Category: News
Intervertebral Disc Rejuvenation Using Yamanaka Factors
March 23, 2022
Partial cellular reprogramming using Yamanka factors has become increasingly prominent in the world of aging research. A new study suggests that transient exposure to the Yamanaka factors might be the
Fasting During Ramadan and Acute Kidney Injury Incidence
March 23, 2022
A cohort study that was published in BioMed Central by Dr. Alsayyari and colleagues examined fasting on acute kidney injury incidence [1]. Background Fasting during the month of Ramandan is
Glutathione Extends Lifespan in Mice by 24%
March 22, 2022
In a study conducted by scientists from Baylor College of Medicine in Houston, supplementation of glutathione had a drastic effect on the lifespan of wild-type mice, both male and female
Fighting COVID-19 by Counteracting Aging
March 21, 2022
A research paper that has just been peer reviewed and published in Nature has described how disrupting an immune pathway that is upregulated in aging decreases the lethality of COVID-19
Dog Ownership Lowers Risk of Disability in Old Age
March 18, 2022
In a new population study, scientists show that dog ownership is associated with a lower risk of developing disability in old age, though it does not affect all-cause mortality [1].
The Growing Increase in Cognitive Reserve
March 17, 2022
A study published in Brain Sciences has shown that mild cognitive impairment is less than half as common now as it was twenty years ago. Two cohorts, one study This
Microglia Depletion Decreases Neuroinflammation in Mice
March 16, 2022
Scientists show that when done right, partial elimination of microglia, the immune cells of the brain, lowers age-related inflammation and cellular senescence [1]. Aging makes microglia bitter Brain health is
Clinical Trials Targeting Aging
March 16, 2022
A miniature review of clinical trials targeting aging was published in Frontiers in Aging by Dr. Morten Scheibye-Knudsen and colleagues [1]. This review specifically focuses on interventions that have shown
Dina Radenkovic on the Root Cause of Gender Inequality
March 15, 2022
Our interviewee today holds that female reproductive aging, or ovarian aging, is accelerated compared to other organs and that it has a deep impact both on the lives and health
Using Gene Expression to Target Senescent Cells
March 14, 2022
An open access study published in iScience has discussed the development of senolytics to target particular genes that are upregulated in cellular senescence. Understanding senescence, cell by cell In our
Tuberculosis Is Associated with Epigenetic Aging
March 11, 2022
Publishing in Aging, a team of researchers has explained the relationship between tuberculosis (TB) and multiple aspects of aging, including epigenetic alterations and the senescence-associated secretory phenotype (SASP). A disease
Long-Term Cellular Reprogramming Causes Rejuvenation in Mice
March 11, 2022
Scientists have shown that in vivo partial cellular reprogramming can be safe and effective in an animal model, although the rejuvenation was mostly limited to long-term treatments and two tissue
Meat Consumption Increases Risk of Some Types of Cancer
March 10, 2022
In a new population study, scientists have found more evidence that consuming a lot of meat might not be a good idea, though the association between meat and cancer depends
Vitamin D Dosing Safety in a Randomized, Controlled Trial
March 9, 2022
New data has been released from the Vitamin D Type 2 Diabetes (D2d) study [1]. This study is a randomized, controlled trial that includes overweight and obese people studied at
Dr. Simon Melov on Single Cell Genomics
March 8, 2022
Dr. Simon Melov is a professor at the Buck Institute for Research on Aging. His lab is working on identifying the molecular hallmarks of aging, specifically in the context of
Intervertebral Disc Rejuvenation Using Yamanaka Factors
March 23, 2022
Partial cellular reprogramming using Yamanka factors has become increasingly prominent in the world of aging research. A new study suggests that transient exposure to the Yamanaka factors might be the solution to intervertebral disc degeneration [1]. Partial cellular reprogramming with Yamanaka factors We have talked previously
Fasting During Ramadan and Acute Kidney Injury Incidence
March 23, 2022
A cohort study that was published in BioMed Central by Dr. Alsayyari and colleagues examined fasting on acute kidney injury incidence [1]. Background Fasting during the month of Ramandan is a obligation in Islam with exceptions, such as for chronic illness that has a poor prognosis
