Category: Research
Major Health-Related Data Project Secures Funding in the UK
March 16, 2021
In the UK, the All-Party Parliamentary Group (APPG) for Longevity has secured funding for its Open Life Data project, which aims to create a framework for effective and ethical collection
David Sinclair and Peter Attia Co-chair $200m Biotech SPAC
March 12, 2021
Another special purpose acquisition company (SPAC) focused on longevity and rejuvenation biotechnology has appeared recently, and with the addition of research rockstars David Sinclair and Peter Attia, it could mean
Managing Stress Responses to Slow Down Aging
March 11, 2021
Longevity research should better incorporate the effects of stress on aging, argues professor Elissa Epel of the University of California, San Francisco [1]. She proposes using the concept of stress
A Summary of NAD+ and Human Aging – Part 2
March 10, 2021
Welcome to part two of a two-part series exploring NAD+ biology; you can find part one here. There are already a myriad of excellent reviews on NAD+ biology in general
Binary Clock Predicts Biological Age
March 9, 2021
Scientists have devised a transcriptome-based aging clock that allows for precise measurement of biological age in C. elegans worms and shows promising results in humans as well [1]. The purpose
Video Gaming as a Geroprotective Strategy
March 8, 2021
Contrary to certain sensationalist articles declaring that video games are harmful, there is, in fact, growing evidence that playing video games may have a positive effect on cognitive health, particularly
Maximon Launches Longevity Biotech Builder
March 8, 2021
We kick off the week with some news from Switzerland and introduce the new longevity biotech company builder Maximon. The enthusiasm for technologies to promote longevity and even increase healthy
The Social Hallmarks of Aging
March 4, 2021
A professor at the University of Southern California has proposed that longevity researchers expand their toolkit to include social hallmarks of aging [1]. This paper is one of a trio
Bioage Clinical Trial for Unexplained Anemia of Aging
March 3, 2021
BioAge, in a recent press release, has announced the start of its phase 2a clinical trial in elderly patients with unexplained anemia of aging. BioAge is a California-based company founded
A Summary of NAD+ and Human Aging – Part 1
March 2, 2021
This is part one of a two-part article where we take a look at NAD+ biology, its history, how it relates to the biology of aging, and the potential for
Digital Health Company Bold Lands $7 Million
February 26, 2021
Thanks to an injection of seed round cash, a new company, Bold, joins the growing pool of organizations that are focused on wellness and disease prevention. The rising interest in
Measuring Age With a Bloodborne Neural Protein
February 25, 2021
A new study shows that functional deterioration of the nervous system contributes to late-life mortality and identifies a related bloodborne biomarker for all-cause mortality [1]. Neurofilament light chain (NfL) is
ChromaDex $25 Million Sale of Common Stock
February 24, 2021
ChromaDex has recently announced that it has agreed a securities purchase agreement for the sale of $25 million of its common stock in a private placement. The private placement was
Longevity Pharmacology has Come of Age
February 24, 2021
A bold feature article published in Drug Discovery Today illustrates the coming of age of longevity pharmacology. Dr. João Pedro de Magalhães, one of the biggest names in longevity research,
SIRT3 Replenishment Reverses Lung Fibrosis in Mice
February 23, 2021
Scientists have successfully reversed persistent lung fibrosis in mice by overexpressing the SIRT3 protein in lung macrophages [1]. Fibrosis: not knowing when to stop Fibrosis may be the true apex
Major Health-Related Data Project Secures Funding in the UK
March 16, 2021
In the UK, the All-Party Parliamentary Group (APPG) for Longevity has secured funding for its Open Life Data project, which aims to create a framework for effective and ethical collection of health-related data on a national level. The UK appears to be one of the first
David Sinclair and Peter Attia Co-chair $200m Biotech SPAC
March 12, 2021
Another special purpose acquisition company (SPAC) focused on longevity and rejuvenation biotechnology has appeared recently, and with the addition of research rockstars David Sinclair and Peter Attia, it could mean a bright future for healthy longevity. We recently talked about how SPACs could transform the longevity
