Category: News
Three Groundbreaking Longevity Startups
January 9, 2020
There are lots of exciting companies working in the aging field, and it’s a great time to tell you about three of the more interesting ones. Most of these companies
Revel Pharma to Develop Glucosepane Breakers
January 8, 2020
Some pleasant news has recently arrived: Revel Pharmaceuticals has successfully completed a seed round in order to begin developing therapeutics that target glucosepane crosslinks, which are a proposed reason why
Treating Glaucoma with Senolytics
January 6, 2020
New research suggests that senolytic drugs, which remove harmful senescent cells that accumulate during aging, may be an effective therapy for glaucoma, a common age-related condition that leads to loss
Looking Back at 2019 – and Forward to 2020
January 3, 2020
2019 is quite a milestone for LEAF; this will be our fourth year of bringing you the latest industry news, organizing online events, hosting our annual conference in New York,
Anti-Aging Drug Rejuvenates Oral Health
December 19, 2019
A new study shows that short-term treatment with the common organ rejection drug rapamycin reverses periodontal bone loss, attenuates inflammation, and makes the oral microbiome revert to a more youthful
Greg Potter on Biohacking and Lifestyle
December 17, 2019
We had the opportunity to interview Greg Potter, Ph.D., a researcher of lifestyle factors in health throughout life, at Biohacking Conference Moscow, which was hosted at the Congress Centre Technopolis
Tryptophan as a Therapeutic Target for Inflammaging
December 9, 2019
A new open access paper takes a look at tryptophan and the role that it plays in the dysfunction of the immune system in the context of the age-related changes
DNA Testing Company Veritas Genetics Suspends U.S. Operations
December 6, 2019
After experiencing financial issues, DNA testing company Veritas Genetics has announced the suspension of its U.S. operations in an unexpected announcement on December 4th 2019. The company is perhaps best
Brian Kennedy on Rapamycin, mTOR, and Interventions
December 4, 2019
If humans ever reach an average lifespan of well over 100 years, what is going to happen? Are we going to be bored with such long lives? “Well,” says Prof.
Age-Related Gut Microbiome Changes Happen Early in Life
December 3, 2019
A new study suggests that harmful changes to the population and diversity of our gut bacteria may occur when we are as young as our mid 30s, which can have
The Gut Microbiome’s Influence on Skeletal Muscle Mass
December 2, 2019
Researcher Dr. Michael Lustgarten has recently published a compact and very readable review that focuses on the role of the gut microbiome and its influence on skeletal muscle mass. The
Positive Results of a Human Trial for Skin Aging
November 27, 2019
The results of a small human clinical trial focused on skin aging have been published, and they are positive. A topical application of rapamycin, an FDA-approved drug that is used
Irresponsible Marketing Surrounds Telomerase Trials
November 26, 2019
Recently, Libella Gene Therapeutics has announced that it will be running a patient-paid trial in Colombia with an eye-watering $1 million USD price tag on enrollment. Patient-paid trial likely to
Gut Microbes Promote Neurogenesis and Longevity Hormone
November 21, 2019
The relationship between health and the microorganisms living in the gut has increasingly reached the spotlight in the last few years, and a new study led by researchers at Nanyang
Disappointing Results for ResTORbio Human Trial
November 18, 2019
ResTORbio announced on Friday 15th that its current phase 3 drug trial for respiratory tract infections did not achieve its primary goal. The drug showed promise in earlier phases of
Three Groundbreaking Longevity Startups
January 9, 2020
There are lots of exciting companies working in the aging field, and it’s a great time to tell you about three of the more interesting ones. Most of these companies are a while away from human trials yet, but their innovations could possibly be truly game
Revel Pharma to Develop Glucosepane Breakers
January 8, 2020
Some pleasant news has recently arrived: Revel Pharmaceuticals has successfully completed a seed round in order to begin developing therapeutics that target glucosepane crosslinks, which are a proposed reason why we age, develop diseases such as diabetes, and suffer from stiffened arteries and hypertension. In the
Treating Glaucoma with Senolytics
January 6, 2020
