Category: News
Plant Flavonoid Naringenin Is a Senotherapeutic
September 28, 2020
Researchers have published a new animal study showing that the plant flavonoid naringenin may be useful in targeting problematic senescent cells in the brain. Ribes meyeri (also known as Ribes
Rick Kiessig Discusses VTose, a Broad-Spectrum Antiviral
September 25, 2020
Recently, we had the opportunity to interview Rick Kiessig, the co-founder of Kimer Med, a company developing a broad-spectrum antiviral that has the potential to destroy a wide range of
Mitochondrial Mutations Associated with Fertility Decline
September 24, 2020
According to new research, mutations accumulate in the mitochondrial DNA of egg cells, leading to changes in cellular metabolism, which result in reduced fertility. The study also showed that Nicotinamide
A New Microporous Membrane for Skin Regeneration
September 23, 2020
A new study published in Archives of Dermatological Research has shown that a novel microporous membrane can promote the regeneration of healthy human skin. Skin regeneration Skin regeneration has been
Microtubule Stabilization Ameliorates Alzheimer’s Symptoms
September 22, 2020
A group of researchers has been able to ameliorate Alzheimer-like pathologies in mice by using a microtubule-stabilizing compound [1]. Cellular highways Microtubules (MTs) are tiny pipe-like structures that are made
A Link Between the Microbiome, Heat, and Osteoporosis
September 21, 2020
Researchers from the University of Geneva have shown that a warm environment improves bone strength and highlights a related link with gut microbiome composition. These findings also pave the way
New iPhone App Measures Biological Age
September 18, 2020
A new app created by Hong Kong-based Deep Longevity might help you stay in your prime longer, keep your mind sharp, and maintain habits that keep your biological age lower
Senolytic Reverses Chemotherapy-Induced Neuropathy in Mice
September 17, 2020
Researchers have discovered that removing senescent-like neurons alleviates peripheral neuropathy caused by cisplatin, a powerful chemotherapy drug, in mice. Cisplatin As the researchers of this study explain, cisplatin is a
BMP4 and VEGF Promote Bone Regeneration
September 16, 2020
Because of bone’s natural self-healing abilities, it has provided regenerative medicine with some of its earliest successes. However, as with many tissues, the defects that can be treated are currently limited in size.
Delivering MicroRNA to Cells Ameliorates Inflammaging
September 15, 2020
A group of researchers has found that extracellular vesicles carrying a specific type of microRNA can attenuate age-related inflammation and increase immune response following flu vaccination in mice [1]. Extracellular
Why NAD+ Declines During Aging – Part 2
September 14, 2020
This is part 2 of a series focused on the age-related decline of NAD+; if you have not read the previous part, you can find it here. Today, we are
Methylation Clocks that Measure the Biological Age of Cats
September 11, 2020
Today, we have something a little bit different: progress in aging biomarkers but, this time, for cats! The race has been on for some years now to create biomarkers that
Caloric Restriction Improves DNA Repair in Mice
September 10, 2020
A short-term caloric restriction diet enhanced a DNA repair process known as non-homologous end joining. These results may partially explain how caloric restriction and similar diets increase lifespan and healthspan
Tissue Engineering and Regenerative Medicine in Longevity
September 9, 2020
This is part one of a new weekly series focusing on recent advancements in the field of regenerative medicine. The field of tissue engineering and regenerative medicine Tissue engineering and
Brown Fat Transplantation Reduces Obesity in Mice
September 8, 2020
A group of researchers has used CRISPR to create energy-dissipating brown adipocytes (fat cells) from white preadipocytes. The new cells were then shown to alleviate obesity in mice [1]. Obesity:
Plant Flavonoid Naringenin Is a Senotherapeutic
September 28, 2020
Researchers have published a new animal study showing that the plant flavonoid naringenin may be useful in targeting problematic senescent cells in the brain. Ribes meyeri (also known as Ribes meyeri maxim) is a native plant to central Asia, Mongolia and Northeast Afghanistan and is part
Rick Kiessig Discusses VTose, a Broad-Spectrum Antiviral
September 25, 2020
Recently, we had the opportunity to interview Rick Kiessig, the co-founder of Kimer Med, a company developing a broad-spectrum antiviral that has the potential to destroy a wide range of viruses. Its drug, known as VTose, is a variant of an older antiviral drug known as
