Category: Biology of Aging
Scientists Eliminate Cancer Using Evolutionary Principles
July 9, 2024
A new study describes a method of genetically modifying a fraction of tumor cells, programming them to self-destruct and take therapy-resistant cells with them [1]. Resisting the resistance Advanced solid
A Molecular Reason Why Exercise Fights Senescence
July 8, 2024
Researchers publishing in Aging have found a molecule linking exercise to the inhibition of cellular senescence, one of the hallmarks of aging. Exercise against senescence We recently reported on a
Novel Drug Suppresses Metastatic Cancer in Mice
July 5, 2024
Scientists have found a small molecule that turns an anti-apoptotic protein into a pro-apoptotic one, protecting against deadly metastases in a mouse model of human triple-negative breast cancer and, potentially,
A New Target for Chronic Lung Diseases
July 4, 2024
Revealing their findings in Aging Cell, researchers have found a new biochemical target for chronic obstructive pulmonary disease (COPD). Smoking is only one cause COPD, which is characterized by bouts
Recurrent Pregnancy Loss Associated with Increased Dementia
July 3, 2024
A recent paper in the European Journal of Epidemiology reported that recurrent miscarriage and stillbirths are associated with the occurrence of dementia, but there was insufficient evidence to establish such
Longevity and DeSci Recap – June 2024
July 2, 2024
This summer season is red hot in the world of longevity. Packed with interesting events, investments and new research proposals, the future of longevity is becoming today’s reality. Join us
Nicotinamide Riboside Improves Walking in Clinical Trial
July 1, 2024
Researchers publishing in Nature Communications have found that nicotinamide riboside (NR) improves walking distance for people who have peripheral artery disease (PAD) in the legs. When the arms and legs
Developing a New Aging Clock for Medical Professionals
June 30, 2024
In Nature Aging, researchers have published the creation of a new clock that uses multiple metrics to evaluate biological aging. What’s worth measuring? Multiple metrics have been used to measure
Encouraging Mitochondrial Maintenance to Fight Senescence
June 27, 2024
Researchers have published a method of rescuing cells from damaged mitochondria and cellular senescence, potentially alleviating major aspects of aging. Bad mitochondria must be consumed A core part of autophagy
Blueberry Polyphenol May Relieve Plastic-Caused Sperm Damage
June 26, 2024
A recent paper has investigated the impact of polystyrene nanoplastics on the molecular processes of male reproductive tissues in mice [1]. Health risks of micro- and nanoplastics Microplastic and nanoplastic
Study Links Stress to Mitochondrial Dysfunction in the Brain
June 25, 2024
For the first time, scientists have shown that the abundance of proteins needed for mitochondrial energy production in human brains is linked to perceived psychosocial experiences [1]. Picking the brains
New Drug Restores Telomerase, Improves Cognition in Mice
June 24, 2024
Scientists have identified a small molecule that upregulates telomerase reverse transcriptase (TERT) in multiple tissues, improving health and cognition in old mice. Telomere attrition and health The enzyme telomerase can
A Reason Why Livers Accumulate Fat with Age
June 20, 2024
Researchers have discovered one of the reasons why fatty liver disease, even without alcohol consumption, increases with aging. The earliest stage of fatty liver disease Nonalcoholic fatty liver disease (NAFLD)
Combating How Space Travel Weakens Immune Function
June 19, 2024
It has been known for many years that microgravity in space interferes with human physiology in negative ways. As early as the first Apollo missions, astronauts experienced heart rhythm issues,
A Protein Necessary for Corneal Healing
June 18, 2024
Researchers have discovered a protein that is necessary for proper healing of damaged corneal tissue and that this protein decreases with age. Repairing a shield that is easy to damage
Scientists Eliminate Cancer Using Evolutionary Principles
July 9, 2024
A new study describes a method of genetically modifying a fraction of tumor cells, programming them to self-destruct and take therapy-resistant cells with them [1]. Resisting the resistance Advanced solid tumors remain the main challenge for modern oncology. It’s hard to deliver a therapy to all
A Molecular Reason Why Exercise Fights Senescence
July 8, 2024
Researchers publishing in Aging have found a molecule linking exercise to the inhibition of cellular senescence, one of the hallmarks of aging. Exercise against senescence We recently reported on a team of researchers looking to protect against chronic obstructive pulmonary disease (COPD) by focusing on possible
Novel Drug Suppresses Metastatic Cancer in Mice
