Category: News
Fecal Transplantation for Alzheimer’s Disease
September 7, 2021
A recent review published in Cureus shows why fecal microbial transplantation (FMT) might be able to help sufferers of Alzheimer’s disease, showing how tightly the gut and brain are intertwined.
Altos Labs Launches with a Focus on Cellular Reprogramming
September 6, 2021
A new company focused on aging has launched, and it has the backing of Yuri Milner and Jeff Bezos among other wealthy people interested in tackling aging. Altos Labs is
A Peptide Boosts Cognition in Mouse Study
September 3, 2021
Cognitive decline and neurological aging may involve a peptide known as adropin, according to new research. The identification of this link offers a new perspective on the aging brain and
Exploring the Senescence-Associated Secretory Phenotype
September 2, 2021
Today, we want to highlight a recent review that charts the pro-inflammatory signals produced by senescent cells [1]. What is the senescence-associated secretory phenotype? As we grow older, an increasing
Fasting May Be Beneficial For Human Longevity
September 1, 2021
A recent study in Clinical and Translational Medicine followed people who went 5 days without eating and found improvements both immediately afterwards and up to 98 days later. Fasting for
Rejuvenation Roundup August 2021
September 1, 2021
August is over, and with it, our annual Ending Age-Related Diseases conference! EARD2021 was a great success, and we would like to thank our attendees and sponsors for their support.
What are Senolytics? A Summary of Senotherapeutics
September 1, 2021
In this article we will take a look at senolytics and how they have the potential to reverse some aspects of the aging process. Senescent cells and aging As your
The Road Between Inflammation and Heart Aging
August 31, 2021
A team of Chinese researchers has outlined the cellular link between age-related inflammation (inflammaging) and the physical aging of heart muscle cells (cardiomyocytes). NLRP3 and why it matters We have
Early Antibiotic Exposure Can Decrease Lifespan in Mice
August 30, 2021
A study published in Cell Reports has shown that early-life exposure to antibiotics that destroy the gut flora can harm the lifelong development of mice, including lifespan. Three groups with
DunedinPACE – A Next Generation Epigenetic Aging Clock
August 27, 2021
With so many health and disease outcomes connected to the biological aging processes, research into quantifying and tracking aging has surged in recent years due to the work of Steve
What is Resveratrol? A Summary of Resveratrol
August 26, 2021
Probably best known for its presence in grapes and wine, this popular dietary supplement may have a few tricks up its sleeve. What is resveratrol? Resveratrol is a stilbenoid, a
Collagen, Senescence, and Age-Related Hair Loss
August 25, 2021
Last week, a new study published in Aging reported similar mechanisms of TGF-ß2 and collagen on hair follicle aging, dermal papilla cell senescence, and in vitro spheroid formation. Aging hair
Working the Deletion Problem out of CRISPR
August 24, 2021
In a study published in Genome Biology, researchers explain how they are working to make CRISPR less prone to large, accidental deletions of genetic material [1]. A previously unknown large
Stress, Sensory Gating, and Cognitive Decline With Age
August 23, 2021
Researchers publishing in Aging have found that stresses, both biological and in daily life, harm one of our fundamental abilities to correctly process what’s going on around us. What is
Longeveron Takes Aim at Aging with Cell Therapy
August 18, 2021
Longeveron has just announced the first data from its Phase 2b clinical trial that targets frailty with Lomecel-B, an MSC-based cell therapy. A longevity strategy built in More and more,
Fecal Transplantation for Alzheimer’s Disease
September 7, 2021
A recent review published in Cureus shows why fecal microbial transplantation (FMT) might be able to help sufferers of Alzheimer’s disease, showing how tightly the gut and brain are intertwined. Why would this ever work? The gut and brain are closely linked through biochemistry, and last
Altos Labs Launches with a Focus on Cellular Reprogramming
September 6, 2021
A new company focused on aging has launched, and it has the backing of Yuri Milner and Jeff Bezos among other wealthy people interested in tackling aging. Altos Labs is founded to treat aging itself In recent months, there have been some hints but considerable secrecy
A Peptide Boosts Cognition in Mouse Study
September 3, 2021
