Category: Research
Brain, Liver and Muscle Rejuvenated by Calibrating Old Blood
September 3, 2019
Age-related changes to the signals sent and received by our cells travelling via the bloodstream (altered intercellular communication) are thought to be one of the reasons we age. A team
A New Era Beckons as First Drug Is Created by AI
September 2, 2019
Insilico Medicine has achieved a world first by successfully designing, synthesizing, and validating a new drug from the ground up and taking just 46 days to do so. It achieved
Heart Inflammation Causes a Shift in Cell Fate Distribution
August 7, 2019
A study on animals with autoimmune myocarditis was recently released in the journal Cell Reports [1], showing the impact of heart inflammation on the types of immune cell that are
Cellular Reprogramming Reverses Age-Related Vision Loss
August 6, 2019
Today, we want to draw attention to a new study that shows how partial cellular reprogramming was able to reverse cellular aging and address age- and injury-induced blindness in mice.
Clinical Trial of Nicotinamide Riboside Completed
July 22, 2019
Today, we want to highlight a recent human trial of the popular supplement nicotinamide riboside, a compound that has been shown in mice to restore NAD+ levels. The compound has
Machine Learning Identifies Anti-Cancer Molecules in Food
July 17, 2019
The internet is rife with myths and articles making dubious claims about certain foods and their anti-cancer properties. We have all seen the articles of questionable scientific merit gracing social
T Cells Infiltrate the Aging Brain
July 5, 2019
As published in a recent study, researchers have discovered that neural stem cells are impeded by the invasion of T cells, immune cells that are not normally present in the
A Step Closer to Regenerating the Aging Thymus
July 3, 2019
Researchers from the Monash Biomedicine Discovery Institute have made progress in the quest to rejuvenate the aging immune system by identifying the factors responsible for the age-related decline of the
Cytomegalovirus Infection Linked to Metabolic Syndrome
June 26, 2019
Today, we want to highlight a new publication that looks at cytomegalovirus (CMV) and its potential role in the development of metabolic syndrome. What is cytomegalovirus? CMV is part of
NAD+ and Cellular Senescence Pathways Interact
June 11, 2019
A new publication highlights how the complex interaction of NAD+ and cellular senescence pathways may complicate proposed anti-aging therapies that boost NAD+ using precursors. What are epigenetic alterations? One of
Creating Thymus Organoids Using Tissue Engineering
June 5, 2019
Today, we wish to highlight a new open access publication in which the researchers take a novel approach to the regeneration of the thymus, a small but vitally important organ
Telomerase Gene Therapy Ameliorates Neurodegeneration in Mice
June 4, 2019
A group of Spanish researchers, including Dr. Maria Blasco and others at the CNIO, has published a new study that examines the consequences of short telomeres and telomerase deficiency on
The Future of Pensions and Life Extension
May 15, 2019
If you work in social security, it’s possible that your nightmares are full of undying elderly people who keep knocking on your door for pensions that you have no way
Antibiotics and Vitamin C Halt Cancer Growth
May 9, 2019
A new open-access study from researchers at the Biomedical Research Centre in the United Kingdom shows how two antibiotics and Vitamin C can be combined to suppress cancer stem cells
Anti-Aging Gene Therapy for Dogs Coming This Fall
May 8, 2019
In an article last May, we covered how Rejuvenate Bio, a startup biotech company led by Professor George Church, was planning to reverse aging in dogs as a step towards
Brain, Liver and Muscle Rejuvenated by Calibrating Old Blood
September 3, 2019
Age-related changes to the signals sent and received by our cells travelling via the bloodstream (altered intercellular communication) are thought to be one of the reasons we age. A team of researchers, including Drs. Irina and Michael Conboy, has published the results of a new study
A New Era Beckons as First Drug Is Created by AI
September 2, 2019
Insilico Medicine has achieved a world first by successfully designing, synthesizing, and validating a new drug from the ground up and taking just 46 days to do so. It achieved this impressive feat using AI. This is the first time that AI has been used to
Heart Inflammation Causes a Shift in Cell Fate Distribution
August 7, 2019
A study on animals with autoimmune myocarditis was recently released in the journal Cell Reports [1], showing the impact of heart inflammation on the types of immune cell that are formed in the heart. This could have a significant impact on our understanding of cardiac aging.