Glutathione Extends Lifespan in Mice by 24%
March 22, 2022
In a study conducted by scientists from Baylor College of Medicine in Houston, supplementation of glutathione had a drastic effect on the lifespan of wild-type mice, both male and female [1]. Dangerous species Oxidative stress happens when the delicate balance between the production and degradation of
Fighting COVID-19 by Counteracting Aging
March 21, 2022
A research paper that has just been peer reviewed and published in Nature has described how disrupting an immune pathway that is upregulated in aging decreases the lethality of COVID-19 in a mouse model. Mice with COVID-19 As the researchers explain, normal mice do not use
Dog Ownership Lowers Risk of Disability in Old Age
March 18, 2022
In a new population study, scientists show that dog ownership is associated with a lower risk of developing disability in old age, though it does not affect all-cause mortality [1]. 1500+ dogs, and some cats too What can be more stereotypical than an old lady with
The Growing Increase in Cognitive Reserve
March 17, 2022
A study published in Brain Sciences has shown that mild cognitive impairment is less than half as common now as it was twenty years ago. Two cohorts, one study This study used data from the Interdisciplinary Longitudinal Study of Adult Development and Aging (ILSE), which began
Microglia Depletion Decreases Neuroinflammation in Mice
March 16, 2022
Scientists show that when done right, partial elimination of microglia, the immune cells of the brain, lowers age-related inflammation and cellular senescence [1]. Aging makes microglia bitter Brain health is of utmost importance for geroscientists, since the brain is the one organ that cannot be replaced,
Clinical Trials Targeting Aging
March 16, 2022
A miniature review of clinical trials targeting aging was published in Frontiers in Aging by Dr. Morten Scheibye-Knudsen and colleagues [1]. This review specifically focuses on interventions that have shown strong clinical evidence that they impact aging. Caloric restriction We have previously discussed the effects of
Dina Radenkovic on the Root Cause of Gender Inequality
March 15, 2022
Our interviewee today holds that female reproductive aging, or ovarian aging, is accelerated compared to other organs and that it has a deep impact both on the lives and health of women and on our society as a whole. Nevertheless, ovarian aging continues to be underresearched,
Using Gene Expression to Target Senescent Cells
March 14, 2022
An open access study published in iScience has discussed the development of senolytics to target particular genes that are upregulated in cellular senescence. Understanding senescence, cell by cell In our earlier interview with Simon Melov of the Buck Institute, the lead researcher of this paper, Dr.
Tuberculosis Is Associated with Epigenetic Aging
March 11, 2022
Publishing in Aging, a team of researchers has explained the relationship between tuberculosis (TB) and multiple aspects of aging, including epigenetic alterations and the senescence-associated secretory phenotype (SASP). A disease known to cause long-term harm Tuberculosis, a disease that has proliferated around the world, kills 1.4
Long-Term Cellular Reprogramming Causes Rejuvenation in Mice
March 11, 2022
Scientists have shown that in vivo partial cellular reprogramming can be safe and effective in an animal model, although the rejuvenation was mostly limited to long-term treatments and two tissue types [1]. There and back again Cellular reprogramming sounds like a technology from Star Trek, and
Meat Consumption Increases Risk of Some Types of Cancer
March 10, 2022
In a new population study, scientists have found more evidence that consuming a lot of meat might not be a good idea, though the association between meat and cancer depends on multiple factors [1]. Diet and health Given that lifestyle changes may be the only anti-aging
Vitamin D Dosing Safety in a Randomized, Controlled Trial
March 9, 2022
New data has been released from the Vitamin D Type 2 Diabetes (D2d) study [1]. This study is a randomized, controlled trial that includes overweight and obese people studied at 22 academic medical centers in the United States. This data was collected between October 2013 and
Dr. Simon Melov on Single Cell Genomics
March 8, 2022
Dr. Simon Melov is a professor at the Buck Institute for Research on Aging. His lab is working on identifying the molecular hallmarks of aging, specifically in the context of cellular senescence. Recently, the lab published a paper in which it announced a discovery of a