Category: News

RR August 23

Rejuvenation Roundup August 2023

EARD2023, the Longevity + DeSci Summit, is over, but the work its speakers have been doing continues. Here’s what’s happened on the aging research front in August. LEAF News Team

Longevity DeSci Aug 2023

Longevity and DeSci Recap – August 2023

On the Longevity and DeSci Recap, you’ll discover the latest interviews, insights, and research in the longevity tech sphere over the past month and learn more about topics including blockchain,

Gene analysis

A Gene Behind a Key Senescence Biomarker

A paper published in GeroScience has described a gene responsible for a key biomarker of cellular senescence. A widely used biomarker Senescence-associated beta-galactosidase (SA-ß-gal) is the most widely used and

Mouse on hand

Senolytics Have Sex-Dependent Effects on Young Mice

In a research paper published in GeroScience, researchers investigated the impact of senolytics on young mice and found some surprising results [1]. Senescent cell removal and other properties Senolytics, when

EARD2023 Photo

Science and Advocacy at EARD 2023

After three years in digital format due to COVID concerns, one of the oldest longevity conferences was again welcoming attendants in New York City. Ending Age-Related Diseases (EARD), organized by

Cat heart

Treating Enlarged Hearts in Cats with Rapamycin

Researchers publishing in Journal of the American Veterinary Medical Association have conducted a feline clinical trial finding that rapamycin is effective against heart enlargement in cats. A well-known drug for

How Spaceflight Alters the Rate of Aging

A review published in Aging Cell has explored the impact of spaceflight on human and other organisms’ health and aging [1]. Hazards of spaceflight Will sending humans to space make

Effect of AMD

A Protective Mechanism Against AMD

A paper published in Aging explains the relationship of long noncoding RNAs, which change with aging, to age-related macular degeneration (AMD). A disease of deposits and aging This paper begins

Osteoblasts

Figuring Out Why Stem Cells Won’t Build Bone

Researchers publishing in Aging have uncovered some of the molecular mechanisms behind why mesenchymal stem cells (MSCs) do and don’t differentiate into bone-building osteoblasts, unlocking a potential new approach to

The Journal Club is a monthly livestream hosted by Dr. Oliver Medvedik which covers the latest aging research papers.

Join us for Journal Club August 2023

The Journal Club for August returns live to the lifespan.io Facebook channel on September 5th at 12:00 Eastern hosted by Dr. Oliver Medvedik. This time we are taking a look

Curcumin

Antioxidants Rescue Cognitive Decline in Mice

Scientists have found that EGCG and curcumin, two well-known antioxidants, are effective both alone and especially in combination in a mouse model of cognitive decline induced by oxidative stress [1].

Biomarkers

Biomarker Study Returns Surprising Results

Researchers publishing in Biogerontology have tested multiple biomarkers in an effort to use them as proxies for aging, and some of their findings were surprising. A simple study with direct

RR August 23

Rejuvenation Roundup August 2023

EARD2023, the Longevity + DeSci Summit, is over, but the work its speakers have been doing continues. Here’s what’s happened on the aging research front in August. LEAF News Team and activities EARD 2023: After three years in digital format due to COVID concerns, one of the

Longevity DeSci Aug 2023

Longevity and DeSci Recap – August 2023

On the Longevity and DeSci Recap, you’ll discover the latest interviews, insights, and research in the longevity tech sphere over the past month and learn more about topics including blockchain, DAOs, cryptocurrency, DeSci, and events that have been happening over the past month. The fall breeze

Gene analysis

A Gene Behind a Key Senescence Biomarker

A paper published in GeroScience has described a gene responsible for a key biomarker of cellular senescence. A widely used biomarker Senescence-associated beta-galactosidase (SA-ß-gal) is the most widely used and most definitive biomarker of cellular senescence [1]. However, unlike other senescence-related biomarkers, such as p21 [2],

