Category: News
MSC Extracellular Vesicles Reduce Mouse Senescence
March 24, 2021
A new study in Aging Cell has shown extracellular vesicles from stem cells to extend healthspan and reduce cellular senescence in vitro and in mice. Stem cell exhaustion is a
Thyroid Organoids Created From Human Tissue
March 23, 2021
In a new study published in Stem Cell Reports, researchers have developed organoids to replace thyroid function [1]. If this approach is fully fleshed out and successfully brought to the
Human Trial Suggests Clearing Plaques Slows Mental Decline
March 22, 2021
Until now, it was unclear as to whether drugs that clear amyloid, which accumulate in the brain during aging and accompany diseases such as Alzheimer’s, have any influence over cognitive
A Summary of B Cells
March 22, 2021
The immune system as a whole can be broadly separated into two main branches: the innate immune response and the adaptive immune response. The innate immune response is performed by
Reduced Nicotinamide Mononucleotide Is a New NAD+ Precursor
March 19, 2021
There has been a lot of attention given to the NAD precursors nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR), sold as dietary supplements, to restore nicotinamide adenine dinucleotide (NAD) levels.
Broadening Longevity Research to Social Factors
March 18, 2021
The time has come for anti-aging research to incorporate behavioral and social science into its agenda, according to Terrie Moffitt, a psychology and neuroscience professor at Duke University [1]. She
Would Increased Longevity Be Boring?
March 17, 2021
Everlasting boredom is a common concern when it comes to the idea of extended human lifespans. There are many people who expect life to become empty and meaningless with time
Quantum Dot Nanomedicine for Longevity Drugs
March 17, 2021
New research in the journal ACS Nano describes a method to improve the efficiency of NMN and metformin in the liver by using a novel nanoparticle delivery method. Nanotechnology in
Major Health-Related Data Project Secures Funding in the UK
March 16, 2021
In the UK, the All-Party Parliamentary Group (APPG) for Longevity has secured funding for its Open Life Data project, which aims to create a framework for effective and ethical collection
We Celebrate Our Seventh Birthday!
March 15, 2021
Today, we celebrate our seventh birthday. On this very day, seven years ago, a group of healthy life extensionists decided to put their skin in the game and applied to
David Sinclair and Peter Attia Co-chair $200m Biotech SPAC
March 12, 2021
Another special purpose acquisition company (SPAC) focused on longevity and rejuvenation biotechnology has appeared recently, and with the addition of research rockstars David Sinclair and Peter Attia, it could mean
Managing Stress Responses to Slow Down Aging
March 11, 2021
Longevity research should better incorporate the effects of stress on aging, argues professor Elissa Epel of the University of California, San Francisco [1]. She proposes using the concept of stress
A Summary of NAD+ and Human Aging – Part 2
March 10, 2021
Welcome to part two of a two-part series exploring NAD+ biology; you can find part one here. There are already a myriad of excellent reviews on NAD+ biology in general
Longevity Pharmacology with Dr. João Pedro de Magalhães
March 10, 2021
Dr. João Pedro de Magalhães is a Professor at the University of Liverpool, England, where he studies aging and longevity at the genetic level, and he is also an affiliate
Binary Clock Predicts Biological Age
March 9, 2021
Scientists have devised a transcriptome-based aging clock that allows for precise measurement of biological age in C. elegans worms and shows promising results in humans as well [1]. The purpose
MSC Extracellular Vesicles Reduce Mouse Senescence
March 24, 2021
A new study in Aging Cell has shown extracellular vesicles from stem cells to extend healthspan and reduce cellular senescence in vitro and in mice. Stem cell exhaustion is a well-studied hallmark of aging that occurs in multiple model organisms and multiple tissue types in humans.
