Category: News
Rejuvenation Roundup July 2023
August 1, 2023
Genetic and epigenetic studies abound this month, with a small molecule study making waves throughout the rejuvenation world. Let’s see what’s happened in July. LEAF News Peter Fedichev Explains His
Genetically Engineering Cells to Respond to Electricity
July 31, 2023
A paper published today in Nature Metabolism has described a method of genetically engineering cells to respond to electrical stimuli, allowing for on-demand gene expression. Finding a better trigger Despite
Young Brain Cells Outcompete Old Cells in a Mouse Model
July 28, 2023
In a mouse model of Huntington’s disease, scientists showed that injected young healthy brain cells can outcompete and eventually replace old, diseased ones. The results might be relevant for other
Neil Riordan on the Rising Tide of Stem Cell Therapies
July 27, 2023
“Stem Cell Therapy: A Rising Tide” by Neil Riordan is a comprehensive exploration of stem cell therapy along with its potential benefits, limitations, and prospects. The father of mesenchymal stem
Psychedelic Drugs for Alzheimer’s Treatment
July 27, 2023
A review article published in European Neuropsychopharmacology has described how and why psychedelic compounds may be useful in treating neurodegenerative diseases such as Alzheimer’s. A question of neuroplasticity Neuroplasticity refers
Some Age-Related Gene Expression Changes May Extend Life
July 26, 2023
In a recent paper published in Nucleic Acids Research, researchers analyzed the organs of several mammalian species, exploring gene expression patterns associated with maximum lifespan and finding surprising correlations [1].
Vigorous Weekend Exercise May Be Enough
July 26, 2023
A new study suggests that “weekend warriors”, people who only exercise for one or two days a week, enjoy similar cardiovascular benefits as those who exercise more regularly [1]. How
Review Links Statins to Insulin Resistance and Diabetes
July 25, 2023
A new systematic review lends support to the idea that statins, which are life-saving cholesterol-lowering drugs, are associated with an increased risk of insulin resistance and type 2 diabetes [1].
Metformin Protects Against Muscle Atrophy in Clinical Trial
July 24, 2023
Researchers publishing in Aging Cell have documented a human clinical trial showing that metformin reduces atrophy caused by long periods of bed rest. A common problem and a well-known diabetes
New System-Specific Epigenetic Clocks Revealed
July 21, 2023
A group of researchers led by Morgan Levine of Altos Labs has created a set of methylation clocks that can detect various aging patterns [1]. The less-than-perfect revolution The discovery
Repairing the Long-Term Damage of Smoking
July 20, 2023
Researchers publishing in Aging Cell have described how treating the increased senescent cell burden that comes with cigarette smoke exposure can repair some of the damage. Senescent cells and COPD
Ending Age-Related Diseases 2023 is Almost Here!
July 19, 2023
Summer is in full swing, and our most important event of the year draws near. In this special edition of our editorial, we want to update you on our
Finding The Genes for Longevity in Mammals
July 19, 2023
Researchers have analyzed the activity of genes in the livers, kidneys, and brains of over a hundred mammals and found genes that are consistently associated with longevity [1]. The search
Rejuvenating Cells Using A New Small Molecule Approach
July 18, 2023
A team led by renowned Harvard geroscientists David Sinclair and Vadim Gladyshev has reported successful chemically induced partial cellular reprogramming in vitro. The researchers have also developed a novel cellular
Making Genetically Engineered Stem Cells Viable
July 17, 2023
Researchers publishing in Cell Stem Cell have announced a new method of accurately and rapidly cloning genetically engineered stem cells. CRISPR is still imperfect While the accuracy of genetic modification
Rejuvenation Roundup July 2023
August 1, 2023
Genetic and epigenetic studies abound this month, with a small molecule study making waves throughout the rejuvenation world. Let’s see what’s happened in July. LEAF News Peter Fedichev Explains His Theory of Aging: Peter Fedichev, co-founder and CEO of Gero, is a relative newcomer to the
Genetically Engineering Cells to Respond to Electricity
July 31, 2023
A paper published today in Nature Metabolism has described a method of genetically engineering cells to respond to electrical stimuli, allowing for on-demand gene expression. Finding a better trigger Despite its futuristic outlook, this line of research is built upon previous work. The idea of an
Young Brain Cells Outcompete Old Cells in a Mouse Model
July 28, 2023
In a mouse model of Huntington’s disease, scientists showed that injected young healthy brain cells can outcompete and eventually replace old, diseased ones. The results might be relevant for other neurodegenerative diseases [1]. When neurons’ helpers fail The non-neuronal cells in the brain are collectively known
Neil Riordan on the Rising Tide of Stem Cell Therapies
July 27, 2023
“Stem Cell Therapy: A Rising Tide” by Neil Riordan is a comprehensive exploration of stem cell therapy along with its potential benefits, limitations, and prospects. The father of mesenchymal stem cell research, Arnold Caplan, dubbed Riordan as a pioneering figure in stem cell research and application.