Mouse on hand

Senolytics Have Sex-Dependent Effects on Young Mice

In a research paper published in GeroScience, researchers investigated the impact of senolytics on young mice and found some surprising results [1]. Senescent cell removal and other properties Senolytics, when given to older mice, clear senescent cells. Senolytics such as fisetin and quercetin also have anti-inflammatory

EARD2023 Photo

Science and Advocacy at EARD 2023

After three years in digital format due to COVID concerns, one of the oldest longevity conferences was again welcoming attendants in New York City. Ending Age-Related Diseases (EARD), organized by lifespan.io for the sixth time, kept with modern ideas by using a hybrid format that combined

Cat heart

Treating Enlarged Hearts in Cats with Rapamycin

Researchers publishing in Journal of the American Veterinary Medical Association have conducted a feline clinical trial finding that rapamycin is effective against heart enlargement in cats. A well-known drug for a well-known problem Rapamycin, also known as sirolimus, is one of the most well-known and commonly

Lobsters do not age like we do, perhaps we can learn to do the same.

Is Immortality Possible or Is Aging Inevitable?

  “Could humans become immortal?” is something we get asked quite often, and the answer depends on what exactly you mean. When it comes to immortality, what you mean is important Whether human immortality is possible greatly depends on how you define it. If you define

Elderly bicycling

Diversity in Daily Activities Might Slow Cognitive Decline

A new study suggests that greater diversity of everyday activities is associated with a slower rate of age-related cognitive decline, independently of the amount of physical activity [1]. Variety or quantity? It is widely accepted that being cognitively and socially active can slow down age-associated cognitive

Naked Mole Rat

Utilizing One of the Naked Mole Rat’s Abilities

Publishing in Nature, a team of researchers including Vadim Gladyshev, Steve Horvath, and Vera Gorbunova has investigated the role of hyaluronan, which naked mole rats have in abundance, as a protective mechanism in a mouse model. An established mechanism Naked mole rats are notably resistant to

How Spaceflight Alters the Rate of Aging

A review published in Aging Cell has explored the impact of spaceflight on human and other organisms’ health and aging [1]. Hazards of spaceflight Will sending humans to space make them age slower or faster? Will they be healthier, or will their health suffer? As space

Effect of AMD

A Protective Mechanism Against AMD

A paper published in Aging explains the relationship of long noncoding RNAs, which change with aging, to age-related macular degeneration (AMD). A disease of deposits and aging This paper begins with a discussion of AMD and its prevalence. AMD is the most common cause of vision

Osteoblasts

Figuring Out Why Stem Cells Won’t Build Bone

Researchers publishing in Aging have uncovered some of the molecular mechanisms behind why mesenchymal stem cells (MSCs) do and don’t differentiate into bone-building osteoblasts, unlocking a potential new approach to osteoporosis. A matter of cellular fate MSCs are downstream of pluripotent stem cells: they can differentiate

The Journal Club is a monthly livestream hosted by Dr. Oliver Medvedik which covers the latest aging research papers.

Join us for Journal Club August 2023

The Journal Club for August returns live to the lifespan.io Facebook channel on September 5th at 12:00 Eastern hosted by Dr. Oliver Medvedik. This time we are taking a look at a paper where researchers have transfered a lifespan and healthspan boosting mechanism from the naked

Curcumin

Antioxidants Rescue Cognitive Decline in Mice

Scientists have found that EGCG and curcumin, two well-known antioxidants, are effective both alone and especially in combination in a mouse model of cognitive decline induced by oxidative stress [1]. Not the usual stress Oxidative stress results mostly from molecules called reactive oxygen species (ROS), which

Biomarkers

Biomarker Study Returns Surprising Results

Researchers publishing in Biogerontology have tested multiple biomarkers in an effort to use them as proxies for aging, and some of their findings were surprising. A simple study with direct measurements Unlike other association studies that are used to evaluate biomarkers of aging, this study did