May 18, 2026
We have spoken with Reason from Repair Biotechnologies about his company's lead candidate, REP-0004, a drug targeting the liver to reduce excess intracellular free cholesterol. The FDA has granted Repair Bio an orphan drug indication, and the company is aiming for clinical trials by mid-2027. Our conversation also touches on the regulatory challenges and the...
April 10, 2024
Repair Biotechnologies, a company based in Syracuse, New York, has announced findings from early research suggesting that its technology can quickly stop the advancement of atherosclerosis. While these preclinical results are in mice, this approach has the potential for treating atherosclerosis in humans. In March, the company announced that it had received positive feedback from...
July 22, 2020
Reason, author of the anti-aging blog Fight Aging and CEO of Repair Biotechnologies, still isn't convinced that methylation is very useful in assessing biological age or the efficacy of various therapeutics, despite the wide use of methylation-based clocks. He surprised me at this year's Longevity Therapeutics conference in San Francisco by speaking out about the...