Category: Research
Aged Blood Makes Young Cells Old
November 12, 2020
A team of researchers, including Dr. Tony Wyss-Coray, co-founder of Alkahest, has discovered that exposing young cells to aged blood makes their gene expression like old cells. Signaling cells to
Researchers Use Lung Organoids to Study COVID
November 11, 2020
Using a novel 3D lung organoid model, new research published in Cell Stem Cell has shed light on the body’s infection response to COVID-19. Generating lung tissue in vitro Lung
AI and Longevity Meet in a New Book
November 10, 2020
Artificial intelligence is the next big thing in medicine, or, using Silicon Valley’s jargon, the next big disruptor. Not a thing of the future, AI is already here, changing our
OneSkin Has Released a Senotherapeutic Skin Cream
November 9, 2020
If there is one thing about aging research that is almost sure to grab public attention, it is something that has a visible effect. A new product on the market
The Extracellular Matrix Is Key to Heart Health
November 4, 2020
A new article published by the International Journal of Molecular Sciences sheds light on the differences between the extracellular matrix (ECM) of healthy people and people in end-stage heart failure.
Metformin and Resistance Training: Downside and Upside
October 29, 2020
A new study published in Aging has shown that although taking metformin while undergoing resistance training limits muscle growth, it promotes youthful gene expression. The downside As the researchers of
Cartilage Regeneration Accomplished in Vitro
October 28, 2020
New research published in Stem Cell Research and Therapy has improved the regenerative potential of chondrocytes in vitro. The challenges of cartilage regeneration Regenerative medicine strategies aim to regenerate the
Breanna Deutsch Explains How to Find the Fountain
October 27, 2020
Aging research is still an emerging field, and its emergence has been laden with difficulties. Until recently, the budgets were scarce, the ideas ridiculed, and public involvement nonexistent. The tide
Partial Cellular Reprogramming Improves Memory in Old Mice
October 26, 2020
Today, we want to highlight another study that takes us a step closer to getting partial cellular reprogramming to the clinic. Can we both have our cake and eat it?
A Genetic Footprint of Aging
October 22, 2020
A new analysis has revealed a core set of genes involved in aging in both humans and mice. Together with a broader set of age-related genes assembled by the study
Generating Neural Progenitor Cells from iPSCs
October 21, 2020
The latest research published in the Journal of Tissue Engineering and Regenerative Medicine has reprogrammed pig fibroblast cells into neural progenitor cells.
A New Mechanism of Telomere Lengthening in T Cells Discovered
October 20, 2020
An international collective of scientists has discovered a new cellular process: telomere transfer from antigen-presenting cells to T cells that boosts the latter’s lifespan and proliferative potential [1]. T cells,
Using CRISPR to Remove Mutated DNA to Defeat Cancer
October 19, 2020
Researchers have successfully used the CRISPR/Cas9 gene editing tool to destroy Ewing’s sarcoma and chronic myeloid leukemia tumor cells by targeting the fusion genes responsible for these tumors [1]. Fusion
Insilico Partners with Taisho for Senolytic Drug Discovery
October 16, 2020
Insilico Medicine has announced a historic deal with the Taisho Pharmaceutical Company, which is based in Japan, in a partnership to identify and develop new senolytic drugs. The companies have
Uncovering the Origin of the SASP
October 15, 2020
A new study published in Nature shows a strong link between the protein G3BP1 and the SASP, a harmful byproduct of senescent cells.
