Category: News

Rat in maze

Testosterone Restores Brain Function in Old Male Rats

Researchers from Hebei Medical University in China have found that testosterone supplementation ameliorates age-related brain dysfunction in male rats. A focus on mitochondria Previous research has shown that testosterone supplementation

Time restricted eating

Caloric Restriction Attenuates Immunosenescence

Scientists have shown in mice that long-term caloric restriction can attenuate age-related immunosenescence on par with antibody-mediated clearance of senescent T-cells. On top of that, caloric restriction predictably improved glucose

Rejuvenation Roundup June

Rejuvenation Roundup June 2021

This month, there’s been plenty of exciting news in the world of research and development, and there’s good news about our recently completed crowdfunding campaign and upcoming conference. Here’s what’s

Unexpected treasure

Life Extension Drug Discovered by Accident

Researchers have found that zoledronate, a drug used to treat osteoporosis, has unexpected life-extending properties in human beings, and they confirmed these findings in a fruit fly study. The original

Neuropathy

Intellia Shows CRISPR Gene Editing in Humans Has Arrived

Intellia has released clinical data for NTLA-2001, a gene therapy for hereditary transthyretin amyloidosis. What is transthyretin amyloidosis? Transthyretin (ATTR) amyloidosis is the buildup of misfolded transthyretin, a protein generated

Journal Club

Rapamycin Improves DNA Storage

Journal Club returns on June 29th at noon Eastern Time with Dr. Oliver Medvedik. This month we are taking a look at rapamycin, a drug that has long been believed

Quantum computer

Can Quantum Computing Help Discover New Drugs?

With a new announcement from IBM and Germany’s Fraunhofer Institute, the era of quantum computing has finally arrived in Europe. Can its advance speed up the discovery of new drugs?

What is Niacin? A Summary of Nicotinic Acid

Niacin is a common dietary supplement with a long research history and more than a few tricks up its sleeve. Recent human trials have shed new light on its possible role in addressing mitochondrial dysfunction and aging. What is niacin? Niacin is a form of water-soluble

Rat in maze

Testosterone Restores Brain Function in Old Male Rats

Researchers from Hebei Medical University in China have found that testosterone supplementation ameliorates age-related brain dysfunction in male rats. A focus on mitochondria Previous research has shown that testosterone supplementation helps offset some of the symptoms of Alzheimer’s disease [1] and Parkinson’s disease [2] in men.

Ginseng

Ginseng Compound Reduces Senescent Marker in Humans

A study conducted by researchers at the University of Taipei in Taiwan has shown that the ginseng derivative Rg1 decreases the cellular senescence marker p16INK4a in fitness-trained men 24 hours after exercise. An experiment to link p16INK4a, aging, exercise, and Rg1 The cell cycle inhibitor p16INK4a,

Time restricted eating

Caloric Restriction Attenuates Immunosenescence

Scientists have shown in mice that long-term caloric restriction can attenuate age-related immunosenescence on par with antibody-mediated clearance of senescent T-cells. On top of that, caloric restriction predictably improved glucose tolerance and lowered inflammation [1]. Senescent cells: inflamed and half-dead Immunosenescence is an umbrella term for

Gut bacteria

Gut Bacteria Strongly Influence the Aging Genome in Flies

Most of the genetic changes associated with increasing age disappear in the absence of gut bacteria, according to a new fruit fly study [1]. It’s a pretty surprising finding, and while there are some important implications, it’s also a bit challenging to interpret. A flat aging

Rejuvenation Roundup June

Rejuvenation Roundup June 2021

This month, there’s been plenty of exciting news in the world of research and development, and there’s good news about our recently completed crowdfunding campaign and upcoming conference. Here’s what’s happened in the month of June. LEAF News PEARL Is Funded, Rapamycin Longevity Clinical Trials Begin:

Unexpected treasure

Life Extension Drug Discovered by Accident

Researchers have found that zoledronate, a drug used to treat osteoporosis, has unexpected life-extending properties in human beings, and they confirmed these findings in a fruit fly study. The original unexpected findings Zoledronate is a biophosphonate, a drug used to strengthen bones and reduce the risk

Nir Barzilai Interview about metformin and longevity.

Dr. Nir Barzilai: “We Can Live Healthier for Longer”

Dr. Nir Barzilai is one of the leading experts in geroscience, with more than 25 years of longevity research under his belt. He is the director of the Institute for Aging Research at the Albert Einstein College of Medicine and the author of the book Age

Neuropathy

Intellia Shows CRISPR Gene Editing in Humans Has Arrived

Intellia has released clinical data for NTLA-2001, a gene therapy for hereditary transthyretin amyloidosis. What is transthyretin amyloidosis? Transthyretin (ATTR) amyloidosis is the buildup of misfolded transthyretin, a protein generated by the liver. Normally, this protein is partially responsible for the transport of thyroid hormones, hence

Grey Hair

Grey Hair Can Change Back to Original Color

Many people dread finding their first greying hairs, which is often their first sign that aging is creeping up on them and that the fire of youth is starting to die down and smolder. To some readers, greying hair may seem to be a superficial issue;

Lifespan Docs Save the Animals

300 Years of Saving Animals, a Wildlife Guardian’s Wish

Today, we are proud to announce the second video in our Lifespan Docs series. This is part of an ongoing series of videos that focuses on the positive aspects of a world in which healthy life extension is possible. As part of that, we are making

Pulling backwards

Evolution Won’t Stop Aging Any Time Soon, but Medicine Might

A new study [1] about the ‘invariant rate of ageing’ has led to reports that aging is unstoppable and that we cannot cheat death. However, this reporting is based on a misunderstanding of what the study actually says. The misinterpretations The study shows that “immortality and

Stem cell development

How Stem Cells Promote the Health of Nearby Cells

A new study published in the FASEB Journal shows how mesenchymal stem cells derived from adipose tissue (ADSCs) reverse some effects of aging in nearby cells. It’s not the cells themselves, it’s what they secrete The original and ongoing main purpose of stem cell therapies is

Journal Club

Rapamycin Improves DNA Storage

Journal Club returns on June 29th at noon Eastern Time with Dr. Oliver Medvedik. This month we are taking a look at rapamycin, a drug that has long been believed to slow down aging, and how it changes the way DNA is stored inside cells to

Quantum computer

Can Quantum Computing Help Discover New Drugs?

With a new announcement from IBM and Germany’s Fraunhofer Institute, the era of quantum computing has finally arrived in Europe. Can its advance speed up the discovery of new drugs? Europe joins the race Despite being a research and manufacturing powerhouse, Germany, like Europe as a