Category: News
A Non-Invasive Biomarker to Track Cellular Senescence
April 8, 2021
A lipid metabolite could serve as a novel biomarker to test the performance of senolytics, according to a new study [1]. Such a biomarker can be detected from blood or
Jim Mellon’s Funding of Longevity Projects
April 7, 2021
How does an idea that is too unconventional for mainstream channels get funded? Often, even venture capitalist firms are too risk-averse, and government funding agencies are too entrenched in the
The “Not in my Lifetime” argument
April 7, 2021
For much of human history, living up to a ripe old age was seen as a gift from the gods, an aberration, or just the product of sheer luck. Given
SenNet: The NIH Large-Scale Cellular Senescence Initiative
April 6, 2021
The National Institute of Health is going all-in on cellular senescence with its recently announced SenNet program. We asked two of the leading experts in aging research to weigh in
Selenium Supplements Protect Against Obesity in Mice
April 5, 2021
A recent study has shown that mice given selenium supplements were protected against the effects of a high-fat diet, similar to mice with a restricted methonine intake. Methonine restriction and
Increased Longevity and Cultural Stagnation
April 5, 2021
One concern that people have about increasing healthy human longevity is that society would become stagnant and innovation would cease as a result of people living too long. However, stagnation
Increased Longevity and Lost Motivation
April 3, 2021
Of all the concerns and objections that I’ve bumped into as a rejuvenation advocate, saying that healthy longevity would deprive us of motivation in life is by far the most
The Senate Special Committee on Aging Needs Better Focus
April 2, 2021
The good news is that the United States Senate has a Special Committee on Aging. The bad news is that it has little to do with the actual processes of
VitaDAO to Launch Longevity Biotech by Democracy
April 1, 2021
VitaDAO wants to democratize biotech VitaDAO will aim to fund longevity research, give its members ownership of the resulting IP, and allow members to vote on the direction of the
Rejuvenation Roundup March 2021
April 1, 2021
It might be April Fool’s Day, but with the ongoing pandemic, age-related diseases are even less funny this year than they were last year. Let’s take a look at what
NAD+ Eases Symptoms of a Premature Aging Disease in Mice
March 31, 2021
Scientists have alleviated symptoms of the rare premature aging disease ataxia-telangiectasia using NAD+ supplementation in a mouse model [1]. This success deepens our understanding of the role NAD+ plays in
Stopping Colorectal Cancer From Proliferating
March 29, 2021
In a cell culture study, researchers have discovered that forcing cancer cells to differentiate into somatic cells can cause them to stop proliferating. Cancer, stem cells, and proliferation The danger
Increased Longevity and Immortal Dictators
March 26, 2021
Suppose there was a country ruled by an evil dictator. Further, suppose the entire world was plagued by a terrible disease affecting 100% of the population. The disease isn’t infectious,
What is NMN? A Summary of Nicotinamide Mononucleotide
March 26, 2021
What is NMN? NMN is short for nicotinamide mononucleotide, a naturally occurring molecule present in all species. On the molecular level, it is a ribonucleotide, a basic structural unit of
Shortened Telomeres Increase Kidney Fibrosis Rates in Mice
March 25, 2021
A team of researchers led by Dr. Maria Blasco of the Spanish National Cancer Research Center has shown that shorter telomeres make mice more susceptible to kidney fibrosis [1]. The
A Non-Invasive Biomarker to Track Cellular Senescence
April 8, 2021
A lipid metabolite could serve as a novel biomarker to test the performance of senolytics, according to a new study [1]. Such a biomarker can be detected from blood or urine, allowing for non-invasive testing, and experiments have shown that it plays a functional role in
Jim Mellon’s Funding of Longevity Projects
April 7, 2021
How does an idea that is too unconventional for mainstream channels get funded? Often, even venture capitalist firms are too risk-averse, and government funding agencies are too entrenched in the status quo, to consider the most revolutionary ideas. Commonly given advice in the start-up world tells
The “Not in my Lifetime” argument
April 7, 2021
