May 14, 2026
Most cardiovascular trials focus on lowering LDL cholesterol or reducing inflammation to slow disease progression. UDP-003 targets the root cause: toxic 7-ketocholesterol (7KC) inside macrophages and soft plaques. It is designed to convert bloated foam cells back into healthy macrophages that can actively clear the hard plaque. This clinical trial took place at CMAX, a...
September 10, 2021
Underdog Pharmaceuticals (Now called Cyclarity Therapeautics) has just issued a press release announcing that UDP-003, a compound being studied for its effectiveness against oxidized cholesterol, has been given an Innovation Passport under the UK's Innovative Licensing and Access Pathway program. This is similar to the Fast Track designation given by the FDA in the United...