Category: News

Rejuvenation Roundup August 2024

Rejuvenation Roundup August 2024

Summer’s at its end, but rejuvenation biotechnology is still heating up, with researchers discovering ways of vastly improving mouse lifespan and conducting a recruitment drive for young scientists. Here’s how

DNA hourglass

Some Cells Age Much Faster Than Others

In Stem Cell Reports, researchers have described how cell subpopulations and division affect the results of epigenetic clocks. Good, but never perfect As these researchers note, epigenetic clocks have had

Osteoporosis

Why Bone Destruction Is Accelerated with Aging

Researchers have described a relationship between the NAD+ regulator CD38, mitochondrial function, and the gradual destruction of bone in Aging Cell. Inflammation up, bone mass down It is well known

Alopecia

A Phase 2 Clinical Trial for Hair Loss

Los Angeles-based Pelage Pharmaceuticals has just announced a Phase 2a clinical trial for the treatment of androgenetic alopecia, also known as pattern baldness. It is thought that up to 50%

Tricky balance

Fighting Inflammation May Cause More Senescence

A researcher publishing in Biogerontology has reviewed the literature on the relationship between cellular senescence and the immune system, finding that dwindling immune surveillance allows senescent cells to accumulate. The

Pancreas

Combination Therapy Works Against Pancreatic Cancer in Mice

In a new study, a multi-prong treatment combined with a clever delivery method has shown promise against one of the deadliest cancers [1]. Lethal and barely treatable Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest types of cancer. It is rarely diagnosed early and very

Ground coffee

Caffeic Acid Variant May Suppress Bone Deterioration

In Aging, researchers have described how a derivative of caffeic acid inhibits osteoclasts, the cells that break down bone. A modification of a tested compound We have recently published new information on what triggers the imbalance between bone-destroying osteoclasts and bone-building osteoblasts. This is a well-known

Rejuvenation Roundup August 2024

Rejuvenation Roundup August 2024

Summer’s at its end, but rejuvenation biotechnology is still heating up, with researchers discovering ways of vastly improving mouse lifespan and conducting a recruitment drive for young scientists. Here’s how the field was advanced in August. Interviews Michael Antonov: from Oculus to Longevity Biotech: After Oculus

DNA hourglass

Some Cells Age Much Faster Than Others

In Stem Cell Reports, researchers have described how cell subpopulations and division affect the results of epigenetic clocks. Good, but never perfect As these researchers note, epigenetic clocks have had successes in analyzing the impact of things that impact biological age, such as the effects of

Aged skin

Skin Aging and Cellular Mobility at the Protein Level

In Aging, researchers have described how the changing production of skin cells’ proteins is a core part of their age-related decline. Understanding why skin cells lose their function In healthy skin, dermal fibroblasts produce the proteins needed to maintain the extracellular matrix (ECM), the network of

Lab mouse

NNMT Inhibitor Improves Muscle Function in Aged Mice

A recent paper has reported on improving muscle function in aged mice through combined treatment of exercise and the inhibition of NNMT, an enzyme involved in NAD+ metabolism [1]. Age-related muscle loss Muscle loss is a common problem in the aging population. Studies estimate that “after

Weekend backpackers

Weekend-Oriented Physical Activity Superior for Brain Health

According to a new study, “weekend warriors”, people who have most of their physical activity over one or two days a week, enjoy the most robust risk reduction for several brain health-related conditions [1]. Couch potato, except on weekends Exercise is universally necessary to stay healthy

Osteoporosis

Why Bone Destruction Is Accelerated with Aging

Researchers have described a relationship between the NAD+ regulator CD38, mitochondrial function, and the gradual destruction of bone in Aging Cell. Inflammation up, bone mass down It is well known that CD38, an enzyme that takes away NAD+, increases with age. The gradual depletion of this

Manuka Tree

Manuka Honey Effective Against Breast Cancer in Mice

UCLA scientists have shown that Manuka, an exclusive honey variety, can quench estrogen receptor-positive breast cancer in vitro and in vivo [1]. Honey, kill that cancer Breast cancer remains the deadliest type of cancer in women, claiming more than 40 thousand victims a year in the

Alopecia

A Phase 2 Clinical Trial for Hair Loss

Los Angeles-based Pelage Pharmaceuticals has just announced a Phase 2a clinical trial for the treatment of androgenetic alopecia, also known as pattern baldness. It is thought that up to 50% of men experience hair loss as a result of pattern baldness by age 50. In this

HIIT training could be a way to combat cognitive decline as we age.

High-Intensity Interval Training Improves Cognition

Cognitive decline is one of the risks associated with getting older, but new research suggests there may be a way to fight back. A new study suggests that high-intensity interval training improves spatial learning and maintains brain volume and connectivity [1]. Shrinking aging brain One of

Peter Diamandis is a major influence on the field of aging and rejuvenation research.

Peter Diamandis: “Stay Healthy, Anti-Aging Tech is Coming”

To many people, Peter Diamandis needs no introduction, and to the rest, it’s going to be a long one. To put it as concisely as possible, Peter is a serial entrepreneur and investor in several fields, from commercial space flight to longevity biotech; a visionary speaker

Tricky balance

Fighting Inflammation May Cause More Senescence

A researcher publishing in Biogerontology has reviewed the literature on the relationship between cellular senescence and the immune system, finding that dwindling immune surveillance allows senescent cells to accumulate. The immune system needs to be deadly On the cellular level, the bodies of vertebrates are brutal

Elderly eating healthy food

Anti-Inflammatory Diets Mitigate Risk of Dementia

A new study suggests that an anti-inflammatory diet can significantly reduce the risk of dementia and delay its onset even in people with existing cardiometabolic diseases [1]. Is it too late to lower the risk? Cardiometabolic diseases, such as type 2 diabetes, heart attack, and stroke,

Elderly man with large waistline

Inflammation May Drive Fat Distribution in Older People

A new study published in Aging Cell has detailed what happens to individual fat cells in white adipose tissue (WAT) as they age. When fat is more than just fat Previous research has described WAT as an organ in its own right, functioning not only as