Category: Research

Blood vessels

Humacyte in Deal to Develop Prosthetic Vasculature

Tissue engineering company Humacyte is about to make a special purpose acquisition company (SPAC) deal in order to go public. The company is developing bioengineered Human Acellular Vessels (HAVs), which

Injection

The NIA Is Funding Clinical Trials Against Aging

The National Institutes of Aging in the United States, a component of the National Institutes of Health, is funding clinical trials for interventions that directly affect the root causes of

Synthetic organs

Replacing Aging With Jean Hébert

Replacing Aging by Jean Hébert is the latest longevity book published for public consumption. While books such as these seem to be coming out more regularly, readers who have already

the retina

Senescent Cells in the Aging Retina

A review published in the Journal of Neuroinflammation explores the potential application of senotherapies, particularly in the context of treating age-related macular degeneration [1]. Introducing cellular senescence One of the

Helminths under a microscope

Parasitic Worm Infestation for Longevity

A review conducted by researchers at the Institute for Healthy Ageing at University College London in the UK has determined that infestation of the gut microbiome by helminths, a category

An MRI of the human brain

Major Depressive Disorder Linked to Brain Aging

Recent data published in Neuropsychopharmacology has looked at changes in brain connectivity across lifespan and in patients with major depressive disorder. Biological and chronological age Your chronological age is simply

Blood vessels

Humacyte in Deal to Develop Prosthetic Vasculature

Tissue engineering company Humacyte is about to make a special purpose acquisition company (SPAC) deal in order to go public. The company is developing bioengineered Human Acellular Vessels (HAVs), which provide prosthetic vasculature to support the repair, reconstruction, and replacement of blood vessels damaged by injury

Circadian Rhythm Sleep

Atrophy of the Neuronal Circadian Clock Is a Disease of Aging

Today, researcher Victor Bjoerk talks us through his latest published paper, in which he describes a neurodegenerative disease that affects the circadian clock. A circadian clock disease With aging, the brain runs into multiple issues; however, some are more serious than others and cause disease symptoms

Injection

The NIA Is Funding Clinical Trials Against Aging

The National Institutes of Aging in the United States, a component of the National Institutes of Health, is funding clinical trials for interventions that directly affect the root causes of age-related diseases. Direct funding for trials against aging Probably the most important and interesting part of

Synthetic organs

Replacing Aging With Jean Hébert

Replacing Aging by Jean Hébert is the latest longevity book published for public consumption. While books such as these seem to be coming out more regularly, readers who have already tackled David Sinclair’s Lifespan, Nir Barzilai’s Age Later, or Aubrey De Grey’s Ending Aging shouldn’t simply

Longevity Therapeutics banner

Lessons from Longevity Therapeutics 2021 – Part 4

This is the final installment in our coverage of Longevity Therapeutics 2021, a conference that brought together some of the biggest names in longevity research. Read the previous parts here, here, and here. Dr. Andrei Gudkov – Chief Scientific Officer, Genome Protection Andrei Gudkov gave a

Ethics and core values

Developing Our Ethics Code of Longevity Journalism

When lifespan.io was started in 2014 as a crowdfunding platform, we didn’t really know that we would become a news outlet covering longevity research. We didn’t plan to be one. However, after running our first crowdfunding campaign, we realized that public awareness of aging research is

Intestinal bacteria

Proposing Gerobiotics as a New Gut Microbiome Research Field

The aging of the microbiome, the collective bacteria, fungi, protozoa and viruses that live on and inside our bodies, has become a popular research topic in recent years. The microbiome appears to influence aging There has been increasing interest in the influence of this microbial community,

Complicated machinery

The Intertwined Nature of NAD+, CD38, and Senescence

Aging is a multifactorial and complex process; indeed, it is probably the most complex disorder known. It is made up of a combination of dozens of malfunctions locked together in an accelerating spiral of decline. Despite this undeniable complexity, which is captured to some extent by

Male and female intestines

Male and Female Gut Microbiomes Converge With Age

While the gut microbiomes of young men and women are distinct, that difference disappears in older people, according to a new study. These findings add to the growing pool of data that links the gut microbiome and aging, although the nature of the links and the

the retina

Senescent Cells in the Aging Retina

A review published in the Journal of Neuroinflammation explores the potential application of senotherapies, particularly in the context of treating age-related macular degeneration [1]. Introducing cellular senescence One of the most advanced approaches to treating aging and age-related diseases is that of addressing the presence of

A depiction of NAD on a black background

Increasing NAD+ Reduces Amyloids and Benefits Mitochondria

Aging is accompanied by the loss of proteostasis, the accumulation of misfolded proteins and their amyloid aggregates, and mitochondrial dysfunction, which is partially characterized by the loss of mitochondrial homeostasis, the delicate balance that mitochondria need in order to produce energy without polluting the body with

Handshake

lifespan.io Announces Promotions and Expansion

2020 was a year of tremendous growth for lifespan.io. As many of you have likely noticed, our news outlet team has hired two more excellent science journalists, Arkadi Mazin and Greg Gillipsie. Nicola Bagala, who produces LifeXtenShow, was assigned in the summer of 2020 to supervise

Helminths under a microscope

Parasitic Worm Infestation for Longevity

A review conducted by researchers at the Institute for Healthy Ageing at University College London in the UK has determined that infestation of the gut microbiome by helminths, a category of parasitic worms, may be a potential method of curbing the age-related inflammation known as inflammaging,

cute white rat

Neurons from Stem Cells Alleviate Parkinson’s Disease in Rats

In a new study, a group of researchers report on their success in priming stem cells to differentiate into dopaminergic neurons in rat brains. Loss of these neurons is a major cause of Parkinson’s disease [1]. Less neurons, more Parkinson’s Neuronal degeneration is the culprit behind

An MRI of the human brain

Major Depressive Disorder Linked to Brain Aging

Recent data published in Neuropsychopharmacology has looked at changes in brain connectivity across lifespan and in patients with major depressive disorder. Biological and chronological age Your chronological age is simply the amount of time that has passed since you were born, but your biological age represents