Category: News
Senolytics Restore α-Klotho in Mice and Humans
April 6, 2022
New senolytics data was released from Dr. James L. Kirkland’s Mayo Clinic lab and published in The Lancet [1]. Prior studies have shown that α-Klotho protein decreases with age in
New Candidate Drug Extends Lifespan in Male Mice
April 5, 2022
Scientists from Mayo Clinic have significantly extended lifespan in male mice by inhibiting the enzyme CD38, which lowers NAD levels [1]. The age-related decline of nicotinamide dinucleotide (NAD) has been
Corylin Shown to Affect Multiple Processes of Aging
April 4, 2022
A new publication in Nature Communications has revealed that corylin, which is derived from the Chinese herb Psoralea corylifolia, increases the lifespan of model organisms through well-known pathways of aging.
Metformin in Fathers Linked to Birth Defects
April 1, 2022
A large-cohort population study from Denmark has linked metformin to a 40% increase in the risk of birth defects when taken by fathers during the spermatozoa development period [1]. A
Raiany Romanni on the Ethical Aspects of Life Extension
April 1, 2022
Raiany Romanni is a Harvard Kennedy Fellow in Effective Altruism, an A360 Scholar, a Stanford Existential Risk Fellow, and a bioethicist. She is currently working on a non-fiction book aimed
Rejuvenation Roundup March 2022
April 1, 2022
March was a productive month for aging research, including new information coming out about the popular supplement glutathione and insights into what leads to cognitive decline. Here’s what happened in
Caloric Consumption Affects Caloric Restriction in Mice
March 31, 2022
Publishing in Aging, researchers from the Chengdu Jinjiang Hospital in China have discovered that caloric restriction is less effective on mice previously fed a high-calorie diet. Well-known effects In their
Life Extension and Anti-Aging Have a Branding Problem
March 30, 2022
It seems bizarre that in 2022, some biotech companies interested in doing something about aging are still saying that they are not. Cellular rejuvenation seems to be the latest buzzword
Oleanoic Acid Protects Against Cardiac Aging in Mice
March 29, 2022
Scientists have shown that oleanoic acid, a nutrient most associated with olive oil, greatly improves numerous markers of cardiac health in aging mice [1]. is a nutrient abundant in some
A Common Amyloid Between Brain Diseases
March 28, 2022
Research funded by the National Institutes of Health and published in Cell has thoroughly described a little-known amyloid aggregate that accumulates in the brains of people suffering from multiple proteostasis-related
Anti-Inflammatory Diet Lowers Risk of Dementia
March 25, 2022
In a population study, scientists have found that consuming foods associated with a low Diet Inflammatory Index substantially lowers the risk of dementia [1]. Aging is accompanied by an increase
Plant Compound Shown to Ameliorate Brain Injury
March 24, 2022
Publishing in Aging, a team of Taiwanese researchers has found that a chemical derived from Polygonum multiflorum, a herb native to southeastern China, aids in recovery from traumatic brain injury
Intervertebral Disc Rejuvenation Using Yamanaka Factors
March 23, 2022
Partial cellular reprogramming using Yamanka factors has become increasingly prominent in the world of aging research. A new study suggests that transient exposure to the Yamanaka factors might be the
Fasting During Ramadan and Acute Kidney Injury Incidence
March 23, 2022
A cohort study that was published in BioMed Central by Dr. Alsayyari and colleagues examined fasting on acute kidney injury incidence [1]. Background Fasting during the month of Ramandan is
Glutathione Extends Lifespan in Mice by 24%
March 22, 2022
In a study conducted by scientists from Baylor College of Medicine in Houston, supplementation of glutathione had a drastic effect on the lifespan of wild-type mice, both male and female
Senolytics Restore α-Klotho in Mice and Humans
April 6, 2022
New senolytics data was released from Dr. James L. Kirkland’s Mayo Clinic lab and published in The Lancet [1]. Prior studies have shown that α-Klotho protein decreases with age in mice and humans [2,3]. It has also been demonstrated that mice that lack α-Klotho have shorter
New Candidate Drug Extends Lifespan in Male Mice
April 5, 2022
Scientists from Mayo Clinic have significantly extended lifespan in male mice by inhibiting the enzyme CD38, which lowers NAD levels [1]. The age-related decline of nicotinamide dinucleotide (NAD) has been associated with various metabolic abnormalities, age-related diseases, and fitness loss. Increasing NAD levels is considered a
Corylin Shown to Affect Multiple Processes of Aging
April 4, 2022
