Category: News
What is Arginine? A Summary of L-Arginine
July 23, 2021
Arginine is a popular sports supplement, but could it also be useful in the context of healthy longevity? What is arginine? Arginine, also known as L-arginine, is an amino acid,
Teasing Apart the Effects of Aging and COVID-19
July 22, 2021
Researchers have used a big data approach to disentangle cellular and physiological changes that are specific to COVID-19 from those caused by aging [1]. Identifying these improves our understanding of
Senescent Cells, p65, and a Possible Treatment for Cancer
July 21, 2021
A report in the Journal of Cell Science has outlined different stages of cellular senescence alongside a mechanism that reverses it, along with a potential new treatment for glioblastoma. Old
Enriched Environments Youthen the Brains of Mice
July 20, 2021
A study published in Nature Communications has shown that an environment rich in stimuli changes the epigenetics of the mouse hippocampus, making the brains of aged mice more like those
HDAC Inhibitors Linked to Cellular Senescence
July 19, 2021
A study published in Aging has shown that inhibiting histone deacetylases (HDACs), an approach used for treating cancer and other diseases, can lead to cellular senescence. What is a histone,
PulseChain Airdrop Raises $20m for SENS
July 17, 2021
The SENS Research Foundation has apparently already raised four times its annual income thanks to the PulseChain Airdrop. The PulseChain airdrop supporting aging research Richard Heart, the founder of HEX,
Loss of Peptide Not Amyloid Plaques a New Alzheimer’s Target
July 16, 2021
A recent study, led by the University of Cincinnati in collaboration with the Karolinska Institute in Sweden, challenges the popular amyloid hypothesis that has dominated Alzheimer’s research for decades. Amyloid
Engineering Cells to Avoid Immune Detection in Transplants
July 15, 2021
Gene editing can make stem cells invisible to the immune system, making it possible to carry out cell therapy transplants without suppressing the patients’ immune response [1]. Help me help
The Enormous Economic Benefits of Targeting Aging
July 14, 2021
Using Peter Pan, Wolverine, and a powerful economic model, a trio of prominent scientists argues that slowing aging can bring gargantuan economic benefits – an order of magnitude bigger than
NMN Enhances Aerobic Capacity in Amateur Runners
July 14, 2021
A clinical trial of endurance runners recently published in the Journal of the International Society of Sports Nutrition found nicotinamide mononucleotide (NMN) to increase several measures of aerobic capacity. Could
Telomere Loss And The Development Of Fibrosis
July 13, 2021
A new study published in Aging has shown a link between a reduction in telomerase reverse transcriptase (TERT), the gene that allows for telomere maintenance, and the development of myofibroblasts,
Senolytics Improve Spinal Cord Recovery in Mice
July 12, 2021
A new study published in Cell Reports has shown that the senolytic navitoclax (ABT-263) helps mice heal from spinal cord injuries [1]. The difference between mice and zebrafish The zebrafish
Senolytics Show Positive Results in Phase 1 Clinical Trial
July 9, 2021
Leading the pack is never easy, but today, UNITY Biotechnology is back with some positive news for senolytics. Being first is not always easy UNITY Biotechnology is a company that
Castration Lengthens Lifespan of Sheep by Altering Androgens
July 8, 2021
Researchers have shown that castration makes male sheep live longer, and they’ve also used genomic data to get a basic understanding of the mechanism behind this longevity [1]. While castration
Niacin Tested Against Parkinson’s Disease
July 7, 2021
A clinical trial on the effectiveness of niacin supplementation in Parkinson’s disease patients has recently been published in Frontiers in Aging Neuroscience. The link between niacin and Parkinson’s disease Niacin
What is Arginine? A Summary of L-Arginine
July 23, 2021
Arginine is a popular sports supplement, but could it also be useful in the context of healthy longevity? What is arginine? Arginine, also known as L-arginine, is an amino acid, a building block used to make proteins, that plays an important role in regulating blood flow.
Teasing Apart the Effects of Aging and COVID-19
July 22, 2021
Researchers have used a big data approach to disentangle cellular and physiological changes that are specific to COVID-19 from those caused by aging [1]. Identifying these improves our understanding of the disease and may help explain why COVID-19 has a more severe effect on older people.
