Category: News
Some Medications Associated with Improved Aging Biomarkers
April 10, 2024
The authors of a recent study published in Aging Cell tested 21 groups of medication used by the elderly and reported that some of them impact aging biomarkers [1]. Repurposing
Reprogramming Helps Old Mice Produce More Neurons
April 9, 2024
Scientists have found that partial cellular reprogramming, both full-body and restricted to specific brain regions, rescues neurogenesis in the brains of old mice [1]. Cells going back in time Partial
Finding Senolytics to Stop Lung Disease
April 8, 2024
Researchers publishing in the Journal of Clinical Investigation have developed a new method of screening for compounds, and they found one that appears to directly attack senescent cells involved in
Scientists Discover a New Mechanism of Age-Related Obesity
April 5, 2024
A new study suggests that the reason why aging is associated with obesity lies in specific neurons found in the brain [1]. Tell that to the brain It is often hard
Small Molecules Reverse Many Age-Related Changes in Cells
April 4, 2024
A team of Harvard researchers has published a paper in eLife detailing the downstream effects of small molecule partial cellular reprogramming. Rejuvenating cells from the ground up We have recently
SENS Research Foundation and lifespan.io Announce Merge
April 3, 2024
NEW YORK, April 3, 2024 – In a groundbreaking announcement set to impact the future of longevity research and outreach, two historic longevity nonprofits – SENS Research Foundation and lifespan.io
Senolytic CAR T Cells Rescue Intestinal Aging in Mice
April 3, 2024
Scientists have demonstrated that CAR T cells can be employed against senescent intestinal stem cells, improving regeneration and ameliorating age-related symptoms such as “leaky gut” [1]. Cell-on-cell warfare Cellular senescence
More Social Connections Associated with Slower Aging
April 3, 2024
Recent research has contributed to the growing body of evidence regarding social isolation, loneliness, and biological aging [1]. Social isolation is not generally screened for During doctor visits, patients are
Longevity and DeSci Recap – March 2024
April 2, 2024
Welcome back for the latest edition of the Longevity and DeSci Recap. This March has seen a swarm of activity as the longevity and DeSci world has sprung to renewed
Longevity Gets Political at an Unprecedented DC Event
April 2, 2024
The longevity community has always been a niche one, but many of its members realize this is not how we defeat aging. This goal requires immense resources as well as
The Epigenetic Similarities Between E-Cigarettes and Smoking
April 1, 2024
The authors of a new paper in Cancer Research have published the surprising finding that cigarettes and e-cigarettes have some similar effects on DNA methylation that have been reported to
Nicklas Brendborg on How Jellyfish Age Backwards
April 1, 2024
The quest for eternal youth, encapsulated in Dr. Malcolm’s fictional yet profound declaration that “Life finds a way,” mirrors humanity’s age-old fascination with longevity. This fascination isn’t new; as Nicolas
Rejuvenation Roundup March 2024
April 1, 2024
April Fool’s Day is here yet again, but the ongoing research and clinical trials are no joke at all. Here’s what’s happened in March. LEAF News Team and activities Stephanie
Restoring Lymphoid-Myeloid Balance Boosts Immunity in Mice
March 29, 2024
A new study suggests that depleting a subset of stem cells that overproduces myeloid cells can rescue age-related immunosenescence [1]. Thrown off balance Immunosenescence, the gradual decline in the immune
Popular Antioxidants Don’t Work Against Bone Loss in Mice
March 28, 2024
In Aging, researchers have published negative results on the long-term use of methylene blue and mitoquinone (MitoQ), two popular antioxidants, to sustain bone health in mice. Oxidative stress and bone
Some Medications Associated with Improved Aging Biomarkers
April 10, 2024
The authors of a recent study published in Aging Cell tested 21 groups of medication used by the elderly and reported that some of them impact aging biomarkers [1]. Repurposing existing drugs to fight aging The search for drugs that slow aging includes finding new compounds
Reprogramming Helps Old Mice Produce More Neurons
April 9, 2024
Scientists have found that partial cellular reprogramming, both full-body and restricted to specific brain regions, rescues neurogenesis in the brains of old mice [1]. Cells going back in time Partial reprogramming improves various health metrics and increases lifespan in animal models [2]. For instance, Dr. David
Finding Senolytics to Stop Lung Disease
April 8, 2024
