Category: News
What Is Quercetin? A Summary of Quercetin
December 20, 2021
Found in many fruits and vegetables, quercetin may have some potential in the context of aging. Here, we take a look at this natural antioxidant and popular dietary supplement. What
NewLimit: A New Biotech Working on Epigenetic Aging
December 17, 2021
Two investors, including a co-founder of Coinbase, have announced a new biotech venture that aims to solve aging by studying its epigenetic aspects. New kid on the block Long gone
Old Serum Shown to Kill Brain Stem Cells
December 16, 2021
A study published in Aging and Disease has shown how exposure to old serum causes hippocampal progenitor cells (HPCs), which form new neurons, to die. Drawing and testing serum from
Plant-Based Diet Linked To Reduced Leaky Gut Syndrome
December 15, 2021
The MaPLE trial in Italy investigated whether or not increasing fruits and vegetables decreases leaky gut syndrome [1]. Background This study examines increased intestinal permeability (leaky gut) in adults 60
Epigenetic Clock Shows Association With Cardiovascular Aging
December 15, 2021
A new study published in Mechanisms of Ageing and Development has found correlations between cardiovascular aging and a measure of epigenetic age acceleration [1]. Can epigenetic clocks predict cardiovascular disease?
A Grape seed Extract Slows Aging In Mice
December 14, 2021
Studying grape seed extract, scientists have discovered a new senomorphic compound that enhances chemotherapy and prolongs lifespan and healthspan in mice [1]. Nature’s drugstore Many drugs have come to us
Olive Derivative Fights Epigenetic Kidney Aging
December 13, 2021
Researchers publishing in Aging Cell have discovered how and why oleuropein (OLP), a polyphenol derived from olives, ameliorates epigenetic kidney aging. Upregulation and downregulation Like nearly everything in biology, this
Viagra Identified as a Candidate Drug for Alzheimer’s
December 10, 2021
After sifting through 1,600 FDA-approved drugs, scientists have shown that Viagra is significantly correlated with lower Alzheimer’s disease risk [1]. Re-repurposing Viagra? Viagra (sildenafil) is one of the most recognizable
Chinese Licorice Plant Extract Restores Fat Stem Cells
December 9, 2021
Researchers publishing in Aging have reported that licochalcone A (LA), a flavonoid that originates from Chinese licorice, restores human adipose-derived stem cells (hADSCs) in cell culture. Reported positive effects Previous
Demonstration That Cord Blood Improves Progeria
December 9, 2021
A new case report published in the International Journal of Molecular Sciences highlights cardiovascular improvements in a patient with Hutchinson-Gilford progeria treated with umbilical cord blood. A case study using
Hyperbaric Oxygen Causes Transcriptomic Changes
December 8, 2021
Transcriptomic results have been published regarding the Shamir Medical Center longitudinal study on hyperbaric oxygen therapy (HBOT), which was conducted between 2016 and 2020 on 35 healthy adults aged 64
Late-Life Treatment Extends Nematode Lifespan by Two-Fold
December 7, 2021
Scientists have managed to extend the lifespan of C. elegans nematode worms by as much as 135% by blocking an insulin-related pathway very late in life [1]. The long-lived mutants
Building a Universal Immunotherapy for Cancer
December 6, 2021
Researchers publishing in Cell Reports Medicine have described a method of using off-the-shelf, allogeneic immune cells as cancer therapy. Overcoming the hurdles of allogeneic cells Allogeneic cells come from other
Gitcoin Launches Crypto Funding Round for Longevity
December 3, 2021
Gitcoin is a platform dedicated to supporting the development of open-source Web3 software – decentralized architecture based upon blockchain technology – and the funding of “public goods” projects that are
Alpha-Ketoglutarate Decreases Biological Age in Human Study
December 3, 2021
A commercially available alpha-ketoglutarate-based supplement has been shown to roll back biological age by 7 years on average in a retrospective human study [1]. Live slower, die later Though metformin and
What Is Quercetin? A Summary of Quercetin
December 20, 2021
Found in many fruits and vegetables, quercetin may have some potential in the context of aging. Here, we take a look at this natural antioxidant and popular dietary supplement. What is quercetin? Quercetin is a natural flavonoid, which makes it part of a large family of
NewLimit: A New Biotech Working on Epigenetic Aging
December 17, 2021
Two investors, including a co-founder of Coinbase, have announced a new biotech venture that aims to solve aging by studying its epigenetic aspects. New kid on the block Long gone are the times when longevity biotech companies were scarce and poorly funded. Today, barely a week
Old Serum Shown to Kill Brain Stem Cells
December 16, 2021