Senescent Cells, p65, and a Possible Treatment for Cancer
July 21, 2021
A report in the Journal of Cell Science has outlined different stages of cellular senescence alongside a mechanism that reverses it, along with a potential new treatment for glioblastoma. Old paradigms in cellular senescence Cellular senescence contributes to aging and age-related diseases, likely primarily through the
Enriched Environments Youthen the Brains of Mice
July 20, 2021
A study published in Nature Communications has shown that an environment rich in stimuli changes the epigenetics of the mouse hippocampus, making the brains of aged mice more like those of young mice [1]. What is an enriched environment? For mice, enriched environments (ENRs) are “large
HDAC Inhibitors Linked to Cellular Senescence
July 19, 2021
A study published in Aging has shown that inhibiting histone deacetylases (HDACs), an approach used for treating cancer and other diseases, can lead to cellular senescence. What is a histone, anyway? In biology, a histone is a protein that binds to DNA in order to control
PulseChain Airdrop Raises $20m for SENS
July 17, 2021
The SENS Research Foundation has apparently already raised four times its annual income thanks to the PulseChain Airdrop. The PulseChain airdrop supporting aging research Richard Heart, the founder of HEX, is about to launch a new cryptocurrency called PulseChain. As part of that launch, he has
Loss of Peptide Not Amyloid Plaques a New Alzheimer’s Target
July 16, 2021
A recent study, led by the University of Cincinnati in collaboration with the Karolinska Institute in Sweden, challenges the popular amyloid hypothesis that has dominated Alzheimer’s research for decades. Amyloid accumulation may be the consequence, not the cause Over 100 years ago, Alois Alzheimer originally identified
Engineering Cells to Avoid Immune Detection in Transplants
July 15, 2021
Gene editing can make stem cells invisible to the immune system, making it possible to carry out cell therapy transplants without suppressing the patients’ immune response [1]. Help me help you Cellular therapies involve transplanting cells into a patient to replace the activity of malfunctioning or
The Enormous Economic Benefits of Targeting Aging
July 14, 2021
Using Peter Pan, Wolverine, and a powerful economic model, a trio of prominent scientists argues that slowing aging can bring gargantuan economic benefits – an order of magnitude bigger than previously thought [1]. The marriage of economics and geroscience The paper, published in Nature Aging, looks
NMN Enhances Aerobic Capacity in Amateur Runners
July 14, 2021
A clinical trial of endurance runners recently published in the Journal of the International Society of Sports Nutrition found nicotinamide mononucleotide (NMN) to increase several measures of aerobic capacity. Could NMN and exercise be synergistic? NMN is a NAD+ precursor well known to longevity researchers for
Telomere Loss And The Development Of Fibrosis
July 13, 2021
A new study published in Aging has shown a link between a reduction in telomerase reverse transcriptase (TERT), the gene that allows for telomere maintenance, and the development of myofibroblasts, cells that are a part of organ fibrosis. It also documents the link between telomere attrition
Senolytics Improve Spinal Cord Recovery in Mice
July 12, 2021
A new study published in Cell Reports has shown that the senolytic navitoclax (ABT-263) helps mice heal from spinal cord injuries [1]. The difference between mice and zebrafish The zebrafish is a well-known species studied for its regenerative abilities, so the researchers began their investigation by
Senolytics Show Positive Results in Phase 1 Clinical Trial
July 9, 2021
Leading the pack is never easy, but today, UNITY Biotechnology is back with some positive news for senolytics. Being first is not always easy UNITY Biotechnology is a company that has been developing senolytics for the removal of senescent cells, which accumulate with age, drive chronic
Castration Lengthens Lifespan of Sheep by Altering Androgens
July 8, 2021
Researchers have shown that castration makes male sheep live longer, and they’ve also used genomic data to get a basic understanding of the mechanism behind this longevity [1]. While castration is unlikely to be part of a life extension therapy, unraveling its effect on lifespan will
Niacin Tested Against Parkinson’s Disease
July 7, 2021
A clinical trial on the effectiveness of niacin supplementation in Parkinson’s disease patients has recently been published in Frontiers in Aging Neuroscience. The link between niacin and Parkinson’s disease Niacin is a form of vitamin B3 that is commonly manufactured as a dietary supplement. Patients with