Cognitive decline and neurological aging may involve a peptide known as adropin, according to new research. The identification of this link offers a new perspective on the aging brain and points to novel potential therapies. A newly discovered metabolic neuropeptide The adropin protein is encoded by
Exploring the Senescence-Associated Secretory Phenotype
September 2, 2021
Today, we want to highlight a recent review that charts the pro-inflammatory signals produced by senescent cells [1]. What is the senescence-associated secretory phenotype? As we grow older, an increasing number of aged cells in our body enter a state called senescence. At this point, the
Fasting May Be Beneficial For Human Longevity
September 1, 2021
A recent study in Clinical and Translational Medicine followed people who went 5 days without eating and found improvements both immediately afterwards and up to 98 days later. Fasting for longevity Fasting is a practice in which an individual abstains from food and calories for a
Rejuvenation Roundup August 2021
September 1, 2021
August is over, and with it, our annual Ending Age-Related Diseases conference! EARD2021 was a great success, and we would like to thank our attendees and sponsors for their support. We will be releasing videos from this event over the coming months, so stay tuned. LEAF
What are Senolytics? A Summary of Senotherapeutics
September 1, 2021
In this article we will take a look at senolytics and how they have the potential to reverse some aspects of the aging process. Senescent cells and aging As your body ages, increasing amounts of your cells enter into a state of senescence. Senescent cells do
The Road Between Inflammation and Heart Aging
August 31, 2021
A team of Chinese researchers has outlined the cellular link between age-related inflammation (inflammaging) and the physical aging of heart muscle cells (cardiomyocytes). NLRP3 and why it matters We have previously discussed the NLRP3 inflammasome, which releases inflammatory cytokines upon exposure to irritants [1], including reactive
Early Antibiotic Exposure Can Decrease Lifespan in Mice
August 30, 2021
A study published in Cell Reports has shown that early-life exposure to antibiotics that destroy the gut flora can harm the lifelong development of mice, including lifespan. Three groups with different microbiota To begin the study, the researchers fed 20 baby mice, as well as their
DunedinPACE – A Next Generation Epigenetic Aging Clock
August 27, 2021
With so many health and disease outcomes connected to the biological aging processes, research into quantifying and tracking aging has surged in recent years due to the work of Steve Horvath, Morgan Levine, and others. Currently, epigenetic analysis of biological aging is thought to be the
What is Resveratrol? A Summary of Resveratrol
August 26, 2021
Probably best known for its presence in grapes and wine, this popular dietary supplement may have a few tricks up its sleeve. What is resveratrol? Resveratrol is a stilbenoid, a type of natural phenol. It is a phytoalexin, a growth-inhibiting substance created by plant tissues in
Collagen, Senescence, and Age-Related Hair Loss
August 25, 2021
Last week, a new study published in Aging reported similar mechanisms of TGF-ß2 and collagen on hair follicle aging, dermal papilla cell senescence, and in vitro spheroid formation. Aging hair follicles Hair follicles reside in the epidermal and dermal skin layers. At their base is the
Working the Deletion Problem out of CRISPR
August 24, 2021
In a study published in Genome Biology, researchers explain how they are working to make CRISPR less prone to large, accidental deletions of genetic material [1]. A previously unknown large problem While this seems counterintuitive, previous technology only allowed for the ready identification of deletions below
Stress, Sensory Gating, and Cognitive Decline With Age
August 23, 2021
Researchers publishing in Aging have found that stresses, both biological and in daily life, harm one of our fundamental abilities to correctly process what’s going on around us. What is sensory gating? Sensory gating is the brain’s ability to filter out irrelevant stimuli after the first
Longeveron Takes Aim at Aging with Cell Therapy
August 18, 2021
Longeveron has just announced the first data from its Phase 2b clinical trial that targets frailty with Lomecel-B, an MSC-based cell therapy. A longevity strategy built in More and more, biotech start-ups are applying longevity strategies to their therapeutic pipelines. Among them, Longeveron stands out as