Researchers publishing in the Journal of Clinical Investigation have developed a new method of screening for compounds, and they found one that appears to directly attack senescent cells involved in lung fibrosis. A disease of senescence Senescent cells are a major part of an age-related lung
Scientists Discover a New Mechanism of Age-Related Obesity
April 5, 2024
A new study suggests that the reason why aging is associated with obesity lies in specific neurons found in the brain [1]. Tell that to the brain It is often hard to lose weight, and it becomes harder with age. While it seems simple enough to eat
Small Molecules Reverse Many Age-Related Changes in Cells
April 4, 2024
A team of Harvard researchers has published a paper in eLife detailing the downstream effects of small molecule partial cellular reprogramming. Rejuvenating cells from the ground up We have recently reported on a review of partial cellular reprogramming that used a cocktail of small molecules named
SENS Research Foundation and lifespan.io Announce Merge
April 3, 2024
NEW YORK, April 3, 2024 – In a groundbreaking announcement set to impact the future of longevity research and outreach, two historic longevity nonprofits – SENS Research Foundation and lifespan.io (Lifespan Extension Advocacy Foundation) – have unveiled plans to merge, upon completion of regulatory approvals. lifespan.io,
Senolytic CAR T Cells Rescue Intestinal Aging in Mice
April 3, 2024
Scientists have demonstrated that CAR T cells can be employed against senescent intestinal stem cells, improving regeneration and ameliorating age-related symptoms such as “leaky gut” [1]. Cell-on-cell warfare Cellular senescence is a heterogeneous phenomenon in which cells stop dividing and malfunction, driving up inflammation. While senescent
More Social Connections Associated with Slower Aging
April 3, 2024
Recent research has contributed to the growing body of evidence regarding social isolation, loneliness, and biological aging [1]. Social isolation is not generally screened for During doctor visits, patients are often screened for many physical conditions. However, screening for social isolation in the clinic is not
Longevity and DeSci Recap – March 2024
April 2, 2024
Welcome back for the latest edition of the Longevity and DeSci Recap. This March has seen a swarm of activity as the longevity and DeSci world has sprung to renewed life. Between the many upcoming conferences, latest investment news, and innovations happening at the Vitalia pop-up
Longevity Gets Political at an Unprecedented DC Event
April 2, 2024
The longevity community has always been a niche one, but many of its members realize this is not how we defeat aging. This goal requires immense resources as well as political and regulatory changes that can only be obtained at a national level. With all our
The Epigenetic Similarities Between E-Cigarettes and Smoking
April 1, 2024
The authors of a new paper in Cancer Research have published the surprising finding that cigarettes and e-cigarettes have some similar effects on DNA methylation that have been reported to lead to cancer. Harm reduction might not truly reduce harm It is well-known that cigarettes are
Nicklas Brendborg on How Jellyfish Age Backwards
April 1, 2024
The quest for eternal youth, encapsulated in Dr. Malcolm’s fictional yet profound declaration that “Life finds a way,” mirrors humanity’s age-old fascination with longevity. This fascination isn’t new; as Nicolas Brendborg’s “Jellyfish Age Backwards – Nature’s Secrets to Longevity” expounds; it’s as ancient as the epic
Rejuvenation Roundup March 2024
April 1, 2024
April Fool’s Day is here yet again, but the ongoing research and clinical trials are no joke at all. Here’s what’s happened in March. LEAF News Team and activities Stephanie Dainow Speaks at Rejuvenation Startup Summit 2024: Stephanie Dainow, Executive Director of lifespan.io was a speaker
Restoring Lymphoid-Myeloid Balance Boosts Immunity in Mice
March 29, 2024
A new study suggests that depleting a subset of stem cells that overproduces myeloid cells can rescue age-related immunosenescence [1]. Thrown off balance Immunosenescence, the gradual decline in the immune system’s abilities, is one of the hallmarks of aging [2]. Moreover, many scientists view it as
Popular Antioxidants Don’t Work Against Bone Loss in Mice
March 28, 2024
In Aging, researchers have published negative results on the long-term use of methylene blue and mitoquinone (MitoQ), two popular antioxidants, to sustain bone health in mice. Oxidative stress and bone health Previous work has found that oxidative stress, which is commonly associated with age-related disease and