Managing Stress Responses to Slow Down Aging
March 11, 2021
Longevity research should better incorporate the effects of stress on aging, argues professor Elissa Epel of the University of California, San Francisco [1]. She proposes using the concept of stress resilience to capture the differences between beneficial and harmful stress and the multi-level response that mediates
A Summary of NAD+ and Human Aging – Part 2
March 10, 2021
Welcome to part two of a two-part series exploring NAD+ biology; you can find part one here. There are already a myriad of excellent reviews on NAD+ biology in general [1-3], so, in this article, we will be mainly focusing on the NAD+ precursor nicotinamide mononucleotide
Binary Clock Predicts Biological Age
March 9, 2021
Scientists have devised a transcriptome-based aging clock that allows for precise measurement of biological age in C. elegans worms and shows promising results in humans as well [1]. The purpose of aging clocks One of the central questions of longevity research is how to measure biological
Video Gaming as a Geroprotective Strategy
March 8, 2021
Contrary to certain sensationalist articles declaring that video games are harmful, there is, in fact, growing evidence that playing video games may have a positive effect on cognitive health, particularly in older people [1]. Today, we will be taking a look at the scientific evidence to
Maximon Launches Longevity Biotech Builder
March 8, 2021
We kick off the week with some news from Switzerland and introduce the new longevity biotech company builder Maximon. The enthusiasm for technologies to promote longevity and even increase healthy human lifespan seems to be rising in Switzerland. There are frequently articles in the popular press
The Social Hallmarks of Aging
March 4, 2021
A professor at the University of Southern California has proposed that longevity researchers expand their toolkit to include social hallmarks of aging [1]. This paper is one of a trio that offer a fresh perspective on geroscience by trying to integrate findings from a biological approach
Bioage Clinical Trial for Unexplained Anemia of Aging
March 3, 2021
BioAge, in a recent press release, has announced the start of its phase 2a clinical trial in elderly patients with unexplained anemia of aging. BioAge is a California-based company founded in 2015 with a very direct focus on aging. It utilizes a systems biology approach and
A Summary of NAD+ and Human Aging – Part 1
March 2, 2021
This is part one of a two-part article where we take a look at NAD+ biology, its history, how it relates to the biology of aging, and the potential for therapeutic interventions via the so-called NAD+ precursors. What is NAD+? Nicotinamide adenine dinucleotide (NAD) is a
Digital Health Company Bold Lands $7 Million
February 26, 2021
Thanks to an injection of seed round cash, a new company, Bold, joins the growing pool of organizations that are focused on wellness and disease prevention. The rising interest in wellness and healthy aging It’s no secret that the interest in digital health and wellness has
Measuring Age With a Bloodborne Neural Protein
February 25, 2021
A new study shows that functional deterioration of the nervous system contributes to late-life mortality and identifies a related bloodborne biomarker for all-cause mortality [1]. Neurofilament light chain (NfL) is a structural protein found in nerve cells. The nervous system has been implicated in aging and
ChromaDex $25 Million Sale of Common Stock
February 24, 2021
ChromaDex has recently announced that it has agreed a securities purchase agreement for the sale of $25 million of its common stock in a private placement. The private placement was led by an international investor, with ChromaDex agreeing to sell 3,846,153 shares of its common stock
Longevity Pharmacology has Come of Age
February 24, 2021
A bold feature article published in Drug Discovery Today illustrates the coming of age of longevity pharmacology. Dr. João Pedro de Magalhães, one of the biggest names in longevity research, outlined some of the great strides taken in the last two decades, as various discoveries have
SIRT3 Replenishment Reverses Lung Fibrosis in Mice
February 23, 2021
Scientists have successfully reversed persistent lung fibrosis in mice by overexpressing the SIRT3 protein in lung macrophages [1]. Fibrosis: not knowing when to stop Fibrosis may be the true apex predator of humanity. According to one study, fibrotic diseases that cause organ failure are responsible for