Category: Research
Reversing Cellular Age in Mice Restores Vision
December 4, 2020
Researchers at the Sinclair Lab at Harvard Medical School have restored lost vision to old mice, and mice with damaged retinal nerves, using partial cellular reprogramming. The aged cells can
A New Biomaterial for Thymic Cells
December 3, 2020
New research published in Biomacromolecules has successfully cultured thymic epithelial cells in vitro. A 3D biomaterial for thymic epithelial cells Tissue engineering and regenerative medicine attempts to regenerate tissues both
A Key Gene Links Diet and Longevity
December 3, 2020
A key gene mediating the effect of dietary restriction on longevity has been identified, improving our understanding of the link between the two and raising the prospect of more targeted
Neurological Aging and the Lifespan Limit
December 2, 2020
Jeanne Louise Calment from France was the oldest person to grace this Earth, living a full life until 122 years of age [1]. She continuously exercised, taking up fencing in
CRISPR Successfully Deployed Against Two Cancer Types
December 2, 2020
Scientists have successfully tested a new nanoparticle-based delivery system for CRISPR kits, achieving drastic improvements in mouse models of glioblastoma and ovarian cancer [1]. A gift from our single-cell ancestors
Resveratrol Human Trial Results Published
November 30, 2020
A human study on the popular supplement resveratrol on heart failure patients has been published, and the results are significant. What is resveratrol? Resveratrol, is a naturally occurring stilbenoid, a
Linking Alzheimer’s Disease and Gut Bacteria
November 27, 2020
In recent years, there has been evidence that the gut microbiota plays an important role in the development of Alzheimer’s disease. Certainly, there is evidence that there is a bacterial
GrimAge Is the Best Clock for Predicting Death
November 26, 2020
A new study published in the Journals of Gerontology has shown that the epigenetic clock GrimAge is a strong predictor of the effects of aging, particularly all-cause mortality: the likelihood
Immune Protection for Insulin-Producing Cells
November 25, 2020
Recent research published in Nature Biomedical Engineering has shown a way to dramatically improve the feasibility of transplanting therapeutic cells, particularly pancreatic islet cells, while protecting them from the recipient’s
Gene Discovered to Alleviate Obesity
November 24, 2020
Researchers have discovered a chemical pathway that alleviates many harmful consequences of obesity while having little effect on obesity itself [1]. Obesity is bad for your lifespan. This is one
Media Circus Surrounds Hyperbaric Oxygen Study
November 23, 2020
If you have been following the mainstream media recently, you have probably seen a story about hyperbaric oxygen treatment and claims that it can reverse aging. Unfortunately, the media hype
A New Scaffold for Liver Regeneration
November 20, 2020
A new scaffold for liver regeneration has been characterized and published in the International Journal of Biological Macromolecules this week. A need for transplants Because of the early onset of
Avoiding Osteoporosis with Alpha-Ketoglutarate
November 19, 2020
Research on rodents shows that alpha-ketoglutarate could be an effective way to treat or even prevent osteoporosis [1]. Feeling frail Osteoporosis increases the risk of bone fractures in older people,
Inflammation Decreases NAD+ During Aging
November 18, 2020
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in all living cells and is essential for cells to work; without it, life would be impossible. The connection between aging and
Diluting Aged Blood Rejuvenates Old Brains
November 17, 2020
There has been a great deal of interest in the last few years in the potential regenerative properties of blood factors. This has led to two broad schools of thought:
Reversing Cellular Age in Mice Restores Vision
December 4, 2020
Researchers at the Sinclair Lab at Harvard Medical School have restored lost vision to old mice, and mice with damaged retinal nerves, using partial cellular reprogramming. The aged cells can be reset to become younger again using this approach and are better at repairing damaged tissue.
