Category: News

Methuselah's Zoo

Methuselah’s Zoo, a Look at Animal Longevity

To understand human longevity, we need to put it into perspective. Are we relatively long-lived or short-lived creatures? After all, among all the plants and animals in nature, we find

Fat rat

A Link Between Obesity And Joint Degeneration

In a new study published in Scientific Reports, researchers have uncovered the molecular mechanism underlying the link between obesity and joint degeneration [1]. Obesity and osteoarthritis Obesity accelerates aging and

muscle and bone

One Drug to Fight Both Sarcopenia and Osteoporosis

In a new study published in Bone Research, Japanese researchers established a novel drug screening system and identified a promising compound to treat age-associated muscle and bone frailty [1]. Musculoskeletal

sick patient

Early-Onset Cancer Cases Are Rising

In a review paper published in Nature, scientists discuss the problem of the rising burden of early-onset cancer [1]. Not just a disease of aging We tend to think of

Multivitamins

Multivitamin Supplementation Shown to Improve Cognition

In a large randomized, placebo-controlled study, scientists hoped that cocoa extract would improve cognitive function in elderly patients, but instead it was a multivitamin supplement that shined [1]. A two-in-one

Brainwaves

Neuromodulation Improves Memory in Older Adults

A new study published in Nature Neuroscience has shown that neuromodulation of low-frequency neuronal activity in the parietal cortex improved working memory, while high-frequency modulation in the prefrontal cortex improved

Lung cancer

Injectable Cytokine Factories Eradicate Cancer in Mice

Researchers have succeeded in beating a type of cancer previously considered incurable by using microcapsules that contained live cytokine-producing cells [1]. IL-2 is potent but toxic Interleukin-2 (IL-2) therapy was

Methuselah's Zoo

Methuselah’s Zoo, a Look at Animal Longevity

To understand human longevity, we need to put it into perspective. Are we relatively long-lived or short-lived creatures? After all, among all the plants and animals in nature, we find a vast variety of lifespans, from several hours to several millennia, and possibly even more. While

Microplastics

Nanoplastics Cause Mitochondrial Stress in Human Cells

A paper published in Environmental Science and Technology has described some of the effects of nanoplastics on human liver and lung cells [1]. Microplastics and nanoplastics Plastics in the environment are gradually broken down by sunlight, grinding processes, and biological activities into smaller and smaller pieces

Fat rat

A Link Between Obesity And Joint Degeneration

In a new study published in Scientific Reports, researchers have uncovered the molecular mechanism underlying the link between obesity and joint degeneration [1]. Obesity and osteoarthritis Obesity accelerates aging and is associated with several age-associated diseases, including osteoarthritis, an inflammatory condition that leads to joint degeneration.

Longevity Summit Dublin

Research, DeSci, and Advocacy at Longevity Summit Dublin

It was all about collaboration: maybe not a lot of shiny new discoveries and unpublished data, but Longevity Summit Dublin 2022 brought together researchers, investors, and advocates to forge a common vision. More attention is being brought to the last category, as evidenced by our own

Brain genes

Fundamental Metabolic Changes Accompany Alzheimer’s Disease

A paper published in Cell Metabolism has reported on a metabolic shift in neurons derived from patients with Alzheimer’s disease, showing that they express a cancer-like phenotype [1]. Induced neurons Rather than attempting to harvest live neurons from Alzheimer’s patients, the researchers chose to create induced

wearable device

A Wearable Tracker For Metabolites, Nutrients, and Drugs

Today, we want to highlight an interesting development on the wearable diagnostic front: researchers have developed a wearable device that can monitor nutrients, hormones, and drugs [1]. Real-time health monitoring The popularity of medical wearables has increased in recent years. A few decades ago, a complex

B cells

Transplanting B Cells from Old to Young Mice Improves Them

Researchers have recently explored why B cells become less efficient as we age, analyzing how their behavior changes when they are transplanted from aged mice into young mice [1]. The immune system is a comprehensive defense system Our immune systems protect us from disease and are

muscle and bone

One Drug to Fight Both Sarcopenia and Osteoporosis

In a new study published in Bone Research, Japanese researchers established a novel drug screening system and identified a promising compound to treat age-associated muscle and bone frailty [1]. Musculoskeletal system Muscle health and bone health are tightly interconnected. Various muscular dystrophies are a great example:

sick patient

Early-Onset Cancer Cases Are Rising

In a review paper published in Nature, scientists discuss the problem of the rising burden of early-onset cancer [1]. Not just a disease of aging We tend to think of cancer of a disease of aging, and for a good reason: cancer is indeed highly correlated

Severe brain disease

Inflammation Linked To Alzheimer’s and Parkinson’s

In the Journal of Inflammation, researchers from Johns Hopkins University have published a detailed review of the relationship between brain inflammation and the principal diseases of dementia. A focus on genetics and environment One out of twenty Americans over 85 have Parkinson’s disease [1], and seven

Multivitamins

Multivitamin Supplementation Shown to Improve Cognition

In a large randomized, placebo-controlled study, scientists hoped that cocoa extract would improve cognitive function in elderly patients, but instead it was a multivitamin supplement that shined [1]. A two-in-one study Multivitamins are among the most popular dietary supplements, but their effectiveness is often questioned. While

Dividing cell

Stem Cell Activity Regulated By Mitochondrial Protein

Researchers publishing in Cell Stem Cell have found that the mitochondrial protein OPA1 is an integral, regulatory part of muscle stem cell activation, the process by which muscle stem cells proliferate and become active muscle tissue (myogenesis) [1]. Another piece of the puzzle We have recently

Duchenne

Removing Senescent Cells to Alleviate Muscular Dystrophy

A study published in Aging has shown that the removal of senescent cells through senolytics alleviates muscle degeneration in a mouse model of Duchenne muscular dystrophy. A genetic disease with hallmarks of aging Duchenne muscular dystrophy is caused by a mutation that gradually destroys the muscles,

Brainwaves

Neuromodulation Improves Memory in Older Adults

A new study published in Nature Neuroscience has shown that neuromodulation of low-frequency neuronal activity in the parietal cortex improved working memory, while high-frequency modulation in the prefrontal cortex improved long-term memory in older adults [1]. As people age, their cognitive abilities get worse. This includes

Lung cancer

Injectable Cytokine Factories Eradicate Cancer in Mice

Researchers have succeeded in beating a type of cancer previously considered incurable by using microcapsules that contained live cytokine-producing cells [1]. IL-2 is potent but toxic Interleukin-2 (IL-2) therapy was the first anti-cancer immunotherapy approved decades ago. It is based on the ability of this inflammatory