October 16, 2026
A new study links STING-mediated signals from marrow fat cells to inflammation and declining NAD⁺ levels in bone-forming cells. Interrupting this pathway helped preserve aging bone [1]. Making old bones Our bones live a complex life, as they are constantly remodeled: cells called osteoclasts break down existing bone, while osteoblasts build new bone. Osteoblasts arise...
June 08, 2023
Scientists have verified the effectiveness of stem cell transplants, researched a core reason behind it, and published their findings in Aging Cell. The niche controls what stem cells do Back in 1978, Raymond Schofield proposed that hematopoietic stem cells (HSCs), which make blood cells, are governed by their local microenvironment, the niche in which they...
May 06, 2019
Stem cell transplants have been of great interest to aging researchers, and, in a new study, they have successfully increased mouse lifespan by using stem cell therapy. While this has been previously achieved, this experiment was more refined than older studies and sheds new light on the potential of tissue regeneration through stem cells. The...