Category: News

White mouse

Rapamycin Rescues Age-Impaired Blood Flow in Mice

Scientists have concluded that rapamycin treatment started in early mid-life can prevent age-related blood flow impairment in the hindlimbs of wild-type, atherosclerotic, and Alzheimer’s model mice [1]. PAD and aging

Heart representation

Heart Organoids May Change Future Research

Researchers publishing in Nature Biotechnology have generated epicardioids, which are pluripotent, self-organizing stem cells that allow for better understanding, research, and potentially prevention and treatment of heart disease. A background

Prizes

Longevity Prize Announces First Winners

The winners of the Hypothesis Prize have been announced as part of the Longevity Prize initiative. This is an important step for funding rejuvenation research and sets a great precedent

RNA transcription

Age-Related Changes in RNA Transcription Speed

Research published yesterday in Nature has described one way in which RNA sequencing changes in the cell with age and how this may be linked to lifespan. Transcriptional elongation Transcriptional

Heart diagnostics

Examining a Factor in the Diabetic Heart

Research published in Heliyon has outlined the effects of F-Klb, a signaling molecule receptor that is released under metabolic stress, on the hearts of diabetic patients. A protector that loses

Airborne particulates

Air Pollution Promotes Cancer Through Inflammation

Researchers have concluded that airborne fine particulate matter, which has been consistently linked to cancer, promotes lung cancer via inflammation and not necessarily via mutagenesis [1]. Not just mutations Common

Keto diet

Low Carb Intake Linked to Insulin Resistance

Scientists have published a new study where they suggest that low carbohydrate consumption is significantly associated with increased insulin resistance in healthy, lean people [1]. Benefits and risks Diet is

Elderly intestines

Young Microbiomes in Very Old People

Research published today in Nature Aging has illustrated how the gut microbiomes of the longest-lived people are more likely to have bacterial populations associated with youth. A known difference This

Bryan Johnson Face

Bryan Johnson And His Race Against Time

Bryan Johnson is an enigma in the longevity space, someone who is difficult to place in a familiar category or determine the net impact of. Johnson is a successful tech

White mouse

Rapamycin Rescues Age-Impaired Blood Flow in Mice

Scientists have concluded that rapamycin treatment started in early mid-life can prevent age-related blood flow impairment in the hindlimbs of wild-type, atherosclerotic, and Alzheimer’s model mice [1]. PAD and aging Peripheral artery disease (PAD) is defined as reduced blood flow to the lower limbs. Age is

Heart representation

Heart Organoids May Change Future Research

Researchers publishing in Nature Biotechnology have generated epicardioids, which are pluripotent, self-organizing stem cells that allow for better understanding, research, and potentially prevention and treatment of heart disease. A background of heart development The epicardium, a layer of cells surrounding the heart, plays a major role

Elderly drinking

Review: Moderate Drinking Doesn’t Lower Mortality

A new comprehensive meta-analysis failed to find any protective effect of moderate drinking on mortality risk [1]. Linear or U-shaped? There is an ancient idea that while excessive drinking will kill you, moderate alcohol consumption is actually good for you, and until recently, it seemed to

Edible mushrooms

Comparing Mushroom and Animal Protein for Muscle Building

Scientists have reported that protein derived from mushrooms (mycoprotein) has a similar impact on muscle mass and strength as animal-based protein in young, healthy people undergoing resistance training [1]. Choosing between animal and non-animal sources Proteins are essential for muscle building, and strong muscles are important

Prizes

Longevity Prize Announces First Winners

The winners of the Hypothesis Prize have been announced as part of the Longevity Prize initiative. This is an important step for funding rejuvenation research and sets a great precedent for future longevity-focused prizes and open science. Introducing the Longevity Prize The Longevity Prize is a

RNA transcription

Age-Related Changes in RNA Transcription Speed

Research published yesterday in Nature has described one way in which RNA sequencing changes in the cell with age and how this may be linked to lifespan. Transcriptional elongation Transcriptional elongation is a fundamental biological process, as it affects the basic steps involved in the production

Heart diagnostics

Examining a Factor in the Diabetic Heart

Research published in Heliyon has outlined the effects of F-Klb, a signaling molecule receptor that is released under metabolic stress, on the hearts of diabetic patients. A protector that loses its effectiveness Fibroblast growth factor 21 (FGF21) is a regulator of metabolism that is produced both

Outdoors

Physical Activity, Sleeping, Sedentary Behavior, and Aging

Regular exercise, getting enough sleep, and avoiding sedentary behavior are frequently reported as being important in determining how slowly we age. A team of researchers recently set out to determine the link between physical activity, sleeping, and sedentary behavior [1]. Finding out if sleep, exercise, and

Airborne particulates

Air Pollution Promotes Cancer Through Inflammation

Researchers have concluded that airborne fine particulate matter, which has been consistently linked to cancer, promotes lung cancer via inflammation and not necessarily via mutagenesis [1]. Not just mutations Common wisdom says that carcinogens increase cancer risk mostly by promoting oncogenic mutations. Research has reported that

Brain synapses

Reducing Axonal Death and Inflammation in Mouse Brains

Researchers have published a study in Aging Cell on how inhibiting the death of axons in the brain protects the brains of old mice from inflammation. Necroptosis in the brain It is well-known that aged organisms have problems with cognitive function, and this is strongly linked

Keto diet

Low Carb Intake Linked to Insulin Resistance

Scientists have published a new study where they suggest that low carbohydrate consumption is significantly associated with increased insulin resistance in healthy, lean people [1]. Benefits and risks Diet is a powerful mediator of health and longevity. While there is broad consensus on what dietary components

Elderly intestines

Young Microbiomes in Very Old People

Research published today in Nature Aging has illustrated how the gut microbiomes of the longest-lived people are more likely to have bacterial populations associated with youth. A known difference This is far from the first study showing a connection between a healthy, youthful microbiome and enhanced

Editorial

We Continue To Engage Growing Audiences About Rejuvenation

For those of us in the Northern Hemisphere, spring has finally arrived, and with it, we have lots of news to share with you! Happy birthday to us! That’s right, folks, it’s our birthday, and we are celebrating nine years of being a non-profit organization that

Bryan Johnson Face

Bryan Johnson And His Race Against Time

Bryan Johnson is an enigma in the longevity space, someone who is difficult to place in a familiar category or determine the net impact of. Johnson is a successful tech entrepreneur of humble origins who sold his company Braintree Venmo to PayPal in 2013 for 800

Swimming in ice

Cold Temperatures Stimulate Lifespan-Associated Protein

A paper published today in Nature Aging describes how cold temperatures stimulate the production of PA28γ, a protein that appears to increase lifespan in worms and cells. An explanation for a commonly held belief Cold temperatures have been associated with longevity for more than a hundred