New research suggests that senolytic drugs, which remove harmful senescent cells that accumulate during aging, may be an effective therapy for glaucoma, a common age-related condition that leads to loss of vision. In the short term, inflammation serves a useful purpose, as it helps to spur
Looking Back at 2019 – and Forward to 2020
January 3, 2020
2019 is quite a milestone for LEAF; this will be our fourth year of bringing you the latest industry news, organizing online events, hosting our annual conference in New York, and crowdsourcing important research projects over at lifespan.io. We have been incredibly busy and, as has
Anti-Aging Drug Rejuvenates Oral Health
December 19, 2019
A new study shows that short-term treatment with the common organ rejection drug rapamycin reverses periodontal bone loss, attenuates inflammation, and makes the oral microbiome revert to a more youthful state in old mice. What is rapamycin? Rapamycin (also known as sirolimus) is a macrolide, a
Greg Potter on Biohacking and Lifestyle
December 17, 2019
We had the opportunity to interview Greg Potter, Ph.D., a researcher of lifestyle factors in health throughout life, at Biohacking Conference Moscow, which was hosted at the Congress Centre Technopolis Moscow on September 19th. In a provocative 2017 publication, Serge Faguet claimed to have spent $200,000
Tryptophan as a Therapeutic Target for Inflammaging
December 9, 2019
A new open access paper takes a look at tryptophan and the role that it plays in the dysfunction of the immune system in the context of the age-related changes that occur in the microbiome [1]. The microbiome The gut microbiome is a complex ecosystem of
DNA Testing Company Veritas Genetics Suspends U.S. Operations
December 6, 2019
After experiencing financial issues, DNA testing company Veritas Genetics has announced the suspension of its U.S. operations in an unexpected announcement on December 4th 2019. The company is perhaps best known for being co-founded by renowned Harvard University geneticist George Church and has been working towards
Brian Kennedy on Rapamycin, mTOR, and Interventions
December 4, 2019
If humans ever reach an average lifespan of well over 100 years, what is going to happen? Are we going to be bored with such long lives? “Well,” says Prof. Brian Kennedy of the National University of Singapore, “If you ask me: ‘Do I want to
Age-Related Gut Microbiome Changes Happen Early in Life
December 3, 2019
A new study suggests that harmful changes to the population and diversity of our gut bacteria may occur when we are as young as our mid 30s, which can have serious implications for health and longevity. The microbiome The gut microbiome is a complex and ever-changing
The Gut Microbiome’s Influence on Skeletal Muscle Mass
December 2, 2019
Researcher Dr. Michael Lustgarten has recently published a compact and very readable review that focuses on the role of the gut microbiome and its influence on skeletal muscle mass. The gut microbiome The microbiome describes a varied community of bacteria, archaea, eukarya, and viruses that inhabit
Positive Results of a Human Trial for Skin Aging
November 27, 2019
The results of a small human clinical trial focused on skin aging have been published, and they are positive. A topical application of rapamycin, an FDA-approved drug that is used to combat organ rejection during donor transplants and targets the mechanistic target of rapamycin (mTOR) pathway,
Irresponsible Marketing Surrounds Telomerase Trials
November 26, 2019
Recently, Libella Gene Therapeutics has announced that it will be running a patient-paid trial in Colombia with an eye-watering $1 million USD price tag on enrollment. Patient-paid trial likely to cause backlash The topic of patient-paid trials often stirs up considerable debate among the research community,
Gut Microbes Promote Neurogenesis and Longevity Hormone
November 21, 2019
The relationship between health and the microorganisms living in the gut has increasingly reached the spotlight in the last few years, and a new study led by researchers at Nanyang Technological University, Singapore (NTU Singapore) sheds more light on the gut microbiome and how it can
Disappointing Results for ResTORbio Human Trial
November 18, 2019
ResTORbio announced on Friday 15th that its current phase 3 drug trial for respiratory tract infections did not achieve its primary goal. The drug showed promise in earlier phases of testing, but sadly failed to reduce the incidence of respiratory tract infections in patients aged 65