Category: Research
Targeting Age-Related Metabolic Shifts in the Brain
May 17, 2023
Publishing in Aging, a team of Chilean researchers has described a relationship between gene shifts in the brain and neurons not getting the energy they need. Greedy glia To perform
Building Artificial Organoids to Study Diseases
May 15, 2023
In an open-access paper published in Cell Stem Cell this month, researchers have explained how organoids derived from human pluripotent stem cells (hPSCs) are being used to analyze diseases and
Destroying ‘Zombie’ Cells for Cardiovascular Health
May 12, 2023
Researchers have demonstrated that two senolytic drugs might improve how the heart repairs itself by destroying senescent cells [1]. These harmful cells are associated with many age-related diseases, including cardiovascular
Protecting Mass-Produced Stem Cells from the Immune System
May 11, 2023
Researchers publishing in Nature Biotechnology have demonstrated a method of protecting mass-produced stem cells from the immune system, with strongly positive results in two different animal models. Fake ID for
Irina Conboy on Academic Publishing
May 10, 2023
Today, we are talking with Dr. Irina Conboy, Editor-in-Chief of the journal Rejuvenation Research about impact and other aspects of journal publishing. This journal is an important academic publication for
Gene Therapy Ameliorates Sarcopenia in Old Mice
May 8, 2023
A paper published in Aging has detailed how gene therapy has been used to treat sarcopenia in wild-type mice, and the results are positive. A lack of effective treatments As
Using Machine Learning to Find Senolytics
May 4, 2023
Research published today in Nature Aging has described a machine learning algorithm that finds senescent cell-removing drugs (senolytics) and compared the algorithm’s discoveries to existing compounds. A quest for effective
AI Better Than Humans At Healthcare Questions
May 3, 2023
Scientists have compared doctor-written and chatbot-generated responses to healthcare-related questions, and the results don’t look good for Team Human [1]. Ask your doctor? Access to healthcare has been linked to
Flavonols, Especially Quercetin, Linked to Less Frailty
May 2, 2023
In a new prospective cohort study, a higher intake of flavonols, and quercetin in particular, was linked to a significant decrease in the risk of frailty [1]. Flavonoids: not just
Netrin-1 Rescues Blood Stem Cells in Mice
April 28, 2023
Scientists have discovered that the protein Netrin-1 alleviates the age-related decline in hematopoietic stem cell function in mice, enhancing HSC transplantation and protecting these mice from the harmful effects of
Hair Pigment Stem Cells May Work Differently
April 27, 2023
Researchers publishing in Nature have made the surprising discovery that pigmentation cells (melanocytes) can naturally transition back into the stem cell state in a process called dedifferentiation. A kinship with
Zuzalu: The Experimental Pop-Up City With a Longevity Focus
April 27, 2023
The decentralized autonomous organization VitaDAO is supporting longevity realated initiatives at Zuzalu, a pop-up mini-city event in Montenegro, which aims to create a unique jurisdiction for medical innovation within a
What AI Technology Is Doing for Longevity Now
April 26, 2023
In March 2023, MIT Technology Review revealed that Sam Altman, the CEO of OpenAI (ChatGPT), was the mystery investor behind the $180 million investment into stealth startup Retro Biosciences, a
Simply Being Overweight May Not Be Harmful in Aging
April 26, 2023
According to a new large-scale populational study, being overweight is not associated with either significant risks or benefits between the ages of 45 and 85. Obesity, however, is a clear
Reprogramming Fibroblasts in Vivo for Heart Repair
April 25, 2023
Scientists from Duke University have found a way to make adult fibroblasts differentiate into cardiomyocytes, which might help develop better heart attack treatments [1]. The imperfect repair Myocardial infarction, or
Targeting Age-Related Metabolic Shifts in the Brain
May 17, 2023
Publishing in Aging, a team of Chilean researchers has described a relationship between gene shifts in the brain and neurons not getting the energy they need. Greedy glia To perform various maintenance and protective tasks, the brain contains a large population of microglia alongside its neurons.