Aged Blood Makes Young Cells Old
November 12, 2020
A team of researchers, including Dr. Tony Wyss-Coray, co-founder of Alkahest, has discovered that exposing young cells to aged blood makes their gene expression like old cells. Signaling cells to act older We have known from the heterochronic parabiosis and plasmapheresis research performed by Dr. Irina
Researchers Use Lung Organoids to Study COVID
November 11, 2020
Using a novel 3D lung organoid model, new research published in Cell Stem Cell has shed light on the body’s infection response to COVID-19. Generating lung tissue in vitro Lung tissue regeneration is an elusive scientific goal that would have a major implications for treating patients
AI and Longevity Meet in a New Book
November 10, 2020
Artificial intelligence is the next big thing in medicine, or, using Silicon Valley’s jargon, the next big disruptor. Not a thing of the future, AI is already here, changing our lives, and soon our healthcare, beyond recognition. Given how rapidly AI is invading the field of
OneSkin Has Released a Senotherapeutic Skin Cream
November 9, 2020
If there is one thing about aging research that is almost sure to grab public attention, it is something that has a visible effect. A new product on the market that claims to reduce senescent cells in aged skin could achieve that, assuming that the pending
The Extracellular Matrix Is Key to Heart Health
November 4, 2020
A new article published by the International Journal of Molecular Sciences sheds light on the differences between the extracellular matrix (ECM) of healthy people and people in end-stage heart failure. The key to the heart could be its ECM Regeneration of heart tissue following a heart
Metformin and Resistance Training: Downside and Upside
October 29, 2020
A new study published in Aging has shown that although taking metformin while undergoing resistance training limits muscle growth, it promotes youthful gene expression. The downside As the researchers of this study point out, previous research shows that taking metformin while undergoing physical resistance training (PRT)
Cartilage Regeneration Accomplished in Vitro
October 28, 2020
New research published in Stem Cell Research and Therapy has improved the regenerative potential of chondrocytes in vitro. The challenges of cartilage regeneration Regenerative medicine strategies aim to regenerate the natural cartilage itself to its former glory. This can be either by kick-starting the body’s own
Breanna Deutsch Explains How to Find the Fountain
October 27, 2020
Aging research is still an emerging field, and its emergence has been laden with difficulties. Until recently, the budgets were scarce, the ideas ridiculed, and public involvement nonexistent. The tide is turning, with more private and institutional players eager to spend money and effort on the
Partial Cellular Reprogramming Improves Memory in Old Mice
October 26, 2020
Today, we want to highlight another study that takes us a step closer to getting partial cellular reprogramming to the clinic. Can we both have our cake and eat it? As previous studies [1] have taught us, partial cellular reprogramming is a balancing act of epigenetically
A Genetic Footprint of Aging
October 22, 2020
A new analysis has revealed a core set of genes involved in aging in both humans and mice. Together with a broader set of age-related genes assembled by the study [1], this resource will serve as a launching point for further investigations of the mechanisms behind
Generating Neural Progenitor Cells from iPSCs
October 21, 2020
The latest research published in the Journal of Tissue Engineering and Regenerative Medicine has reprogrammed pig fibroblast cells into neural progenitor cells.
A New Mechanism of Telomere Lengthening in T Cells Discovered
October 20, 2020
An international collective of scientists has discovered a new cellular process: telomere transfer from antigen-presenting cells to T cells that boosts the latter’s lifespan and proliferative potential [1]. T cells, an important element of our adaptive immune system, are born as non-proliferating cells and, as such,
Using CRISPR to Remove Mutated DNA to Defeat Cancer
October 19, 2020
Researchers have successfully used the CRISPR/Cas9 gene editing tool to destroy Ewing’s sarcoma and chronic myeloid leukemia tumor cells by targeting the fusion genes responsible for these tumors [1]. Fusion genes, a feature in many different types of cancer, arise when a mutation fuses two genes
Insilico Partners with Taisho for Senolytic Drug Discovery
October 16, 2020
Insilico Medicine has announced a historic deal with the Taisho Pharmaceutical Company, which is based in Japan, in a partnership to identify and develop new senolytic drugs. The companies have agreed to collaborate on AI-powered drug discovery focused on identifying molecules to remove problematic senescent cells.
Uncovering the Origin of the SASP
October 15, 2020
A new study published in Nature shows a strong link between the protein G3BP1 and the SASP, a harmful byproduct of senescent cells.