Category: News
Fisetin May Be Useful in Treating Pulmonary Fibrosis
January 4, 2021
The results of a recent study suggest that fisetin appears to reduce the development of bleomycin-induced pulmonary fibrosis [1]. Fisetin is a plant polyphenol and part of the flavonoid group
Emerging From the Pro-Aging Trance
January 1, 2021
Has the tide turned for rejuvenation biotechnology? It seems that opposition against medicine that seeks to slow, halt, or reverse aging may be slowly starting to crumble. For example, lifespan.io’s
Rejuvenation Roundup December 2020
December 23, 2020
Happy holidays from the Lifespan Extension Advocacy Foundation! While 2020 has been a trying year in many respects, rejuvenation research has continued throughout, and we are pleased to announce that
Stem Cell Growth Factors Treat Alzheimer’s in Aged Mice
December 23, 2020
A new article published in Aging and Disease has taken a look at what two stem cell-activating growth factors can do in aged mice with Alzheimer’s-like pathology. Alzheimer’s disease (AD)
Biohackers Perform First Plasma Dilution Experiment on Humans
December 22, 2020
We interviewed a group of Russian biohackers who performed a plasma dilution experiment on themselves. This experiment, the first of its kind, was based on previous mouse studies by Drs.
Holiday Wishes from lifespan.io
December 21, 2020
As the holidays approach, I want to take this opportunity to sincerely thank you for being part of our community at lifespan.io and helping to bring an end to the
NOVOS Plans to Launch a Nutraceutical for Aging
December 21, 2020
Today, we want to spotlight NOVOS, a nutraceutical company that is focused on developing science-based nutraceuticals to slow down aging and that will offer tests to track people’s aging processes
MYSM1 Prolongs Lifespan by Regulating DNA Repair
December 17, 2020
New research has shown that a DNA repair gene modulates lifespan in mice [1]. This may serve as a therapeutic avenue or at least open the way towards dissecting the
Decellularized, Functional Thymus Regeneration in Mice
December 16, 2020
Recent research published in Nature Communications has regenerated a functional thymus in mice, making several other discoveries along the way [1]. A new sub-type of thymus cell emerges Although it
New Discovery in How Stem Cells Protect Telomeres
December 15, 2020
Scientists have discovered a new telomere-protecting mechanism in embryonic stem cells. This discovery can bring us closer to solving the notorious problem of telomere attrition and to understanding the immortality
New Aging Clock May Be Most Accurate to Date
December 14, 2020
These days, it seems like you cannot go for a walk without tripping over another aging clock, and today is no exception. DeepMAge, a DNA methylation aging clock developed using
Gene Therapy Trial Successfully Improves Vision
December 11, 2020
A team of researchers, including Dr. Patrick Yu-Wai-Man from the University of Cambridge and Dr. José-Alain Sahel from the University of Pittsburgh and Institut de la Vision, Paris, has successfully
Aging Brain Function Partially Restored With Small Molecule
December 10, 2020
Researchers from the University of California, San Francisco have discovered that a small molecule partially restores the cognitive abilities of mice suffering from age-related memory decline [1]. A response to
Kidney Progenitor Cells Derived from Urine
December 9, 2020
Recent data published in Scientific Reports has characterized human urine-derived renal stem cells, a potential non-invasive source for kidney tissue engineering and regenerative medicine. An unlikely source for kidney cells
Reviewing CD38, a Regulator of NAD+
December 8, 2020
We recently explored why NAD+ declines during aging, and today, we want to spotlight a new review that takes a deep dive into CD38, one of the reasons for this
Fisetin May Be Useful in Treating Pulmonary Fibrosis
January 4, 2021
The results of a recent study suggest that fisetin appears to reduce the development of bleomycin-induced pulmonary fibrosis [1]. Fisetin is a plant polyphenol and part of the flavonoid group in the flavonol sub-category. The earliest record of isolated fisetin dates back to 1833 from the
Emerging From the Pro-Aging Trance
January 1, 2021
Has the tide turned for rejuvenation biotechnology? It seems that opposition against medicine that seeks to slow, halt, or reverse aging may be slowly starting to crumble. For example, lifespan.io’s current crowdfunding campaign is going extremely well, and journalists begin to talk about senolytics in more
