells contribute to aging and chronic disease. The sympathetic nervous system in age-related diseases Our nervous systems are divided into the central nervous system, which consists of the brain and
Exercise Found to Have Anti-Senescence Effect
January 12, 2021
A new review paper delivers evidence that exercise, a powerful anti-aging tool, may be a natural senolytic [1]. Progress in the field of senolytics has been mixed. After the initial hype that had spawned dozens of startups, enthusiasm has waned somewhat in the wake of the
Arterial Stiffening Correlates With Cognitive Decline
January 11, 2021
Today, we want to highlight the results of a recent long-term study, which collected data over a four-year period to investigate the link between aortic stiffening and cognitive decline, including dementia. During aging, our blood vessels become increasingly stiff and lose their flexibility, and the cells
Senolytics Reduce Gut Inflammation in Mice
January 8, 2021
A few years ago, a team at Mayo Clinic led by Dr. James Kirkland treated mice with the cancer drug dasatinib and the popular dietary supplement quercetin, with results suggesting that the combination was able to destroy senescent cells. This combination was part of the first
Groundbreaking New Therapy for Progeria
January 7, 2021
A gene editing technique published in Nature has proven to be effective in a mouse model of Hutchinson–Gilford progeria syndrome (HGPS). A single error causes tremendous damage HGPS is a well-known disease that causes visible aging and early death in children. In progeria, the lamina that
A Cause of Genomic Instability Discovered
January 6, 2021
Research further illuminating the mechanisms of impaired DNA damage repair associated with aging has recently been published in the journal Aging. DNA damage repair is reduced as we age While we have multiple mechanisms for repairing genomic damage, one type of damage, double-strand breaks, is particularly
Tina Woods: A Social Entrepreneur in the Longevity Field
January 5, 2021
Tina Woods is a UK-based founder of several social enterprises in healthcare and longevity and the author of the book Live Longer with AI, which we recently reviewed. In this interview, Tina shares valuable insights on how social entrepreneurship works in our field, what governments can