Category: News

Champions of Coronavirus

Fighting COVID-19 by Counteracting Aging

A research paper that has just been peer reviewed and published in Nature has described how disrupting an immune pathway that is upregulated in aging decreases the lethality of COVID-19

Elderly professor

The Growing Increase in Cognitive Reserve

A study published in Brain Sciences has shown that mild cognitive impairment is less than half as common now as it was twenty years ago. Two cohorts, one study This

Clinical trial

Clinical Trials Targeting Aging

A miniature review of clinical trials targeting aging was published in Frontiers in Aging by Dr. Morten Scheibye-Knudsen and colleagues [1]. This review specifically focuses on interventions that have shown

Cell targeting

Using Gene Expression to Target Senescent Cells

An open access study published in iScience has discussed the development of senolytics to target particular genes that are upregulated in cellular senescence. Understanding senescence, cell by cell In our

Guinea pig

Tuberculosis Is Associated with Epigenetic Aging

Publishing in Aging, a team of researchers has explained the relationship between tuberculosis (TB) and multiple aspects of aging, including epigenetic alterations and the senescence-associated secretory phenotype (SASP). A disease

Simon Melov

Dr. Simon Melov on Single Cell Genomics

Dr. Simon Melov is a professor at the Buck Institute for Research on Aging. His lab is working on identifying the molecular hallmarks of aging, specifically in the context of

Champions of Coronavirus

Fighting COVID-19 by Counteracting Aging

A research paper that has just been peer reviewed and published in Nature has described how disrupting an immune pathway that is upregulated in aging decreases the lethality of COVID-19 in a mouse model. Mice with COVID-19 As the researchers explain, normal mice do not use

Elderly and dog

Dog Ownership Lowers Risk of Disability in Old Age

In a new population study, scientists show that dog ownership is associated with a lower risk of developing disability in old age, though it does not affect all-cause mortality [1]. 1500+ dogs, and some cats too What can be more stereotypical than an old lady with

Elderly professor

The Growing Increase in Cognitive Reserve

A study published in Brain Sciences has shown that mild cognitive impairment is less than half as common now as it was twenty years ago. Two cohorts, one study This study used data from the Interdisciplinary Longitudinal Study of Adult Development and Aging (ILSE), which began

Microglia

Microglia Depletion Decreases Neuroinflammation in Mice

Scientists show that when done right, partial elimination of microglia, the immune cells of the brain, lowers age-related inflammation and cellular senescence [1]. Aging makes microglia bitter Brain health is of utmost importance for geroscientists, since the brain is the one organ that cannot be replaced,

Clinical trial

Clinical Trials Targeting Aging

A miniature review of clinical trials targeting aging was published in Frontiers in Aging by Dr. Morten Scheibye-Knudsen and colleagues [1]. This review specifically focuses on interventions that have shown strong clinical evidence that they impact aging. Caloric restriction We have previously discussed the effects of

Dina Radenkovic

Dina Radenkovic on the Root Cause of Gender Inequality

Our interviewee today holds that female reproductive aging, or ovarian aging, is accelerated compared to other organs and that it has a deep impact both on the lives and health of women and on our society as a whole. Nevertheless, ovarian aging continues to be underresearched,

Cell targeting

Using Gene Expression to Target Senescent Cells

An open access study published in iScience has discussed the development of senolytics to target particular genes that are upregulated in cellular senescence. Understanding senescence, cell by cell In our earlier interview with Simon Melov of the Buck Institute, the lead researcher of this paper, Dr.

Guinea pig

Tuberculosis Is Associated with Epigenetic Aging

Publishing in Aging, a team of researchers has explained the relationship between tuberculosis (TB) and multiple aspects of aging, including epigenetic alterations and the senescence-associated secretory phenotype (SASP). A disease known to cause long-term harm Tuberculosis, a disease that has proliferated around the world, kills 1.4

Mouse genes

Long-Term Cellular Reprogramming Causes Rejuvenation in Mice

Scientists have shown that in vivo partial cellular reprogramming can be safe and effective in an animal model, although the rejuvenation was mostly limited to long-term treatments and two tissue types [1]. There and back again Cellular reprogramming sounds like a technology from Star Trek, and

Meat on plate

Meat Consumption Increases Risk of Some Types of Cancer

In a new population study, scientists have found more evidence that consuming a lot of meat might not be a good idea, though the association between meat and cancer depends on multiple factors [1]. Diet and health Given that lifestyle changes may be the only anti-aging

Sunlight

Vitamin D Dosing Safety in a Randomized, Controlled Trial

New data has been released from the Vitamin D Type 2 Diabetes (D2d) study [1]. This study is a randomized, controlled trial that includes overweight and obese people studied at 22 academic medical centers in the United States. This data was collected between October 2013 and

Simon Melov

Dr. Simon Melov on Single Cell Genomics

Dr. Simon Melov is a professor at the Buck Institute for Research on Aging. His lab is working on identifying the molecular hallmarks of aging, specifically in the context of cellular senescence. Recently, the lab published a paper in which it announced a discovery of a

Immune cell warrior

SENS Researchers Culture Immune Cells to Fight Senescence

Publishing in Aging, a team of researchers from SENS Research Foundation has described a new method of enriching natural killer (NK) cells to fight senescent cells. Culturing NK cells to fight senescence Previous experiments have shown that natural killer (NK) cells are partially responsible for the

Exercise Improves Cognition Depending on Type and Amount

In a new review paper, scientists show that exercise can alleviate age-related cognitive decline, but not all types of exercise are created equal [1]. Watch your head Lifestyle choices, such as exercise and diet, are the most powerful anti-aging interventions currently available to us, and they

Gut bacteria

Gut Viruses Found to Improve Cognition in Humans

A study published in Cell Host & Microbe has found that members of the Cuadovirales viral order positively affect cognition in multiple species, including humans. Viruses in the human body, but not human viruses Cuadovirales is an order of bacteriophages, which infect bacteria rather than animal