Rejuvenation Roundup December 2020
December 23, 2020
Happy holidays from the Lifespan Extension Advocacy Foundation! While 2020 has been a trying year in many respects, rejuvenation research has continued throughout, and we are pleased to announce that we have plenty to discuss before we part for the holiday season. LEAF News We would
Stem Cell Growth Factors Treat Alzheimer’s in Aged Mice
December 23, 2020
A new article published in Aging and Disease has taken a look at what two stem cell-activating growth factors can do in aged mice with Alzheimer’s-like pathology. Alzheimer’s disease (AD) is perhaps the most age-related of all age-related diseases. Perhaps not coincidentally, it has also been
Biohackers Perform First Plasma Dilution Experiment on Humans
December 22, 2020
We interviewed a group of Russian biohackers who performed a plasma dilution experiment on themselves. This experiment, the first of its kind, was based on previous mouse studies by Drs. Irina and Michael Conboy. Some molecules, while essential for various body functions, can be harmful when
Holiday Wishes from lifespan.io
December 21, 2020
As the holidays approach, I want to take this opportunity to sincerely thank you for being part of our community at lifespan.io and helping to bring an end to the diseases of aging. 2020 has been a difficult year, but through it all, you have helped
NOVOS Plans to Launch a Nutraceutical for Aging
December 21, 2020
Today, we want to spotlight NOVOS, a nutraceutical company that is focused on developing science-based nutraceuticals to slow down aging and that will offer tests to track people’s aging processes and get a better picture of their health. The company is launching two new supplements: NOVOS
MYSM1 Prolongs Lifespan by Regulating DNA Repair
December 17, 2020
New research has shown that a DNA repair gene modulates lifespan in mice [1]. This may serve as a therapeutic avenue or at least open the way towards dissecting the links between DNA damage and senescence. MYSM1 is a gene that removes a molecular mark known
Decellularized, Functional Thymus Regeneration in Mice
December 16, 2020
Recent research published in Nature Communications has regenerated a functional thymus in mice, making several other discoveries along the way [1]. A new sub-type of thymus cell emerges Although it is imperative to our immune health, the thymus is an under-studied organ that slowly disappears as
New Discovery in How Stem Cells Protect Telomeres
December 15, 2020
Scientists have discovered a new telomere-protecting mechanism in embryonic stem cells. This discovery can bring us closer to solving the notorious problem of telomere attrition and to understanding the immortality of cancer cells [1]. Keeping telomeres in the loop One function of telomeres is to prevent
New Aging Clock May Be Most Accurate to Date
December 14, 2020
These days, it seems like you cannot go for a walk without tripping over another aging clock, and today is no exception. DeepMAge, a DNA methylation aging clock developed using deep learning, has recently been created by the Hong Kong-based company Deep Longevity. There are two
Gene Therapy Trial Successfully Improves Vision
December 11, 2020
A team of researchers, including Dr. Patrick Yu-Wai-Man from the University of Cambridge and Dr. José-Alain Sahel from the University of Pittsburgh and Institut de la Vision, Paris, has successfully treated 37 participants suffering from Leber hereditary optic neuropathy (LHON). A landmark trial for mitochondrial gene
Aging Brain Function Partially Restored With Small Molecule
December 10, 2020
Researchers from the University of California, San Francisco have discovered that a small molecule partially restores the cognitive abilities of mice suffering from age-related memory decline [1]. A response to damage As the researchers explain, when neurons detect that something has gone wrong, either through the
Kidney Progenitor Cells Derived from Urine
December 9, 2020
Recent data published in Scientific Reports has characterized human urine-derived renal stem cells, a potential non-invasive source for kidney tissue engineering and regenerative medicine. An unlikely source for kidney cells The kidney is, by far, the most frequently transplanted organ. This is because donors are much
Reviewing CD38, a Regulator of NAD+
December 8, 2020
We recently explored why NAD+ declines during aging, and today, we want to spotlight a new review that takes a deep dive into CD38, one of the reasons for this decline [1]. The review focuses on one of the primary culprits of NAD+ decline, the enzyme