Category: News
Epigenetic Age Acceleration Is Linked to Hearing Loss
January 19, 2022
A study published in Frontiers in Aging Neuroscience examined the relationship between epigenetic age acceleration and hearing [1]. Since 1958, a team of researchers from the National Institute on Aging
Quercetin Improves Bone Regeneration in Older Rats
January 19, 2022
A new study in ACS Applied Materials and Interfaces used a combined geroscience and tissue engineering approach to regenerate bone in aged rats [1]. Replacement or rejuvenation? Too often, tissue
Fasting-Mimicking Diet Helps Fight Cancer
January 18, 2022
In the first human trial of its kind, scientists showed that a fasting-mimicking diet can work synergistically with conventional therapies in cancer patients, altering their metabolisms and reshaping their immune
OKN-007 Protects Mouse Spinal Cords
January 17, 2022
Publishing in GeroScience, a team of Oklahoma City researchers has found that a nitrone compound with a low molecular weight, OKN-007, maintains motor neuron functionality in the spinal cords of
Dr. Brian Kennedy: From Sickcare to Healthcare
January 14, 2022
Dr. Brian Kennedy is a longevity heavyweight: a former President of the Buck Institute, currently a Distinguished Professor in the Department of Biochemistry and Physiology at the National University of
Key Parkinson’s Protein Required for Immune Function
January 13, 2022
A study published in Cell Reports has found α-synuclein, the fundamental protein of Parkinson’s disease, to be critical in immune function. The gut-brain axis as a channel for disease Parkinson’s
The Effects of Metformin and Lifestyle on Mortality
January 12, 2022
An outcomes study conducted by the Diabetes Prevention Program (DPP) has examined the effects of lifestyle interventions and the popular diabetes drug metformin on all-cause mortality. Background The original DPP
Isthmin 1 as a Biomarker and Therapeutic Target for Aging
January 12, 2022
A recent study published in Biogerontology has discovered a potential new aging biomarker and longevity therapeutic target [1]. Isthmin 1 (Ism1) in aging fish Ism1 is not a well-known protein,
Genetically Engineered T Cells Reduce Cardiac Fibrosis
January 11, 2022
Scientists have created genetically engineered T cells that target activated cardiac fibroblasts in a transient manner, alleviating symptoms of cardiac injury [1]. Engineered immune cells CAR T cell therapy is
Debate Rages on the Inclusion of Old Age in the ICD-11
January 10, 2022
A significant debate has originated regarding the inclusion of MG2A, a code for old age, in the ICD-11 for Mortality and Morbidity Statistics. What is the ICD-11? The 11th revision
New Combination Treatment Shows Promise Against Dementia
January 7, 2022
Scientists have combined the popular antibiotic rifampicin with resveratrol to create a possible preventative treatment for age-related dementias [1]. Oligomers, not plaques? Age-related dementias, such as Alzheimer’s disease, still defy
Osteopontin Bone Remodeling May Be Key to Arthritis
January 6, 2022
A study published in Aging has found that osteopontin’s effects on bone remodeling may be at least partially responsible for osteoarthritis. What is osteopontin? Osteopontin is a glycoprotein found in
Supplement Combo Boosts Working Memory in Older People
January 5, 2022
An open-access human study published in Clinical Nutrition has found that a combination of supplements is beneficial for working memory. Identifying the dietary compounds Specific types of eating patterns have
The Effects of Spermidine on Heart Mitochondria in Mice
January 5, 2022
The latest research published in the Journal of Anatomy found that spermidine alters the morphology of mitochondria in aged mouse heart tissue [1]. Mitochondrial dysfunction in the aging heart Evidence
Creating Political Action to Increase Healthy Human Lifespan
January 4, 2022
A recent online discussion panel revealed some valuable insights into the political aspects of increasing healthy human lifespans. Perhaps the most exciting part of the panel involves the idea that
Epigenetic Age Acceleration Is Linked to Hearing Loss
January 19, 2022
A study published in Frontiers in Aging Neuroscience examined the relationship between epigenetic age acceleration and hearing [1]. Since 1958, a team of researchers from the National Institute on Aging Intramural Research program has been conducting the Baltimore Longitudinal Study of Aging (BLSA). The BLSA study
Quercetin Improves Bone Regeneration in Older Rats
January 19, 2022
A new study in ACS Applied Materials and Interfaces used a combined geroscience and tissue engineering approach to regenerate bone in aged rats [1]. Replacement or rejuvenation? Too often, tissue engineering and longevity therapeutics are viewed as competing strategies – two different paths to potentially combat