A study published in Aging and Disease has shown how exposure to old serum causes hippocampal progenitor cells (HPCs), which form new neurons, to die. Drawing and testing serum from living people To begin their study, the researchers examined a middle-aged to old (MATO) cohort ranging
Plant-Based Diet Linked To Reduced Leaky Gut Syndrome
December 15, 2021
The MaPLE trial in Italy investigated whether or not increasing fruits and vegetables decreases leaky gut syndrome [1]. Background This study examines increased intestinal permeability (leaky gut) in adults 60 years and older [1]. Age has been reported to be a risk factor for increased intestinal
Epigenetic Clock Shows Association With Cardiovascular Aging
December 15, 2021
A new study published in Mechanisms of Ageing and Development has found correlations between cardiovascular aging and a measure of epigenetic age acceleration [1]. Can epigenetic clocks predict cardiovascular disease? One way researchers test the validity and usefulness of epigenetic clocks is to compare their outputs
A Grape seed Extract Slows Aging In Mice
December 14, 2021
Studying grape seed extract, scientists have discovered a new senomorphic compound that enhances chemotherapy and prolongs lifespan and healthspan in mice [1]. Nature’s drugstore Many drugs have come to us from the world of plants, including promising geroprotective molecules such as resveratrol. However, identifying specific components
Olive Derivative Fights Epigenetic Kidney Aging
December 13, 2021
Researchers publishing in Aging Cell have discovered how and why oleuropein (OLP), a polyphenol derived from olives, ameliorates epigenetic kidney aging. Upregulation and downregulation Like nearly everything in biology, this specific part of kidney aging results from a chain of events. Here, the researchers show that
Viagra Identified as a Candidate Drug for Alzheimer’s
December 10, 2021
After sifting through 1,600 FDA-approved drugs, scientists have shown that Viagra is significantly correlated with lower Alzheimer’s disease risk [1]. Re-repurposing Viagra? Viagra (sildenafil) is one of the most recognizable drugs in the world. Yet, sildenafil’s hailed effect on erectile dysfunction was discovered serendipitously. Originally, sildenafil
Chinese Licorice Plant Extract Restores Fat Stem Cells
December 9, 2021
Researchers publishing in Aging have reported that licochalcone A (LA), a flavonoid that originates from Chinese licorice, restores human adipose-derived stem cells (hADSCs) in cell culture. Reported positive effects Previous research on Licochalcone A has discovered that it has anti-inflammatory and anti-tumor effects [1], reduces obesity
Demonstration That Cord Blood Improves Progeria
December 9, 2021
A new case report published in the International Journal of Molecular Sciences highlights cardiovascular improvements in a patient with Hutchinson-Gilford progeria treated with umbilical cord blood. A case study using umbilical cord blood Cell therapy has shown potential in treating cardiovascular disease, which is also the
Hyperbaric Oxygen Causes Transcriptomic Changes
December 8, 2021
Transcriptomic results have been published regarding the Shamir Medical Center longitudinal study on hyperbaric oxygen therapy (HBOT), which was conducted between 2016 and 2020 on 35 healthy adults aged 64 and older [1]. Background Recently, we discussed misconceptions from the media on research developing on HBOT
Late-Life Treatment Extends Nematode Lifespan by Two-Fold
December 7, 2021
Scientists have managed to extend the lifespan of C. elegans nematode worms by as much as 135% by blocking an insulin-related pathway very late in life [1]. The long-lived mutants Back in the late 80s and early 90s, experiments with C. elegans, tiny nematode worms, became
Building a Universal Immunotherapy for Cancer
December 6, 2021
Researchers publishing in Cell Reports Medicine have described a method of using off-the-shelf, allogeneic immune cells as cancer therapy. Overcoming the hurdles of allogeneic cells Allogeneic cells come from other sources than the individual being treated. As recipients of organ donations know, if the immune system
Gitcoin Launches Crypto Funding Round for Longevity
December 3, 2021
Gitcoin is a platform dedicated to supporting the development of open-source Web3 software – decentralized architecture based upon blockchain technology – and the funding of “public goods” projects that are intended to benefit everyone. Of course, one such public good is the extension of healthy human
Alpha-Ketoglutarate Decreases Biological Age in Human Study
December 3, 2021
A commercially available alpha-ketoglutarate-based supplement has been shown to roll back biological age by 7 years on average in a retrospective human study [1]. Live slower, die later Though metformin and rapamycin are getting most of the attention in the longevity field today, alpha-ketoglutarate (AKG) has emerged