Category: News

Lewy bodies

Developing Nanobodies to Fight Parkinson’s Disease

A team of researchers publishing in Nature Communications has described nanobodies that can destroy the α-synuclein aggregates that characterize Lewy bodies, which are associated with dementia and Parkinson’s disease [1].

Mouse running

Ghrelin Is Associated with Worse Muscle Aging in Mice

A team of researchers publishing through Multidisciplinary Digital Publishing Institute has described an association between the peptide ghrelin and skeletal muscle aging in mice [1]. An appetite stimulant with potential

Rejuvenation Roundup July

Rejuvenation Roundup July 2022

Ending Age-Related Diseases 2022 will occur in less than two weeks, but that’s far from the only thing happening this month, and there’s plenty that happened last month as well.

Mebots

Mebots – Merging Gaming with Fitness

The pandemic has pushed many people indoors, and for many people, this has meant more time watching TV or using the computer. Screen time is now an average of 7

brain vasculature

Loss of IGF-1 May Contribute to Neurovascular Aging

Researchers publishing in GeroScience have reported that the age-related decline in IGF-1 levels is associated with neurovascular aging [1]. IGF-1 and brain vasculature This paper begins with a discussion of

Glutamine

Glutamine Supplementation Has Anti-Aging Potential

A new study published in Frontiers of Pharmacology has shown that glutamine deprivation might speed up aging while glutamine supplementation reduces oxidative stress-induced senescence in mice [1]. Glutamine is an

Back from the dead

Scientists Move the Boundaries of Post-Mortem Recovery

Researchers have been able to achieve substantial recovery of cellular and organismal activity in pigs that had been dead for a full hour [1]. When is it too late? Advances in resuscitation have already moved the boundaries of life and death, making it possible to revive

Lewy bodies

Developing Nanobodies to Fight Parkinson’s Disease

A team of researchers publishing in Nature Communications has described nanobodies that can destroy the α-synuclein aggregates that characterize Lewy bodies, which are associated with dementia and Parkinson’s disease [1]. What are nanobodies? Traditional antibody therapies, while promising in some studies, are too large to enter

Steve Horvath

Steve Horvath on the Present and Future of Epigenetic Clocks

Dr. Steve Horvath hardly needs an introduction, so we will be brief: he is the inventor of the epigenetic clock and, currently, principal investigator at Altos Labs. We talked about the recent developments in this immensely important field, including pan-mammalian clocks, two-species clocks, and single-cell clocks,

Sauna

Sauna Combined with Exercise Improves Cardiovascular Health

In a randomized, controlled trial, scientists have shown that sauna and exercise, when taken together, might have a synergistic, beneficial effect on cardiovascular health and cholesterol levels [1]. Turn up the heat Sauna bathing has been credited with many health benefits [2], predominantly for the cardiovascular

Mouse running

Ghrelin Is Associated with Worse Muscle Aging in Mice

A team of researchers publishing through Multidisciplinary Digital Publishing Institute has described an association between the peptide ghrelin and skeletal muscle aging in mice [1]. An appetite stimulant with potential side effects Ghrelin is a peptide containing 28 amino acids. Its main function is to stimulate

Periodontitis

VitaDAO Backs Research into Chronic Oral Disease

Periodontal disease affects more than 47% of adults aged 30 and over. For people over 65 years of age, that number rises to over 70%, making periodontitis one of the most commonly observed age-related illnesses. Jonathan An’s lab seeks to research inflammation-targeting compounds that can help

Small healthy meal

Caloric Restriction Improves Immune System Function

A new study published in Mechanisms of Aging and Development has shown that caloric restriction effectively restores T cell abundance in aged mice [1]. Is it really just about getting fewer calories? Caloric restriction has become a well-known anti-aging intervention, as it can reverse several hallmarks

Sophora Japonica

Hesperetin Upregulates Metabolism and Longevity in Mice

Researchers publishing in Journal of Biomedical Science have concluded that hesperetin, a compound found in various herbs, improves longevity in mice by promoting the expression of the pro-longevity gene Cisd2. Mitochondria and Cisd2 This paper begins with an explanation of mitochondrial dysfunction, one of the hallmarks

No results

Vitamin D Fails to Improve Bone Health in Mega-Study

A high-quality, randomized, controlled trial found no effect of vitamin D supplementation or blood levels on the incidence of fractures in an aging population [1]. The common perception doesn’t match the science It’s a long-held aphorism that vitamin D is good for bone health. This has

Rejuvenation Roundup July

Rejuvenation Roundup July 2022

Ending Age-Related Diseases 2022 will occur in less than two weeks, but that’s far from the only thing happening this month, and there’s plenty that happened last month as well. Here’s the latest rejuvenation news from July. LEAF News Health Benefits of Cocoa: Ryan O’Shea explains

Mebots

Mebots – Merging Gaming with Fitness

The pandemic has pushed many people indoors, and for many people, this has meant more time watching TV or using the computer. Screen time is now an average of 7 hours per day, which has led to all-time highs of obesity, worsening health, anxiety, and depression.

Future Clock

Epigenetic Age Acceleration Is Correlated with Mortality

In an important step for the longevity field, scientists have found that epigenetic age acceleration, as measured by four popular methylation clocks, is correlated with aging and mortality in humans [1]. Lack of human data Studying aging obviously requires having reliable biomarkers of aging. Epigenetic clocks

brain vasculature

Loss of IGF-1 May Contribute to Neurovascular Aging

Researchers publishing in GeroScience have reported that the age-related decline in IGF-1 levels is associated with neurovascular aging [1]. IGF-1 and brain vasculature This paper begins with a discussion of neurovascular coupling (NVC) and its relationship to vascular dementia. Blood flow to the brain is extremely

Glutamine

Glutamine Supplementation Has Anti-Aging Potential

A new study published in Frontiers of Pharmacology has shown that glutamine deprivation might speed up aging while glutamine supplementation reduces oxidative stress-induced senescence in mice [1]. Glutamine is an amino acid of paramount importance for many cellular functions. It is involved in the synthesis of

Elderly poverty

Social Frailty Is Correlated with All-Cause Mortality

Scientists have shown that social frailty – a composite index based on income level, household status, and social activity – significantly affects all-cause mortality in the elderly, with poverty being the predominant factor [1]. There is more than one way to be frail Physical frailty is