Fasting-Mimicking Diet Helps Fight Cancer
January 18, 2022
In the first human trial of its kind, scientists showed that a fasting-mimicking diet can work synergistically with conventional therapies in cancer patients, altering their metabolisms and reshaping their immune systems [1]. What happens when you fast? Fasting is shaping up to be a powerful addition
OKN-007 Protects Mouse Spinal Cords
January 17, 2022
Publishing in GeroScience, a team of Oklahoma City researchers has found that a nitrone compound with a low molecular weight, OKN-007, maintains motor neuron functionality in the spinal cords of aging mice. Prior research OKN-007 is not new in the literature. This is a nitrone compound,
Dr. Brian Kennedy: From Sickcare to Healthcare
January 14, 2022
Dr. Brian Kennedy is a longevity heavyweight: a former President of the Buck Institute, currently a Distinguished Professor in the Department of Biochemistry and Physiology at the National University of Singapore, a co-editor of Aging Cell, and one of the researchers behind a recent study of
Key Parkinson’s Protein Required for Immune Function
January 13, 2022
A study published in Cell Reports has found α-synuclein, the fundamental protein of Parkinson’s disease, to be critical in immune function. The gut-brain axis as a channel for disease Parkinson’s disease, which causes damage to the portion of the brain responsible for movement, is widely known
The Effects of Metformin and Lifestyle on Mortality
January 12, 2022
An outcomes study conducted by the Diabetes Prevention Program (DPP) has examined the effects of lifestyle interventions and the popular diabetes drug metformin on all-cause mortality. Background The original DPP was conducted at 27 centers in the United States from 1996 to 2001. Building upon this
Isthmin 1 as a Biomarker and Therapeutic Target for Aging
January 12, 2022
A recent study published in Biogerontology has discovered a potential new aging biomarker and longevity therapeutic target [1]. Isthmin 1 (Ism1) in aging fish Ism1 is not a well-known protein, but it has been shown to play a role in multiple aspects of biology. It contributes
Genetically Engineered T Cells Reduce Cardiac Fibrosis
January 11, 2022
Scientists have created genetically engineered T cells that target activated cardiac fibroblasts in a transient manner, alleviating symptoms of cardiac injury [1]. Engineered immune cells CAR T cell therapy is a much-touted novel technique that makes use of an organism’s own immune system. CAR stands for
Debate Rages on the Inclusion of Old Age in the ICD-11
January 10, 2022
A significant debate has originated regarding the inclusion of MG2A, a code for old age, in the ICD-11 for Mortality and Morbidity Statistics. What is the ICD-11? The 11th revision of the International Classification of Diseases, which goes into effect this month, is managed by the
New Combination Treatment Shows Promise Against Dementia
January 7, 2022
Scientists have combined the popular antibiotic rifampicin with resveratrol to create a possible preventative treatment for age-related dementias [1]. Oligomers, not plaques? Age-related dementias, such as Alzheimer’s disease, still defy current treatment options, impeding attempts to increase human lifespan. According to the theory of competing risks,
Osteopontin Bone Remodeling May Be Key to Arthritis
January 6, 2022
A study published in Aging has found that osteopontin’s effects on bone remodeling may be at least partially responsible for osteoarthritis. What is osteopontin? Osteopontin is a glycoprotein found in the extracellular matrix of bone tissue. This is a cytokine that is used in intercellular communication,
Supplement Combo Boosts Working Memory in Older People
January 5, 2022
An open-access human study published in Clinical Nutrition has found that a combination of supplements is beneficial for working memory. Identifying the dietary compounds Specific types of eating patterns have been associated with improved memory and cognition. The authors highlight some of the specific dietary components
The Effects of Spermidine on Heart Mitochondria in Mice
January 5, 2022
The latest research published in the Journal of Anatomy found that spermidine alters the morphology of mitochondria in aged mouse heart tissue [1]. Mitochondrial dysfunction in the aging heart Evidence for mitochondrial dysfunction as a driver of aging has been growing in recent years. As we
Creating Political Action to Increase Healthy Human Lifespan
January 4, 2022
A recent online discussion panel revealed some valuable insights into the political aspects of increasing healthy human lifespans. Perhaps the most exciting part of the panel involves the idea that getting politicians to support longevity/aging therapeutics might not be as hard as people may think. Giving