Thyroid Organoids Created From Human Tissue
March 23, 2021
In a new study published in Stem Cell Reports, researchers have developed organoids to replace thyroid function [1]. If this approach is fully fleshed out and successfully brought to the clinic, it may become a true cure for hypothyroidism. A common but harmful affliction Hypothyroidism is
Human Trial Suggests Clearing Plaques Slows Mental Decline
March 22, 2021
Until now, it was unclear as to whether drugs that clear amyloid, which accumulate in the brain during aging and accompany diseases such as Alzheimer’s, have any influence over cognitive decline. Previous studies have aimed to find this out, but results have been inconclusive due to
A Summary of B Cells
March 22, 2021
The immune system as a whole can be broadly separated into two main branches: the innate immune response and the adaptive immune response. The innate immune response is performed by a system that is always present across the body, while the adaptive immune response appears only
Reduced Nicotinamide Mononucleotide Is a New NAD+ Precursor
March 19, 2021
There has been a lot of attention given to the NAD precursors nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR), sold as dietary supplements, to restore nicotinamide adenine dinucleotide (NAD) levels. However, a new study suggests that there could be a new game in town with the
Broadening Longevity Research to Social Factors
March 18, 2021
The time has come for anti-aging research to incorporate behavioral and social science into its agenda, according to Terrie Moffitt, a psychology and neuroscience professor at Duke University [1]. She explains that doing so will help researchers translate fundamental findings into useful therapies and guide us
Would Increased Longevity Be Boring?
March 17, 2021
Everlasting boredom is a common concern when it comes to the idea of extended human lifespans. There are many people who expect life to become empty and meaningless with time because everything has been already experienced; there is nothing else to discover, nothing else can surprise
Quantum Dot Nanomedicine for Longevity Drugs
March 17, 2021
New research in the journal ACS Nano describes a method to improve the efficiency of NMN and metformin in the liver by using a novel nanoparticle delivery method. Nanotechnology in drug delivery Nanotechnology is a broad field that utilizes the unique properties of extraordinarily small materials.
Major Health-Related Data Project Secures Funding in the UK
March 16, 2021
In the UK, the All-Party Parliamentary Group (APPG) for Longevity has secured funding for its Open Life Data project, which aims to create a framework for effective and ethical collection of health-related data on a national level. The UK appears to be one of the first
We Celebrate Our Seventh Birthday!
March 15, 2021
Today, we celebrate our seventh birthday. On this very day, seven years ago, a group of healthy life extensionists decided to put their skin in the game and applied to officially register our organization with the purpose of promoting aging research. The initial founders – Keith
David Sinclair and Peter Attia Co-chair $200m Biotech SPAC
March 12, 2021
Another special purpose acquisition company (SPAC) focused on longevity and rejuvenation biotechnology has appeared recently, and with the addition of research rockstars David Sinclair and Peter Attia, it could mean a bright future for healthy longevity. We recently talked about how SPACs could transform the longevity
Managing Stress Responses to Slow Down Aging
March 11, 2021
Longevity research should better incorporate the effects of stress on aging, argues professor Elissa Epel of the University of California, San Francisco [1]. She proposes using the concept of stress resilience to capture the differences between beneficial and harmful stress and the multi-level response that mediates
A Summary of NAD+ and Human Aging – Part 2
March 10, 2021
Welcome to part two of a two-part series exploring NAD+ biology; you can find part one here. There are already a myriad of excellent reviews on NAD+ biology in general [1-3], so, in this article, we will be mainly focusing on the NAD+ precursor nicotinamide mononucleotide
Longevity Pharmacology with Dr. João Pedro de Magalhães
March 10, 2021
Dr. João Pedro de Magalhães is a Professor at the University of Liverpool, England, where he studies aging and longevity at the genetic level, and he is also an affiliate Principal Investigator in the Neuroendocrinology and Aging Group at the University of Coimbra, Portugal. Dr. de
Binary Clock Predicts Biological Age
March 9, 2021
Scientists have devised a transcriptome-based aging clock that allows for precise measurement of biological age in C. elegans worms and shows promising results in humans as well [1]. The purpose of aging clocks One of the central questions of longevity research is how to measure biological