Psychedelic Drugs for Alzheimer’s Treatment
July 27, 2023
A review article published in European Neuropsychopharmacology has described how and why psychedelic compounds may be useful in treating neurodegenerative diseases such as Alzheimer’s. A question of neuroplasticity Neuroplasticity refers to the ability of neurons to remodel themselves, forming new connections in response to stimuli. Many
Some Age-Related Gene Expression Changes May Extend Life
July 26, 2023
In a recent paper published in Nucleic Acids Research, researchers analyzed the organs of several mammalian species, exploring gene expression patterns associated with maximum lifespan and finding surprising correlations [1]. How and why gene expression changes As organisms age, their gene activity patterns change. To understand
Vigorous Weekend Exercise May Be Enough
July 26, 2023
A new study suggests that “weekend warriors”, people who only exercise for one or two days a week, enjoy similar cardiovascular benefits as those who exercise more regularly [1]. How crucial is a daily run? The consensus of medical studies practically implores people to engage in
Review Links Statins to Insulin Resistance and Diabetes
July 25, 2023
A new systematic review lends support to the idea that statins, which are life-saving cholesterol-lowering drugs, are associated with an increased risk of insulin resistance and type 2 diabetes [1]. Statins’ dark side Statins, drugs that improve the lipid profile by reducing harmful LDL cholesterol, are
Metformin Protects Against Muscle Atrophy in Clinical Trial
July 24, 2023
Researchers publishing in Aging Cell have documented a human clinical trial showing that metformin reduces atrophy caused by long periods of bed rest. A common problem and a well-known diabetes drug Long periods of disuse cause muscles to atrophy and accelerate the age-related muscle wasting known
New System-Specific Epigenetic Clocks Revealed
July 21, 2023
A group of researchers led by Morgan Levine of Altos Labs has created a set of methylation clocks that can detect various aging patterns [1]. The less-than-perfect revolution The discovery that genome methylation patterns correlate with various processes of aging led to the development of methylation
Repairing the Long-Term Damage of Smoking
July 20, 2023
Researchers publishing in Aging Cell have described how treating the increased senescent cell burden that comes with cigarette smoke exposure can repair some of the damage. Senescent cells and COPD Chronic obstructive pulmonary disorder (COPD) and idiopathic pulmonary fibrosis (IPF), both of which are well-known consequences
Ending Age-Related Diseases 2023 is Almost Here!
July 19, 2023
Summer is in full swing, and our most important event of the year draws near. In this special edition of our editorial, we want to update you on our conference and what we have in store for you this year. Can we turn back our
Finding The Genes for Longevity in Mammals
July 19, 2023
Researchers have analyzed the activity of genes in the livers, kidneys, and brains of over a hundred mammals and found genes that are consistently associated with longevity [1]. The search for longevity-associated genes Between the shortest-living and the longest-living mammal, there is a more than 100-fold
Rejuvenating Cells Using A New Small Molecule Approach
July 18, 2023
A team led by renowned Harvard geroscientists David Sinclair and Vadim Gladyshev has reported successful chemically induced partial cellular reprogramming in vitro. The researchers have also developed a novel cellular rejuvenation assay [1]. Smaller than proteins Complete cellular reprogramming using the Yamanaka factors was first accomplished
Making Genetically Engineered Stem Cells Viable
July 17, 2023
Researchers publishing in Cell Stem Cell have announced a new method of accurately and rapidly cloning genetically engineered stem cells. CRISPR is still imperfect While the accuracy of genetic modification through the well-known CRISPR/Cas9 system continues to improve, the technology remains imperfect. Small mistakes were initially