July 5, 2024
Scientists have found a small molecule that turns an anti-apoptotic protein into a pro-apoptotic one, protecting against deadly metastases in a mouse model of human triple-negative breast cancer and, potentially, in other cancers [1]. Small but mighty With cutting-edge cancer treatments now including things like antibodies
A New Target for Chronic Lung Diseases
July 4, 2024
Revealing their findings in Aging Cell, researchers have found a new biochemical target for chronic obstructive pulmonary disease (COPD). Smoking is only one cause COPD, which is characterized by bouts of lung problems, has only limited treatments, is progressive and currently incurable, and often occurs in
Recurrent Pregnancy Loss Associated with Increased Dementia
July 3, 2024
A recent paper in the European Journal of Epidemiology reported that recurrent miscarriage and stillbirths are associated with the occurrence of dementia, but there was insufficient evidence to establish such a connection between infertility and dementia [1]. Sex-specific differences in dementia risk Dementia affects women more
Longevity and DeSci Recap – June 2024
July 2, 2024
This summer season is red hot in the world of longevity. Packed with interesting events, investments and new research proposals, the future of longevity is becoming today’s reality. Join us as we run through the happenings of June 2024 and what’s been going on in the
Nicotinamide Riboside Improves Walking in Clinical Trial
July 1, 2024
Researchers publishing in Nature Communications have found that nicotinamide riboside (NR) improves walking distance for people who have peripheral artery disease (PAD) in the legs. When the arms and legs don’t get enough blood Ischemia, the failure of blood vessels to deliver sufficient oxygen and nutrients,
Developing a New Aging Clock for Medical Professionals
June 30, 2024
In Nature Aging, researchers have published the creation of a new clock that uses multiple metrics to evaluate biological aging. What’s worth measuring? Multiple metrics have been used to measure aging. The most commonly known in the literature are the epigenetic clocks, such as GrimAge and
Encouraging Mitochondrial Maintenance to Fight Senescence
June 27, 2024
Researchers have published a method of rescuing cells from damaged mitochondria and cellular senescence, potentially alleviating major aspects of aging. Bad mitochondria must be consumed A core part of autophagy involves selective autophagy receptors (SARs), which build the autophagosomes in which the organelles are consumed [1].
Blueberry Polyphenol May Relieve Plastic-Caused Sperm Damage
June 26, 2024
A recent paper has investigated the impact of polystyrene nanoplastics on the molecular processes of male reproductive tissues in mice [1]. Health risks of micro- and nanoplastics Microplastic and nanoplastic contamination is a worldwide public health concern for a good reason. Numerous research papers have associated
Study Links Stress to Mitochondrial Dysfunction in the Brain
June 25, 2024
For the first time, scientists have shown that the abundance of proteins needed for mitochondrial energy production in human brains is linked to perceived psychosocial experiences [1]. Picking the brains Negative psychosocial experiences have been linked to health problems by numerous studies. However, not enough is
New Drug Restores Telomerase, Improves Cognition in Mice
June 24, 2024
Scientists have identified a small molecule that upregulates telomerase reverse transcriptase (TERT) in multiple tissues, improving health and cognition in old mice. Telomere attrition and health The enzyme telomerase can prevent telomere attrition from happening by extending the length of telomeres. However, in most multicellular organisms,
A Reason Why Livers Accumulate Fat with Age
June 20, 2024
Researchers have discovered one of the reasons why fatty liver disease, even without alcohol consumption, increases with aging. The earliest stage of fatty liver disease Nonalcoholic fatty liver disease (NAFLD) begins with steatosis, the accumulation of fatty tissues in an organ [1], which can then progress
Combating How Space Travel Weakens Immune Function
June 19, 2024
It has been known for many years that microgravity in space interferes with human physiology in negative ways. As early as the first Apollo missions, astronauts experienced heart rhythm issues, low blood pressure, inner ear problems, and bone loss. Researchers at the Buck Institute have published
A Protein Necessary for Corneal Healing
June 18, 2024
Researchers have discovered a protein that is necessary for proper healing of damaged corneal tissue and that this protein decreases with age. Repairing a shield that is easy to damage The corneal epithelium covers the cornea, which focuses light onto the retina of the eye. Although