Category: Biology of Aging
Some Brain Changes May Cause Strength Loss
June 17, 2024
In Aging Cell, researchers have published data on a causal link between brain structure changes and age-related muscle loss (sarcopenia). Not just falls and frailty Sarcopenia is a key reason
Treating Genetic Liver Diseases at Their Root
June 13, 2024
Researchers publishing in Cell Stem Cell have demonstrated that genetically diseased liver cells can be taken from human beings, altered in the laboratory, and used to regrow the livers of
A Natural Compound as an Osteoporosis Treatment
June 12, 2024
A team of researchers has found that corylin, a compound previously investigated for its anti-senesence properties, is effective against osteoporosis in a mouse model. A return to a well-known compound
How to Defeat Aging? Two Scientists Offer Their Visions
June 7, 2024
In a much-anticipated debate, prominent aging researchers Aubrey de Grey and Peter Fedichev presented their competing, but also overlapping, theories. Gentlemen, draw your laser pointers! When the non-profits Foresight Institute,
A New Approach to NAD+ in Sarcopenia
June 6, 2024
Researchers have published a potential new method of treating the age-related muscle loss known as sarcopenia in Aging Cell. A return to NAD+ We have previously published information relating to
Oral Microbiome Associated with Cognitive Performance
June 5, 2024
An analysis of oral microbes in older adults has indicated an association between microbial diversity and executive function performance [1]. Multiple factors impact cognitive impairment risk Aging is one of
Estrogen Metabolite Robustly Increases Lifespan in Male Mice
June 4, 2024
In the newest study by the Interventions Testing Program, 16α-hydroxyestriol and canagliflozin significantly increased lifespan in male mice but were deleterious for females [1]. The golden standard The Interventions Testing
Inhibiting a Transporter to Stop Senescence
June 3, 2024
Researchers publishing in Nature Aging have discovered that inhibiting a glucose transporter leads to a decrease in senescent cells. Forcing a reduction in calories This paper begins with a discussion
Study Suggests a Link Between Tattoos and Lymphoma
May 31, 2024
Scientists have reported a possible correlation between having tattoos and getting lymphoma later in life. However, multiple caveats apply [1]. Looks cool, but what about safety? Tattoos are a popular
An Animal Without an Observed Mortality Increase
May 30, 2024
The researchers of a previous controversial paper on the naked mole-rat’s impressive longevity have returned, publishing data in GeroScience that bolsters their original findings. A darling of longevity The naked
Air Pollution Is Associated with Dementia Risk
May 29, 2024
A long-term female nurse study suggests a link between long-term exposure to certain air pollutants, but not road traffic noise, and the risk of developing dementia [1]. Air pollution as
Ketogenic Diets Cause Cellular Senescence in Mice
May 28, 2024
A new study tested two ketogenic diets and found increases in cellular senescence in multiple tissues [1]. It’s complicated Ketogenic diets have been a matter of substantial debate. On one
Interrupting the Chain of Disc Degeneration
May 27, 2024
In Aging Cell, researchers have published a potential method of ameliorating disc degeneration that focuses on the cells living in a low-oxygen environment within the discs. Living on low oxygen
Why One Antioxidant Might Alleviate Disc Degeneration
May 26, 2024
In Aging Cell, researchers have published detailed information on why the antioxidant pyrroloquinoline quinone (PQQ), which is known to be safe in humans, alleviates age-related disc degeneration in mice. A
Investigating Why Brain Plasticity Decreases with Age
May 23, 2024
Publishing in Aging, a team of researchers has used a rat model to investigate a possible reason why old people are less able to learn new things. A critical receptor
Some Brain Changes May Cause Strength Loss
June 17, 2024
In Aging Cell, researchers have published data on a causal link between brain structure changes and age-related muscle loss (sarcopenia). Not just falls and frailty Sarcopenia is a key reason for the loss of independence among older people. Data on the prevalence of this gradual disorder
Treating Genetic Liver Diseases at Their Root
June 13, 2024
Researchers publishing in Cell Stem Cell have demonstrated that genetically diseased liver cells can be taken from human beings, altered in the laboratory, and used to regrow the livers of model mice. Recreating an entire organ has its own difficulties These researchers begin their paper by
A Natural Compound as an Osteoporosis Treatment
June 12, 2024