Cellular Reprogramming Reverses Age-Related Vision Loss
August 6, 2019
Today, we want to draw attention to a new study that shows how partial cellular reprogramming was able to reverse cellular aging and address age- and injury-induced blindness in mice. Epigenetic alterations One of the proposed reasons we age is the changes to gene expression that
Clinical Trial of Nicotinamide Riboside Completed
July 22, 2019
Today, we want to highlight a recent human trial of the popular supplement nicotinamide riboside, a compound that has been shown in mice to restore NAD+ levels. The compound has had impressive results against some aspects of aging in mouse studies, and there is now some
Machine Learning Identifies Anti-Cancer Molecules in Food
July 17, 2019
The internet is rife with myths and articles making dubious claims about certain foods and their anti-cancer properties. We have all seen the articles of questionable scientific merit gracing social media suggesting that such-and-such foods can cure cancer, the majority of which are highly questionable. A
T Cells Infiltrate the Aging Brain
July 5, 2019
As published in a recent study, researchers have discovered that neural stem cells are impeded by the invasion of T cells, immune cells that are not normally present in the neural stem cell niche [1]. The neural stem cell niches Our brains contain neural stem cells
A Step Closer to Regenerating the Aging Thymus
July 3, 2019
Researchers from the Monash Biomedicine Discovery Institute have made progress in the quest to rejuvenate the aging immune system by identifying the factors responsible for the age-related decline of the thymus. The thymus shrinks as we age The thymus is one of the most important organs
Cytomegalovirus Infection Linked to Metabolic Syndrome
June 26, 2019
Today, we want to highlight a new publication that looks at cytomegalovirus (CMV) and its potential role in the development of metabolic syndrome. What is cytomegalovirus? CMV is part of the β-subfamily of herpes viruses, a family of viruses that are believed to have been co-evolving
NAD+ and Cellular Senescence Pathways Interact
June 11, 2019
A new publication highlights how the complex interaction of NAD+ and cellular senescence pathways may complicate proposed anti-aging therapies that boost NAD+ using precursors. What are epigenetic alterations? One of the proposed reasons we age is the changes to gene expression that our cells experience as
Creating Thymus Organoids Using Tissue Engineering
June 5, 2019
Today, we wish to highlight a new open access publication in which the researchers take a novel approach to the regeneration of the thymus, a small but vitally important organ that is key to our immune system. The thymus shrinks as we age The thymus is
Telomerase Gene Therapy Ameliorates Neurodegeneration in Mice
June 4, 2019
A group of Spanish researchers, including Dr. Maria Blasco and others at the CNIO, has published a new study that examines the consequences of short telomeres and telomerase deficiency on the brain [1]. This study addresses an aspect of telomere attrition, one of the primary hallmarks
The Future of Pensions and Life Extension
May 15, 2019
If you work in social security, it’s possible that your nightmares are full of undying elderly people who keep knocking on your door for pensions that you have no way of paying out. Tossing and turning in your bed, you beg for mercy, explaining that there’s
Antibiotics and Vitamin C Halt Cancer Growth
May 9, 2019
A new open-access study from researchers at the Biomedical Research Centre in the United Kingdom shows how two antibiotics and Vitamin C can be combined to suppress cancer stem cells (CSCs) of the breast [1]. While antibiotics are not normally effective against cancer, and Vitamin C
Anti-Aging Gene Therapy for Dogs Coming This Fall
May 8, 2019
In an article last May, we covered how Rejuvenate Bio, a startup biotech company led by Professor George Church, was planning to reverse aging in dogs as a step towards bringing these therapies to us. Those plans are now starting to move forward with news of