Mitochondrial Mutations Associated with Fertility Decline
September 24, 2020
According to new research, mutations accumulate in the mitochondrial DNA of egg cells, leading to changes in cellular metabolism, which result in reduced fertility. The study also showed that Nicotinamide mononucleotide (NMN) treatment can restore the metabolic balance in aging mouse oocytes, rescuing fertility. Defective eggs
A New Microporous Membrane for Skin Regeneration
September 23, 2020
A new study published in Archives of Dermatological Research has shown that a novel microporous membrane can promote the regeneration of healthy human skin. Skin regeneration Skin regeneration has been a major goal for tissue engineering and regenerative medicine. However, natural skin is difficult to recapitulate
Microtubule Stabilization Ameliorates Alzheimer’s Symptoms
September 22, 2020
A group of researchers has been able to ameliorate Alzheimer-like pathologies in mice by using a microtubule-stabilizing compound [1]. Cellular highways Microtubules (MTs) are tiny pipe-like structures that are made mostly of the polymerized protein tubulin. They constitute an important part of the cytoskeleton, a network
A Link Between the Microbiome, Heat, and Osteoporosis
September 21, 2020
Researchers from the University of Geneva have shown that a warm environment improves bone strength and highlights a related link with gut microbiome composition. These findings also pave the way for novel therapies for the treatment of osteoporosis. Turning up the heat Osteoporosis is an age-related
New iPhone App Measures Biological Age
September 18, 2020
A new app created by Hong Kong-based Deep Longevity might help you stay in your prime longer, keep your mind sharp, and maintain habits that keep your biological age lower than your chronological age. Introducing Young.ai It has been an increasing trend in recent years for
Senolytic Reverses Chemotherapy-Induced Neuropathy in Mice
September 17, 2020
Researchers have discovered that removing senescent-like neurons alleviates peripheral neuropathy caused by cisplatin, a powerful chemotherapy drug, in mice. Cisplatin As the researchers of this study explain, cisplatin is a chemotherapy drug that works by causing platination in nuclear DNA, which leads to cellular failure, senescence,
BMP4 and VEGF Promote Bone Regeneration
September 16, 2020
Because of bone’s natural self-healing abilities, it has provided regenerative medicine with some of its earliest successes. However, as with many tissues, the defects that can be treated are currently limited in size.
Delivering MicroRNA to Cells Ameliorates Inflammaging
September 15, 2020
A group of researchers has found that extracellular vesicles carrying a specific type of microRNA can attenuate age-related inflammation and increase immune response following flu vaccination in mice [1]. Extracellular vesicles (EVs) are an important part of intercellular communication. These tiny nanoscale bubbles are secreted by
Why NAD+ Declines During Aging – Part 2
September 14, 2020
This is part 2 of a series focused on the age-related decline of NAD+; if you have not read the previous part, you can find it here. Today, we are continuing our look at some of the evidence for the age-related decline of NAD+ in humans
Methylation Clocks that Measure the Biological Age of Cats
September 11, 2020
Today, we have something a little bit different: progress in aging biomarkers but, this time, for cats! The race has been on for some years now to create biomarkers that can accurately measure biological age. Having such biomarkers is critical in the development of therapies that
Caloric Restriction Improves DNA Repair in Mice
September 10, 2020
A short-term caloric restriction diet enhanced a DNA repair process known as non-homologous end joining. These results may partially explain how caloric restriction and similar diets increase lifespan and healthspan in a wide range of organisms. Eat less, live longer Caloric restriction – that is, reduced
Tissue Engineering and Regenerative Medicine in Longevity
September 9, 2020
This is part one of a new weekly series focusing on recent advancements in the field of regenerative medicine. The field of tissue engineering and regenerative medicine Tissue engineering and regenerative medicine (TERM) is a large and rapidly growing field that has implications for the field
Brown Fat Transplantation Reduces Obesity in Mice
September 8, 2020
A group of researchers has used CRISPR to create energy-dissipating brown adipocytes (fat cells) from white preadipocytes. The new cells were then shown to alleviate obesity in mice [1]. Obesity: the nemesis of longevity Obesity is one of humanity’s deadliest enemies. It is a known comorbidity