Category: News
Creatine Protects Lean Mass Even Without Exercise
September 25, 2026
According to a new study, creatine supplementation might help maintain and increase lean mass even without diet or exercise. It also enhanced the effects of a combined diet and exercise
Giving Cells Fresh Mitochondria Helps Clear Damaged Ones
September 24, 2026
Researchers have discovered that BNIP3, which regulates mitochondrial maintenance, is increased with aging, harming the heart’s ability to process energy. Mitochondrial transplantation was found to be effective against this increase
Physical Activity Delays Ovarian Aging in Mice
September 23, 2026
Results from a recent study suggest a delay in ovarian aging in mice following treadmill training; this effect was mediated by adiponectin. Pharmacologically activating adiponectin receptors extended reproductive span in
Transplanted Immune Cells Donate Mitochondria to Neighbors
September 22, 2026
According to a new study using a mouse model of a rare disease, transplanted immune cells donate their mitochondria to neighboring donor cells, improving energy production and rescuing function [1].
Intermittent Fasting Shows Promise in a Huntington’s Trial
September 21, 2026
In a pilot study, patients engaging in intermittent fasting demonstrated improvements in Huntington’s disease, a neurodegenerative condition currently considered untreatable. However, the study’s size and limitations call for more research
Thymus Grafts Grow in Mouse Spleens, Restoring Immunity
September 18, 2026
In a new study, thymic tissue implanted in the spleen improved immune responses against viruses and tumors and reversed age-related thymic involution in mice [1]. Growing one organ inside another
Clearing Damaged Mitochondria to Fight Skin Photoaging
September 17, 2026
Researchers publishing in Aging Cell have found that a cocktail of molecules released by human umbilical cord mesenchymal stem cells (hUC-MSCs) can mitigate sun-induced skin aging (photoaging) in mice by
An Entirely New Target for Fighting Senescence
September 15, 2026
Researchers have established how a protein that is nearly absent in the literature, PTCHD4, is linked to cellular senescence. Very little previous work In most papers, after a customary discussion
Mitochondrial Performance May Strongly Influence Learning
September 14, 2026
A team of researchers has discovered that mitochondrial health and location may be critical to why cognitive plasticity decreases with age. Old mammals and new tricks The adage ‘you can’t
Lung Fibrosis Drug Lowers Biological Age Estimates
September 11, 2026
Six different aging clocks detected younger blood protein profiles in patients taking the experimental lung-fibrosis drug rentosertib. This suggests possible anti-aging effects, but separating those from the narrower benefits of
Calcium Mishandling Contributes to Muscle Loss
September 10, 2026
Researchers have discovered and explained how calcium mishandling in muscle cells leads to long-term muscle weakness in older people. Calcium is not just for bones Skeletal muscle cells use calcium
Comparing the Responsiveness of Epigenetic Aging Biomarkers
September 9, 2026
In a recent study, researchers have evaluated how responsive several DNA methylation (DNAm) biomarkers are to a range of longevity interventions [1]. Waiting too long Testing lifespan-extending interventions in humans
Late-Life GLP-1 Treatment Increases Lifespan in Female Mice
September 8, 2026
In a new study, semaglutide given late in life increased median lifespan in female mice by more than 12% and improved various health markers. Semaglutide’s effect possibly went beyond caloric
Mice With Growth Hormone Halted in Middle Age Live Longer
September 7, 2026
Researchers publishing in Aging Cell have described how stopping growth hormone receptor production in midlife significantly lengthens the lives of mice. Growth but diabetes Growth hormone affects the metabolism of
The Last Generation to Die: Interview With Tim Maupin
September 3, 2026
Filmmaker Tim Maupin has spent a number of years developing The Last Generation to Die, a near-future film about what happens when the first true rejuvenation technologies arrive and who
Creatine Protects Lean Mass Even Without Exercise
September 25, 2026
According to a new study, creatine supplementation might help maintain and increase lean mass even without diet or exercise. It also enhanced the effects of a combined diet and exercise intervention [1]. How to lose weight but not muscle As people age, they often accumulate fat
Giving Cells Fresh Mitochondria Helps Clear Damaged Ones
September 24, 2026
Researchers have discovered that BNIP3, which regulates mitochondrial maintenance, is increased with aging, harming the heart’s ability to process energy. Mitochondrial transplantation was found to be effective against this increase in a mouse model. The heart needs energy Mitophagy, the process of eliminating damaged mitochondria, is