A team of researchers has found that corylin, a compound previously investigated for its anti-senesence properties, is effective against osteoporosis in a mouse model. A return to a well-known compound Corylin is a compound that was first discovered in Psoralea corylifolia, a plant commonly used in
How to Defeat Aging? Two Scientists Offer Their Visions
June 7, 2024
In a much-anticipated debate, prominent aging researchers Aubrey de Grey and Peter Fedichev presented their competing, but also overlapping, theories. Gentlemen, draw your laser pointers! When the non-profits Foresight Institute, Open Longevity, and Say Forever had the idea to hold debates on the best strategy to
A New Approach to NAD+ in Sarcopenia
June 6, 2024
Researchers have published a potential new method of treating the age-related muscle loss known as sarcopenia in Aging Cell. A return to NAD+ We have previously published information relating to exercise and NAD+ levels, and previous work has investigated the relationship between NAD+ and sarcopenia, the
Oral Microbiome Associated with Cognitive Performance
June 5, 2024
An analysis of oral microbes in older adults has indicated an association between microbial diversity and executive function performance [1]. Multiple factors impact cognitive impairment risk Aging is one of the major risk factors for cognitive impairment and dementia, but it is not the only one.
Estrogen Metabolite Robustly Increases Lifespan in Male Mice
June 4, 2024
In the newest study by the Interventions Testing Program, 16α-hydroxyestriol and canagliflozin significantly increased lifespan in male mice but were deleterious for females [1]. The golden standard The Interventions Testing Program, now entering its 20th year, is a monumental undertaking by the National Institute on Aging
Inhibiting a Transporter to Stop Senescence
June 3, 2024
Researchers publishing in Nature Aging have discovered that inhibiting a glucose transporter leads to a decrease in senescent cells. Forcing a reduction in calories This paper begins with a discussion of the well-known problems with widespread cellular senescence and its connections with other aspects of aging.
Study Suggests a Link Between Tattoos and Lymphoma
May 31, 2024
Scientists have reported a possible correlation between having tattoos and getting lymphoma later in life. However, multiple caveats apply [1]. Looks cool, but what about safety? Tattoos are a popular form of self-expression, and in recent years, they are becoming more prevalent, probably due to the
An Animal Without an Observed Mortality Increase
May 30, 2024
The researchers of a previous controversial paper on the naked mole-rat’s impressive longevity have returned, publishing data in GeroScience that bolsters their original findings. A darling of longevity The naked mole-rat, an unusually long-lived rodent species that lives in large colonies, has long been a mystery
Air Pollution Is Associated with Dementia Risk
May 29, 2024
A long-term female nurse study suggests a link between long-term exposure to certain air pollutants, but not road traffic noise, and the risk of developing dementia [1]. Air pollution as a risk factor Air pollution is a known risk factor for many conditions, such as cardiovascular
Ketogenic Diets Cause Cellular Senescence in Mice
May 28, 2024
A new study tested two ketogenic diets and found increases in cellular senescence in multiple tissues [1]. It’s complicated Ketogenic diets have been a matter of substantial debate. On one hand, they are effective against childhood epilepsy [2], have shown some promise against neurodegeneration [3] and
Interrupting the Chain of Disc Degeneration
May 27, 2024
In Aging Cell, researchers have published a potential method of ameliorating disc degeneration that focuses on the cells living in a low-oxygen environment within the discs. Living on low oxygen Yesterday, we discussed how an antioxidant compound was found to alleviate intervertebral disk degeneration (IVDD). This
Why One Antioxidant Might Alleviate Disc Degeneration
May 26, 2024
In Aging Cell, researchers have published detailed information on why the antioxidant pyrroloquinoline quinone (PQQ), which is known to be safe in humans, alleviates age-related disc degeneration in mice. A return to antioxidants Oxidative stress was once considered to be the core of aging, a concept
Investigating Why Brain Plasticity Decreases with Age
May 23, 2024
Publishing in Aging, a team of researchers has used a rat model to investigate a possible reason why old people are less able to learn new things. A critical receptor This paper begins with a discussion of receptors for N-methyl-D-aspartate (NMDA), a compound that affects multiple