A new publication in Nature Communications has revealed that corylin, which is derived from the Chinese herb Psoralea corylifolia, increases the lifespan of model organisms through well-known pathways of aging. Finding corylin This study did not begin with an examination of corylin or even a look
Metformin in Fathers Linked to Birth Defects
April 1, 2022
A large-cohort population study from Denmark has linked metformin to a 40% increase in the risk of birth defects when taken by fathers during the spermatozoa development period [1]. A drug linked to longevity Metformin is an anti-diabetes drug that drew geroscientists’ attention after studies had
Raiany Romanni on the Ethical Aspects of Life Extension
April 1, 2022
Raiany Romanni is a Harvard Kennedy Fellow in Effective Altruism, an A360 Scholar, a Stanford Existential Risk Fellow, and a bioethicist. She is currently working on a non-fiction book aimed at catalyzing the ethics of longevity research, while suggesting that aging is the costliest of all
Rejuvenation Roundup March 2022
April 1, 2022
March was a productive month for aging research, including new information coming out about the popular supplement glutathione and insights into what leads to cognitive decline. Here’s what happened in the rejuvenation world this month. LEAF News EARD2021 Daniel Ives on Genomic Aging Clocks: Daniel Ives
Caloric Consumption Affects Caloric Restriction in Mice
March 31, 2022
Publishing in Aging, researchers from the Chengdu Jinjiang Hospital in China have discovered that caloric restriction is less effective on mice previously fed a high-calorie diet. Well-known effects In their introduction, the researchers discuss what caloric restriction is known to do, citing papers that show its
Life Extension and Anti-Aging Have a Branding Problem
March 30, 2022
It seems bizarre that in 2022, some biotech companies interested in doing something about aging are still saying that they are not. Cellular rejuvenation seems to be the latest buzzword and an attempt to rebrand and escape the stigma of anti-aging. Genentech is another cellular rejuvenation
Oleanoic Acid Protects Against Cardiac Aging in Mice
March 29, 2022
Scientists have shown that oleanoic acid, a nutrient most associated with olive oil, greatly improves numerous markers of cardiac health in aging mice [1]. is a nutrient abundant in some foods, particularly olive oil. Olive oil has been shown to have health benefits compared to most
A Common Amyloid Between Brain Diseases
March 28, 2022
Research funded by the National Institutes of Health and published in Cell has thoroughly described a little-known amyloid aggregate that accumulates in the brains of people suffering from multiple proteostasis-related neurological disorders. Three classes of pathology, one protein fragment The authors of this study list three
Anti-Inflammatory Diet Lowers Risk of Dementia
March 25, 2022
In a population study, scientists have found that consuming foods associated with a low Diet Inflammatory Index substantially lowers the risk of dementia [1]. Aging is accompanied by an increase in chronic, low-grade inflammation, known as inflammaging, which has been linked to multiple age-related diseases. Inflammaging
Plant Compound Shown to Ameliorate Brain Injury
March 24, 2022
Publishing in Aging, a team of Taiwanese researchers has found that a chemical derived from Polygonum multiflorum, a herb native to southeastern China, aids in recovery from traumatic brain injury and encourages brain regeneration. The problem of glutamate Traumatic brain injury (TBI), the infliction of tissue
Intervertebral Disc Rejuvenation Using Yamanaka Factors
March 23, 2022
Partial cellular reprogramming using Yamanka factors has become increasingly prominent in the world of aging research. A new study suggests that transient exposure to the Yamanaka factors might be the solution to intervertebral disc degeneration [1]. Partial cellular reprogramming with Yamanaka factors We have talked previously
Fasting During Ramadan and Acute Kidney Injury Incidence
March 23, 2022
A cohort study that was published in BioMed Central by Dr. Alsayyari and colleagues examined fasting on acute kidney injury incidence [1]. Background Fasting during the month of Ramandan is a obligation in Islam with exceptions, such as for chronic illness that has a poor prognosis
Glutathione Extends Lifespan in Mice by 24%
March 22, 2022
In a study conducted by scientists from Baylor College of Medicine in Houston, supplementation of glutathione had a drastic effect on the lifespan of wild-type mice, both male and female [1]. Dangerous species Oxidative stress happens when the delicate balance between the production and degradation of