Physical Activity Delays Ovarian Aging in Mice
September 23, 2026
Results from a recent study suggest a delay in ovarian aging in mice following treadmill training; this effect was mediated by adiponectin. Pharmacologically activating adiponectin receptors extended reproductive span in mice. [1] Beyond reproduction The female reproductive system strongly influences the female aging trajectory, and its
Transplanted Immune Cells Donate Mitochondria to Neighbors
September 22, 2026
According to a new study using a mouse model of a rare disease, transplanted immune cells donate their mitochondria to neighboring donor cells, improving energy production and rescuing function [1]. Here, have some mitochondria Friedreich’s ataxia is a rare genetic disease in which deficiency in the
Intermittent Fasting Shows Promise in a Huntington’s Trial
September 21, 2026
In a pilot study, patients engaging in intermittent fasting demonstrated improvements in Huntington’s disease, a neurodegenerative condition currently considered untreatable. However, the study’s size and limitations call for more research [1]. Fast to survive Huntington’s disease is an inherited, progressive neurodegenerative disorder caused by an expansion
Thymus Grafts Grow in Mouse Spleens, Restoring Immunity
September 18, 2026
In a new study, thymic tissue implanted in the spleen improved immune responses against viruses and tumors and reversed age-related thymic involution in mice [1]. Growing one organ inside another The thymus is a small but crucial organ, where T cells mature to become the backbone
Clearing Damaged Mitochondria to Fight Skin Photoaging
September 17, 2026
Researchers publishing in Aging Cell have found that a cocktail of molecules released by human umbilical cord mesenchymal stem cells (hUC-MSCs) can mitigate sun-induced skin aging (photoaging) in mice by restoring their cells’ ability to get rid of their own damaged mitochondria (mitophagy). Wrinkles are only
An Entirely New Target for Fighting Senescence
September 15, 2026
Researchers have established how a protein that is nearly absent in the literature, PTCHD4, is linked to cellular senescence. Very little previous work In most papers, after a customary discussion of the mechanics of cellular senescence and current methods of handling it and its repercussions, the
Mitochondrial Performance May Strongly Influence Learning
September 14, 2026
A team of researchers has discovered that mitochondrial health and location may be critical to why cognitive plasticity decreases with age. Old mammals and new tricks The adage ‘you can’t teach an old dog new tricks’ is true across a wide variety of organisms; neural plasticity
Lung Fibrosis Drug Lowers Biological Age Estimates
September 11, 2026
Six different aging clocks detected younger blood protein profiles in patients taking the experimental lung-fibrosis drug rentosertib. This suggests possible anti-aging effects, but separating those from the narrower benefits of treating fibrosis remains a challenge [1]. The AI-developed drug Many drugs developed for particular diseases act
Calcium Mishandling Contributes to Muscle Loss
September 10, 2026
Researchers have discovered and explained how calcium mishandling in muscle cells leads to long-term muscle weakness in older people. Calcium is not just for bones Skeletal muscle cells use calcium ions to control how and when they contract. This activity is modulated by CaMKII, a protein
Comparing the Responsiveness of Epigenetic Aging Biomarkers
September 9, 2026
In a recent study, researchers have evaluated how responsive several DNA methylation (DNAm) biomarkers are to a range of longevity interventions [1]. Waiting too long Testing lifespan-extending interventions in humans has a major problem: it can take many years, or even decades, to see results. Nobody
Late-Life GLP-1 Treatment Increases Lifespan in Female Mice
September 8, 2026
In a new study, semaglutide given late in life increased median lifespan in female mice by more than 12% and improved various health markers. Semaglutide’s effect possibly went beyond caloric restriction [1]. Old mice, new drugs GLP-1 receptor agonists, which act on a hormone that regulates
Mice With Growth Hormone Halted in Middle Age Live Longer
September 7, 2026
Researchers publishing in Aging Cell have described how stopping growth hormone receptor production in midlife significantly lengthens the lives of mice. Growth but diabetes Growth hormone affects the metabolism of fats (lipids), increasing the levels of circulating fatty acids while increasing insulin-like growth factor 1 (IGF-1)
The Last Generation to Die: Interview With Tim Maupin
September 3, 2026
Filmmaker Tim Maupin has spent a number of years developing The Last Generation to Die, a near-future film about what happens when the first true rejuvenation technologies arrive and who gets left behind. The project has now reached the top 65 of the Future Vision XPrize,