For much of human history, living up to a ripe old age was seen as a gift from the gods, an aberration, or just the product of sheer luck. Given that up to the beginning of the twentieth century, many of us succumbed to disease at
SenNet: The NIH Large-Scale Cellular Senescence Initiative
April 6, 2021
The National Institute of Health is going all-in on cellular senescence with its recently announced SenNet program. We asked two of the leading experts in aging research to weigh in on this initiative. The NIH takes notice Cellular senescence has been at the forefront of longevity
Selenium Supplements Protect Against Obesity in Mice
April 5, 2021
A recent study has shown that mice given selenium supplements were protected against the effects of a high-fat diet, similar to mice with a restricted methonine intake. Methonine restriction and caloric restriction It is well known among the longevity community that restricting calories leads to health
Increased Longevity and Cultural Stagnation
April 5, 2021
One concern that people have about increasing healthy human longevity is that society would become stagnant and innovation would cease as a result of people living too long. However, stagnation probably won’t happen as a result of increased longevity. Increasing human longevity vs the status quo
Increased Longevity and Lost Motivation
April 3, 2021
Of all the concerns and objections that I’ve bumped into as a rejuvenation advocate, saying that healthy longevity would deprive us of motivation in life is by far the most bizarre. I have a hard time believing this concern is so widespread that it needs discussing,
The Senate Special Committee on Aging Needs Better Focus
April 2, 2021
The good news is that the United States Senate has a Special Committee on Aging. The bad news is that it has little to do with the actual processes of aging and has not meaningfully furthered the research necessary to develop medical treatments for aging itself.
VitaDAO to Launch Longevity Biotech by Democracy
April 1, 2021
VitaDAO wants to democratize biotech VitaDAO will aim to fund longevity research, give its members ownership of the resulting IP, and allow members to vote on the direction of the organization. Few would argue that the drug development process is efficient. Even as the technology surrounding
Rejuvenation Roundup March 2021
April 1, 2021
It might be April Fool’s Day, but with the ongoing pandemic, age-related diseases are even less funny this year than they were last year. Let’s take a look at what people have been doing about them in March. LEAF News Promising to connect biotech innovators and
NAD+ Eases Symptoms of a Premature Aging Disease in Mice
March 31, 2021
Scientists have alleviated symptoms of the rare premature aging disease ataxia-telangiectasia using NAD+ supplementation in a mouse model [1]. This success deepens our understanding of the role NAD+ plays in aging. The ubiquitous facilitator The coenzyme nicotinamide adenine dinucleotide (NAD+) is one of the foundations of
Stopping Colorectal Cancer From Proliferating
March 29, 2021
In a cell culture study, researchers have discovered that forcing cancer cells to differentiate into somatic cells can cause them to stop proliferating. Cancer, stem cells, and proliferation The danger of cancer is from its proliferation: its uncontrolled division within the body. This proliferation is explained
Increased Longevity and Immortal Dictators
March 26, 2021
Suppose there was a country ruled by an evil dictator. Further, suppose the entire world was plagued by a terrible disease affecting 100% of the population. The disease isn’t infectious, but it is congenital. It progresses extremely slowly over the course of several decades, but it
What is NMN? A Summary of Nicotinamide Mononucleotide
March 26, 2021
What is NMN? NMN is short for nicotinamide mononucleotide, a naturally occurring molecule present in all species. On the molecular level, it is a ribonucleotide, a basic structural unit of nucleic acid RNA. In form it consists of a nicotinamide group, a ribose and a phosphate
Shortened Telomeres Increase Kidney Fibrosis Rates in Mice
March 25, 2021
A team of researchers led by Dr. Maria Blasco of the Spanish National Cancer Research Center has shown that shorter telomeres make mice more susceptible to kidney fibrosis [1]. The new study not only clearly demonstrates this link but also provides mouse models which can be