Building Artificial Organoids to Study Diseases
May 15, 2023
In an open-access paper published in Cell Stem Cell this month, researchers have explained how organoids derived from human pluripotent stem cells (hPSCs) are being used to analyze diseases and develop treatments. Different sources for different conditions This review includes both human embryonic stem cells (hESCs),
Destroying ‘Zombie’ Cells for Cardiovascular Health
May 12, 2023
Researchers have demonstrated that two senolytic drugs might improve how the heart repairs itself by destroying senescent cells [1]. These harmful cells are associated with many age-related diseases, including cardiovascular disease. Zombie cells that refuse to die As we age, our bodies accumulate senescent cells, often
Protecting Mass-Produced Stem Cells from the Immune System
May 11, 2023
Researchers publishing in Nature Biotechnology have demonstrated a method of protecting mass-produced stem cells from the immune system, with strongly positive results in two different animal models. Fake ID for the immune system While it would be ideal to create stem cells from each person’s existing
Irina Conboy on Academic Publishing
May 10, 2023
Today, we are talking with Dr. Irina Conboy, Editor-in-Chief of the journal Rejuvenation Research about impact and other aspects of journal publishing. This journal is an important academic publication for our field and publishes many papers focused on aging and rejuvenation research. Hi, Irina, and thanks
Gene Therapy Ameliorates Sarcopenia in Old Mice
May 8, 2023
A paper published in Aging has detailed how gene therapy has been used to treat sarcopenia in wild-type mice, and the results are positive. A lack of effective treatments As expected with papers of this kind, the researchers begin by discussing frailty and sarcopenia, the age-related
Using Machine Learning to Find Senolytics
May 4, 2023
Research published today in Nature Aging has described a machine learning algorithm that finds senescent cell-removing drugs (senolytics) and compared the algorithm’s discoveries to existing compounds. A quest for effective therapeutics After covering familiar territory regarding senescent cells, this paper begins with a discussion of existing
AI Better Than Humans At Healthcare Questions
May 3, 2023
Scientists have compared doctor-written and chatbot-generated responses to healthcare-related questions, and the results don’t look good for Team Human [1]. Ask your doctor? Access to healthcare has been linked to longer lifespan, and good healthcare often starts with a good initial consultation. A group of researchers,
Flavonols, Especially Quercetin, Linked to Less Frailty
May 2, 2023
In a new prospective cohort study, a higher intake of flavonols, and quercetin in particular, was linked to a significant decrease in the risk of frailty [1]. Flavonoids: not just flavor Flavonoids are a class of polyphenolic compounds that include flavanols, flavonols, flavones, anthocyanins, and some
Netrin-1 Rescues Blood Stem Cells in Mice
April 28, 2023
Scientists have discovered that the protein Netrin-1 alleviates the age-related decline in hematopoietic stem cell function in mice, enhancing HSC transplantation and protecting these mice from the harmful effects of chemotherapy [1]. (Not) a niche problem Declining stem cell function (stem cell exhaustion) is linked to
Hair Pigment Stem Cells May Work Differently
April 27, 2023
Researchers publishing in Nature have made the surprising discovery that pigmentation cells (melanocytes) can naturally transition back into the stem cell state in a process called dedifferentiation. A kinship with hair follicle cells These researchers begin their study by discussing stem cells and their proliferation. In
Zuzalu: The Experimental Pop-Up City With a Longevity Focus
April 27, 2023
The decentralized autonomous organization VitaDAO is supporting longevity realated initiatives at Zuzalu, a pop-up mini-city event in Montenegro, which aims to create a unique jurisdiction for medical innovation within a more effective regulatory framework. A platform for longevity events and workshops VitaDAO is hosting unique, longevity-oriented
What AI Technology Is Doing for Longevity Now
April 26, 2023
In March 2023, MIT Technology Review revealed that Sam Altman, the CEO of OpenAI (ChatGPT), was the mystery investor behind the $180 million investment into stealth startup Retro Biosciences, a biotech company with the ambition of “adding 10 years to the human lifespan.” This investment marks
Simply Being Overweight May Not Be Harmful in Aging
April 26, 2023
According to a new large-scale populational study, being overweight is not associated with either significant risks or benefits between the ages of 45 and 85. Obesity, however, is a clear risk factor [1]. BMI plus fat mass index While obesity is widely recognized as a life-long
Reprogramming Fibroblasts in Vivo for Heart Repair
April 25, 2023
Scientists from Duke University have found a way to make adult fibroblasts differentiate into cardiomyocytes, which might help develop better heart attack treatments [1]. The imperfect repair Myocardial infarction, or heart attack, is a leading cause of death and disability. It happens when the blood flow