A New Biomaterial for Thymic Cells
December 3, 2020
New research published in Biomacromolecules has successfully cultured thymic epithelial cells in vitro. A 3D biomaterial for thymic epithelial cells Tissue engineering and regenerative medicine attempts to regenerate tissues both in the lab and in vivo. While the fact that everyone experiences thymic involution should make
A Key Gene Links Diet and Longevity
December 3, 2020
A key gene mediating the effect of dietary restriction on longevity has been identified, improving our understanding of the link between the two and raising the prospect of more targeted therapeutic interventions. Less is more Dietary restriction is one of the most reliable ways to increase
Neurological Aging and the Lifespan Limit
December 2, 2020
Jeanne Louise Calment from France was the oldest person to grace this Earth, living a full life until 122 years of age [1]. She continuously exercised, taking up fencing in her 80s and cycling in her 100s. She claimed to have achieved such a long life
CRISPR Successfully Deployed Against Two Cancer Types
December 2, 2020
Scientists have successfully tested a new nanoparticle-based delivery system for CRISPR kits, achieving drastic improvements in mouse models of glioblastoma and ovarian cancer [1]. A gift from our single-cell ancestors CRISPR gene editing technology has been widely hailed as a potential game changer in medicine, including
Resveratrol Human Trial Results Published
November 30, 2020
A human study on the popular supplement resveratrol on heart failure patients has been published, and the results are significant. What is resveratrol? Resveratrol, is a naturally occurring stilbenoid, a type of phenol that is present in various plants and foods, such as grapes, peanuts, cocoa,
Linking Alzheimer’s Disease and Gut Bacteria
November 27, 2020
In recent years, there has been evidence that the gut microbiota plays an important role in the development of Alzheimer’s disease. Certainly, there is evidence that there is a bacterial element in some cases of Alzheimer’s disease, and a new study further reinforces this link. The
GrimAge Is the Best Clock for Predicting Death
November 26, 2020
A new study published in the Journals of Gerontology has shown that the epigenetic clock GrimAge is a strong predictor of the effects of aging, particularly all-cause mortality: the likelihood of dying from any cause. Did previous clocks use the wrong target? As the researchers explain,
Immune Protection for Insulin-Producing Cells
November 25, 2020
Recent research published in Nature Biomedical Engineering has shown a way to dramatically improve the feasibility of transplanting therapeutic cells, particularly pancreatic islet cells, while protecting them from the recipient’s immune response. Shielding transplanted cells from the immune system Because the functions of the pancreas are
Gene Discovered to Alleviate Obesity
November 24, 2020
Researchers have discovered a chemical pathway that alleviates many harmful consequences of obesity while having little effect on obesity itself [1]. Obesity is bad for your lifespan. This is one of the fundamental truths of longevity science. Obesity drastically increases our susceptibility to cardiovascular diseases, type
Media Circus Surrounds Hyperbaric Oxygen Study
November 23, 2020
If you have been following the mainstream media recently, you have probably seen a story about hyperbaric oxygen treatment and claims that it can reverse aging. Unfortunately, the media hype surrounding the results is nothing like the reality of the actual research paper, and this is
A New Scaffold for Liver Regeneration
November 20, 2020
A new scaffold for liver regeneration has been characterized and published in the International Journal of Biological Macromolecules this week. A need for transplants Because of the early onset of many liver diseases relative to most age-related diseases, liver transplantations have the ability to dramatically extend
Avoiding Osteoporosis with Alpha-Ketoglutarate
November 19, 2020
Research on rodents shows that alpha-ketoglutarate could be an effective way to treat or even prevent osteoporosis [1]. Feeling frail Osteoporosis increases the risk of bone fractures in older people, harming them as individuals and increasing the load on hospitals as the average age of the
Inflammation Decreases NAD+ During Aging
November 18, 2020
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in all living cells and is essential for cells to work; without it, life would be impossible. The connection between aging and the accompanying loss of NAD+ has been the subject of much research, and a new study
Diluting Aged Blood Rejuvenates Old Brains
November 17, 2020
There has been a great deal of interest in the last few years in the potential regenerative properties of blood factors. This has led to two broad schools of thought: one in which there are regenerative factors in young blood that can be isolated, and another